Clinical Efficacy of Noninvasive Cryolipolysis and Its Effects on Peripheral Nerves

Sydney R. Coleman1, Kulveen Sachdeva2, Barbara M. Egbert3, Jessica Preciado4, John G. Allison4
1Department of Surgery, NYU School of Medicine, New York, USA
2San Ramon Regional Medical Center, San Ramon, USA
3Department of Dermatology and Pathology, Stanford University Medical Center, Palo Alto, USA
4Zeltiq Aesthetics, Pleasanton, USA

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Manstein D, Laubach H, Watanabe K, Anderson RR (2008) A novel cryotherapy method of non-invasive, selective lipolysis. Lasers Surg Med S20(40):104

Preciado J, Allison J (2008) The effect of cold exposure on adipocytes: examining a novel method for the noninvasive removal of fat. Oral presentation at the society for cryobiology annual meeting, 21 July 2008

Rispat G, Slaoui M, Weber D, Salemink P, Berthoux C, Shrivastava R (1993) Haematological and plasma biochemical values for healthy Yucatan micropigs. Lab Anim 27:368–373

Kennedy WR, Wendelschafer-Crabb G, Polydefkis M, McArthur JC (2005) Pathology and quantitation of cutaneous innervation. In: Dyck PJ, Thomas PK (eds) Peripheral neuropathy. Elsevier, Philadelphia, PA, pp 869–895

Kennedy WR, Wendelschafer-Crabb G, Johnson T (1996) Quantitation of epidermal nerves in diabetic neuropathy. Neurology 47:1042–1048

Nolano M, Simone DA, Wendelschafer-Crabb G, Johnson T, Hazen E, Kennedy WR (1999) Topical capsaicin in humans: parallel loss of epidermal nerve fibers and pain sensation. Pain 81:135–145

Wiadrowski TP, Marshman G (2001) Subcutaneous fat necrosis of the newborn following hypothermia and complicated by pain and hypercalcaemia. Australas J Dermatol 42:207–210

Diamantis S, Bastek T, Groben P, Morrell D (2006) Subcutaneous fat necrosis in a newborn following icebag application for treatment of supraventricular tachycardia. J Perinatol 26:518–520

Taylor CA (1949) Survival of rat skin and changes in hair pigmentation following freezing. J Exp Zool 110:77–111

Shurtleff D, Gilliatt RW, Thomas JR, Pezeshkpour GH (1993) An assessment of peripheral nerve damage in the rat following nonfreezing cold exposure: an electrophysiological and histopathologic examination. Technical report, Jan 1991–Jan 1992. Naval Medical Research Institute: Bethesda, MD. http://stinet.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=ADA264293

Irwin MS (1996) Nature and mechanism of peripheral nerve damage in an experimental model of nonfreezing cold injury. Ann R Coll Surg Engl 78:372–379

Irwin MS, Sanders R, Green CJ, Terenghi G (1997) Neuropathy in nonfreezing cold injury (trench foot). J R Soc Med 90:433–438

Jia J, Pollock M, Jia J (1998) Cold injury to nerves is not due to ischaemia alone. Brain 21:989–1001

Iida H, Schmelzer JD, Schmeichel AM, Wang Y, Low PA (2003) Peripheral nerve ischemia: reperfusion injury and fiber regeneration. Exp Neurol 184:997–1002

Saray A, Can B, Akbiyik F, Askar I (1999) Ischaemia-reperfusion injury of the peripheral nerve: an experimental study. Microsurgery 19:374–380

Schmelzer JD, Zochodne DW, Low PA (1989) Ischemic and reperfusion injury of rat peripheral nerve. Proc Natl Acad Sci U S A 86:1639–1642