Clinging to life: cell to matrix adhesion and cell survival
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Schwartz MA, Assoian RK: Integrins and cell proliferation: Regulation of cyclin-dependent kinases via cytoplasmic signaling pathways. J Cell Sci 114: 2553–2560, 2001
Giancotti FG, Tarone G: Positional control of cell fate through joint integrin/receptor protein kinase signaling. Annu Rev Cell Dev Biol 19: 173–206, 2003
Howe AK, Aplin AE, Juliano RL: Anchorage-dependent erk signaling–mechanisms and consequences. Curr Opin Genet Dev 12: 30–35, 2002
Juliano RL: Signal transduction by cell adhesion receptors and the cytoskeleton: Functions of integrins, cadherins, selectins, and immunoglobulin-superfamily members. Annu Rev Pharmacol Toxicol 42: 283–323, 2002
Grossmann J: Molecular mechanisms of “detachment-induced apoptosis–anoikis”. Apoptosis 7: 247–260, 2002
Stupack DG, Cheresh DA: Get a ligand, get a life: Integrins, signaling and cell survival. J Cell Sci 115: 3729–3738, 2002
Alahari SK, Reddig PJ, Juliano RL: Biological aspects of signal transduction by cell adhesion receptors. Int Rev Cytol 220: 145–184, 2002
Martin SS, Vuori K: Regulation of Bcl-2 proteins during anoikis and amorphosis. Biochim Biophys Acta 1692: 145–157, 2004
Cory S, Huang DC, Adams JM: The Bcl-2 family: Roles in cell survival and oncogenesis. Oncogene 22: 8590–8607, 2003
Salvesen GS, Abrams JM: Caspase activation—stepping on the gas or releasing the brakes? Lessons from humans and flies. Oncogene 23: 2774–2784, 2004
Shi Y: Mechanisms of caspase activation and inhibition during apoptosis. Molecular Cell 9: 459–470, 2002
Adams JM, Cory S: Apoptosomes: Engines for caspase activation. Curr Opin Cell Biol 14: 715–720, 2002
Ozoren N, El-Deiry WS: Cell surface death receptor signaling in normal and cancer cells. Semin Cancer Biol 13: 135–147, 2003
Cory S, Adams JM: The BCL2 family: Regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647–656, 2002
Altieri DC: The molecular basis and potential role of survivin in cancer diagnosis and therapy. Trends in Molecular Medicine 7: 542–547, 2001
Frisch SM, Francis H: Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619–626, 1994
Puthalakath H, Huang DCS, O'Reilly LA, King SM, Strasser A: The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Molecular Cell 3: 287–296, 1999
Puthalakath H, Villunger A, O'Reilly LA, Beaumont JG, Coultas L, Cheney RE, Huang DC, Strasser A: Bmf: A proapoptotic BH3-only protein regulated by interaction with the myosin v actin motor complex, activated by anoikis. Science 293: 1829–1832, 2001
Le Gall M, Chambard JC, Breittmayer JP, Grall D, Pouyssegur J, Van Obberghen-Schilling E: The p42/p44 MAP kinase pathway prevents apoptosis induced by anchorage and serum removal. Mol Biol Cell 11: 1103–1112, 2000
Schulze A, Lehmann K, Jefferies HBJ, McMahon M, Downward J: Analysis of the transcriptional program induced by Raf in epithelial cells. Genes Dev 15: 981–994, 2001
Ley R, Ewings KE, Hadfield K, Howes E, Balmanno K, Cook SJ: Extracellular signal-regulated kinases 1/2 are serum-stimulated “BimEL kinases” that bind to the BH3-only protein bimel causing its phosphorylation and turnover. J Biol Chem 279: 8837–8847, 2004
Biswas SC, Greene LA: Nerve growth factor (NGF) down-regulates the Bcl-2 homology 3 (BH3) domain-only protein bim and suppresses its proapoptotic activity by phosphorylation. J Biol Chem 277: 49511–49516, 2002
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS: Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nat Cell Biol 5: 733–740, 2003
Marani M, Hancock D, Lopes R, Tenev T, Downward J, Lemoine NR: Role of Bim in the survival pathway induced by Raf in epithelial cells. Oncogene 23: 2431–2441, 2004
Wang P, Gilmore AP, Streuli CH: Bim is an apoptosis sensor that responds to loss of survival signals delivered by epidermal growth factor but not those provided by integrins. J Biol Chem 279: 41280–41285, 2004
Wang P, Valentijn AJ, Gilmore AP, Streuli CH: Early events in the anoikis program occur in the absence of caspase activation. J Biol Chem 278: 19917–19925, 2003
Gilmore AP, Metcalfe AD, Romer LH, Streuli CH: Integrin-mediated survival signals regulate the apoptotic function of Bax through its conformation and subcellular localization. J Cell Biol 149: 431–446, 2000
Valentijn AJ, Metcalfe AD, Kott J, Streuli CH, Gilmore AP: Spatial and temporal changes in Bax subcellular localization during anoikis. J Cell Biol 162: 599–612, 2003
Rytomaa M, Martins LM, Downward J: Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis. Curr Biol 9: 1043–1046, 1999
Rytomaa M, Lehmann K, Downward J: Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: Inhibition by PKB/Akt but not Raf signalling. Oncogene 19: 4461–4468, 2000
Frisch SM: Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis. Current Biology 9: 1047–1049, 1999
Valentijn AJ, Gilmore AP: Translocation of full-length Bid to mitochondria during anoikis. J Biol Chem 279: 32848–32857, 2004
Matter ML, Ruoslahti E: A signaling pathway from the α5β1 and αvβ3 integrins that elevates Bcl-2 transcription. J Biol Chem 276: 27757–27763, 2001
Zhang Z, Vuori K, Reed JC, Ruoslahti E: The α5β1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression. Proceedings Of The PNAS Of The United States Of America 92: 6161–6165, 1995
Jan Y, Matter M, Pai JT, Chen YL, Pilch J, Komatsu M, Ong E, Fukuda M, Ruoslahti E: A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and groucho/tle corepressors. Cell 116: 751–762, 2004
Nicholson KM, Anderson NG: The protein kinase B/Akt signalling pathway in human malignancy. Cellular Signalling 14: 381–395, 2002
Pankov R, Cukierman E, Clark K, Matsumoto K, Hahn C, Poulin B, Yamada KM: Specific β1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A. J Biol Chem 278: 18671–18681, 2003
Janes SM, Watt FM: Switch from α vβ 5 to α vβ 6 integrin expression protects squamous cell carcinomas from anoikis. J Cell Biol 166: 419–431, 2004
Miyazaki T, Shen M, Fujikura D, Tosa N, Kon S, Uede T, Reed JC: Functional role of death associated protein 3 (DAP3) in anoikis. J Biol Chem 2004
Fornaro M, Plescia J, Chheang S, Tallini G, Zhu YM, King M, Altieri DC, Languino LR: Fibronectin protects prostate cancer cells from tumor necrosis factor-α-induced apoptosis via the Akt/survivin pathway. J Biol Chem 278: 50402–50411, 2003
Douma S, Van Laar T, Zevenhoven J, Meuwissen R, Van Garderen E, Peeper DS: Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB. Nature 430: 1034–1039, 2004
Dufour G, Demers MJ, Gagne D, Dydensborg AB, Teller IC, Bouchard V, Degongre I, Beaulieu JF, Cheng JQ, Fujita N, Tsuruo T, Vallee K, Vachon PH: Human intestinal epithelial cell survival and anoikis: Differentiation state-distinct regulation and roles of protein kinase B/Akt isoforms. J Biol Chem 279: 44113–44122, 2004
Eckert LB, Repasky GA, Ulku AS, McFall A, Zhou H, Sartor CI, Der CJ: Involvement of ras activation in human breast cancer cell signaling, invasion, and anoikis. Cancer Res 64: 4585–4592, 2004
Wu C and Dedhar S: Integrin-linked kinase (ILK) and its interactors: A new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J Cell Biol 155: 505–510, 2001
Hill MM, Feng J, Hemmings BA: Identification of a plasma membrane raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1. Current Biology 12: 1251–1255, 2002
Troussard AA, Mawji NM, Ong C, Mui A, St-Arnaud R, Dedhar S: Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J Biol Chem 278: 22374–22378, 2003
Nikolopoulos SN, Turner CE: Actopaxin, a new focal adhesion protein that binds paxillin LD motifs and actin and regulates cell adhesion. J Cell Biol 151: 1435–1448, 2000
Nikolopoulos SN, Turner CE: Molecular dissection of actopaxin-integrin-linked kinase-paxillin interactions and their role in subcellular localization. J Biol Chem 277: 1568–1575, 2002
Tu Y, Huang Y, Zhang Y, Hua Y, Wu C: A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. J Cell Biol 153: 585–598, 2001
Fukuda T, Guo L, Shi X, Wu C: CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt. J Cell Biol 160: 1001–1008, 2003
Fukuda T, Chen K, Shi X, Wu C: PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. J Biol Chem 278: 51324–51333, 2003
Abbi S, Guan JL: Focal adhesion kinase: Protein interactions and cellular functions. Histol Histopathol 17: 1163–1171, 2002
Kurenova E, Xu LH, Yang X, Baldwin AS, Jr., Craven RJ, Hanks SK, Liu ZG, Cance WG: Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. Mol Cell Biol 24: 4361–4371, 2004
Hsu H, Huang J, Shu HB, Baichwal V, Goeddel DV: TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. Immunity 4: 387–396, 1996
Stanger BZ, Leder P, Lee TH, Kim E, Seed B: RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 81: 513–523, 1995
Johnson RP, Craig SW: An intramolecular association between the head and tail domains of vinculin modulates talin binding. J Biol Chem 269: 12611–12619, 1994
Johnson RP, Craig SW: F-actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 373: 261–264, 1995
Kroemker M, Rudiger AH, Jockusch BM, Rudiger M: Intramolecular interactions in vinculin control α-actinin binding to the vinculin head. FEBS Lett 355: 259–262, 1994
Coll J, Ben-Ze'ev A, Ezzell R, Fernandez J, Baribault H, Oshima R, Adamson E: Targeted disruption of vinculin genes in F9 and embryonic stem cells changes cell morphology, adhesion, and locomotion. PNAS 92: 9161–9165, 1995
Subauste MC, Pertz O, Adamson ED, Turner CE, Junger S, Hahn KM: Vinculin modulation of paxillin-fak interactions regulates erk to control survival and motility. J Cell Biol 165: 371–381, 2004
Widmann C, Gibson S, Johnson GL: Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals. J Biol Chem 273: 7141–7147, 1998
Shim SR, Kook S, Kim JI, Song WK: Degradation of focal adhesion proteins paxillin and p130Cas by caspases or calpains in apoptotic Rat-1 and L929 cells. Biochemical and Biophysical Research Communications 286: 601–608, 2001
Crouch DH, Fincham VJ, Frame MC: Targeted proteolysis of the focal adhesion kinase pp125 FAK during c-MYC-induced apoptosis is suppressed by integrin signalling. Oncogene 12: 2689–2696, 1996
Kook S, Shim SR, Choi SJ, Ahnn J, Kim JI, Eom SH, Jung YK, Paik SG, Song WK: Caspase-mediated cleavage of p130cas in etoposide-induced apoptotic Rat-1 cells. Mol Biol Cell 11: 929–939, 2000
Kim W, Kook S, Kim DJ, Teodorof C, Song WK: The 31-kDa caspase-generated cleavage product of p130Cas functions as a transcriptional repressor of E2A in apoptotic cells. J Biol Chem 279: 8333–8342, 2004
Wei L, Yang Y, Zhang X, Yu Q: Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis. J Cell Biochem 87: 439–449, 2002
O'Neill GM, Golemis EA: Proteolysis of the docking protein HEF1 and implications for focal adhesion dynamics. Mol Cell Biol 21: 5094–5108, 2001
Law SF, O'Neill GM, Fashena SJ, Einarson MB, Golemis EA: The docking protein HEF1 is an apoptotic mediator at focal adhesion sites. Mol Cell Biol 20: 5184–5195, 2000
Del Pozo MA, Kiosses WB, Alderson NB, Meller N, Hahn KM, Schwartz MA: Integrins regulate GTP-Rac localized effector interactions through dissociation of rho-gdi. Nat Cell Biol 4: 232–239, 2002
del Pozo MA, Price LS, Alderson NB, Ren XD, Schwartz MA: Adhesion to the extracellular matrix regulates the coupling of the small GTPase-Rac to its effector pak. EMBO J 19: 2008–2014, 2000
Coniglio SJ, Jou T-S, Symons M: Rac1 protects epithelial cells against anoikis. J Biol Chem 276: 28113–28120, 2001
Cheng TL, Symons M, Jou TS: Regulation of anoikis by Cdc42 and Rac1. Exp Cell Res 295: 497–511, 2004
Werner E, Werb Z: Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases. J Cell Biol 158: 357–368, 2002
Lewis JM, Truong TN, Schwartz MA: Integrins regulate the apoptotic response to DNA damage through modulation of p53. Proc Natl Acad Sci U S A 99: 3627–3632, 2002
Truong T, Sun G, Doorly M, Wang JY, Schwartz MA: Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. Proc Natl Acad Sci USA 100: 10281–10286, 2003