Clinical Course and Outcome of Human Monkeypox in Nigeria

Clinical Infectious Diseases - Tập 71 Số 8 - Trang e210-e214 - 2020
Dimie Ogoina1, Michael Iroezindu2, Hendris Izibewule James1, Regina Oladokun3, Adesola Yinka-Ogunleye4, Paul Wakama5, Bolaji Otike-Odibi6, Liman Muhammed Usman7, Emmanuel Obazee6, Olusola Aruna8, Chikwe Ihekweazu4
1Infectious Disease Unit, Niger Delta University Teaching Hospital, Okolobiri, Bayelsa, Nigeria
2Infectious Disease Unit, Federal Medical Centre Owerri/University of Nigeria Teaching Hospital, Enugu, Nigeria
3Paediatric Infectious Disease Unit, University College Hospital, Ibadan, Oyo State, Nigeria
4Nigerian Centre for Disease Control, Abuja, Federal Capital Territory, Nigeria
5Nigerian Prison Services, Port Harcourt, Rivers State, Nigeria
6Department of Medicine, University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria
7Ministry of Health, Nasarawa, Nasarawa State, Nigeria
8Global Public Health Department, Public Health England, London, United Kingdom

Tóm tắt

Abstract In a retrospective review of hospital records of 40 human monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin eruptions. Five deaths were reported. Compared to human immunodeficiency virus (HIV)–negative cases, HIV type 1–coinfected cases had more prolonged illness, larger lesions, and higher rates of both secondary bacterial skin infections and genital ulcers.

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