Clinical Analysis of 40 Cases of childhood‐Onset Behçet's Disease

Pediatric Dermatology - Tập 11 Số 2 - Trang 95-101 - 1994
Dong‐Kun Kim1, Sung Nam Chang2, Dongsik Bang2, Eun‐So Lee3, Sungnack Lee3
1Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea
2Department of Dermatology Yonsei University College of Medicine Seoul
3Department of Dermatology, Ajou University School of Medicine, Suwon, Korea

Tóm tắt

Abstract: Behçet's disease is a chronic, relapsing, idiopathic, multisystem condition characterized by mucocutaneous, ocular, gastrointestinal, articular, vascular, urogenital, and neurologic involvement. Usually the onset occurs between 20 and 30 years of age; it is very uncommon in children. We analyzed 40cases of childhood‐onset Behçet's disease. The male: female ratio was 0·67 the most frequent major sign was oral ulceration, appearing inall patients. Other major sings were genital ulcers (33 patients) skin lesions (29), and ocular lesions (11). the average time interval between the initial oral ulceration and the second major manifestation, the third and fourth features rapidly developed within one to two years. The most frequent minor sign was arthritis, occurring in 11of 40 patients. Intestinal, neurologic, and renal involvement was also present. From our results, we concluded that oral ulceration, which is the most common initia manifestation, should not be neglected in children, since it may signal Behçet's disease.

Từ khóa


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Thông tin xuất bản

Pediatric Dermatology

Tập 11 Số 2

95-101

Thông tin tác giả