Claude Bernard and the heart–brain connection: Further elaboration of a model of neurovisceral integration

Ahern, 1994, Quantitative analysis of the EEG in the intracarotid amobarbital test. I. Amplitude analysis, Electroencephalography and Clinical Neurophysiology, 91, 21, 10.1016/0013-4694(94)90015-9

Ahern, 2001, Heart rate and heart rate variability changes in the intracarotid sodium amobarbital (ISA) test, Epilepsia, 42, 912, 10.1046/j.1528-1157.2001.042007912.x

Amat, 2005, Medial prefrontal cortex determines how stressor controllability affects behavior and dorsal raphe nucleus, Nature Neuroscience, 8, 365, 10.1038/nn1399

Appelhans, 2006, Heart rate variability as an index of regulated emotional responding, Review of General Psychology, 10, 229, 10.1037/1089-2680.10.3.229

Arnsten, 1998, Noise stress impairs prefrontal cortical cognitive function in monkeys: evidence for a hyperdopaminergic mechanism, Archives of General Psychiatry, 55, 362, 10.1001/archpsyc.55.4.362

Aron, 2004, Inhibition and the right inferior frontal cortex, Trends in Cognitive Sciences, 8, 170, 10.1016/j.tics.2004.02.010

Balaban, 2001, Neurological bases for balance-anxiety links, Journal of Anxiety Disorders, 15, 53, 10.1016/S0887-6185(00)00042-6

Barbas, 2003, Serial pathways from primate prefrontal cortex to autonomic areas may influence emotional expression, BMC Neuroscience, 4, 25, 10.1186/1471-2202-4-25

Barbas, 2007, The prefrontal cortex and flexible behavior, The Neuroscientist, 13, 532, 10.1177/1073858407301369

Benarroch, 1993, The central autonomic network: functional organization, dysfunction, and perspective, Mayo Clinic Proceedings, 68, 988, 10.1016/S0025-6196(12)62272-1

Benarroch, 1997, The central autonomic network, 17

Bernard, C., 1867. Lecture on the physiology of the heart and its connections with the brain, delivered at the Sorbonne, the 27th March, 1865. Tr. By J.S. Morel, Savannah, Purse.

Boomsma, 1990, Genetic influences on respiratory sinus arrhythmia across different task conditions, Acta Genetics Medical Gemellol (Roma), 39, 181, 10.1017/S0001566000005419

Brosschot, 2007, Daily worry is related to low heart rate variability during waking and the subsequent nocturnal sleep period, International Journal of Psychophysiology, 63, 39, 10.1016/j.ijpsycho.2006.07.016

Butler, 2006, Respiratory sinus arrhythmia, emotion, and emotion regulation during social interaction, Psychophysiology, 43, 612, 10.1111/j.1469-8986.2006.00467.x

Busjahn, 1998, Angiotensin-converting enzyme and angiotensinogen gene polymorphisms and heart rate variability in twins, American Journal of Cardiology, 81, 755, 10.1016/S0002-9149(97)01019-9

Cacioppo, 1999, The affect system has parallel and integrative processing components: Form follows function, Journal of Personality and Social Psychology, 76, 839, 10.1037/0022-3514.76.5.839

Chambers, 2006, Executive “brake failure” following deactivation of human frontal lobe, Journal of Cognitive Neuroscience, 18, 444

Chikazoe, 2007, Activation of right inferior frontal gyrus during response inhibition across response modalities, Journal of Cognitive Neuroscience, 19, 69, 10.1162/jocn.2007.19.1.69

Chuang, 2004, Horseradish peroxidase localization of sympathetic postganglionic and parasympathetic preganglionic neurons innervating the monkey heart, Chinese Journal of Physiology, 47, 95

Conti, 2002, Claude Bernard's Des Fontions du Creveau: an ante letteram manifesto of the neurosciences?, Nature Reviews, 3, 979, 10.1038/nrn985

Cornwell, 2006, Anticipation of public speaking in virtual reality reveals a relationship between trait social anxiety and startle reactivity, Biological Psychiatry, 59, 664, 10.1016/j.biopsych.2005.09.015

Craig, 2005, Forebrain emotional asymmetry: a neuroanatomical basis?, Trends in Cognitive Sciences, 19, 566, 10.1016/j.tics.2005.10.005

Critchley, 2003, Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence, Brain, 126, 2139, 10.1093/brain/awg216

Cunningham, 2008, Affective flexibility: evaluative processing goals shape amygdala activity, Psychological Science, 19, 152, 10.1111/j.1467-9280.2008.02061.x

Darwin, 1872

Davidson, 2000, The functional neuroanatomy of affective style, 106

Friedman, 2007, An autonomic flexibility-neurovisceral integration model of anxiety and cardiac vagal tone, Biological Psychology, 74, 185, 10.1016/j.biopsycho.2005.08.009

Friedman, 1998, Autonomic balance revisited: panic anxiety and heart rate variability, Journal of Psychosomatic Research, 44, 133, 10.1016/S0022-3999(97)00202-X

Friedman, 1998, Anxiety and autonomic flexibility: a cardiovascular approach, Biological Psychology, 48, 303

Friedman, 1993, Autonomic characteristics of nonclinical panic and blood phobia, Biological Psychiatry, 34, 298, 10.1016/0006-3223(93)90087-T

Frijda, 1988, The laws of emotion, American Psychologist, 43, 349, 10.1037/0003-066X.43.5.349

Garavan, 1999, Right hemispheric dominance of inhibitory control: an event-related functional MRI study, Proceedings of the National Academy of Sciences, 96, 8301, 10.1073/pnas.96.14.8301

Gard PR, 2002, The role of angiotensin II in cognition and behaviour, European Journal of Pharmacology, 43, 1, 10.1016/S0014-2999(02)01283-9

Gevins, 1999, Electroencephalographic imaging of higher brain function, Philosophical Transactions of the Royal Society of London B, 354, 1125, 10.1098/rstb.1999.0468

Gianaros, 2008, Brain-body pathways to cardiovascular disease risk

Gianaros, 2004, Regional cerebral blood flow correlates with heart period and high-frequency heart period variability during working-memory tasks: implications for the cortical and subcortical regulation of cardiac autonomic activity, Psychophysiology, 41, 521, 10.1111/1469-8986.2004.00179.x

Gottesman, 2003, The endophenotype concept in psychiatry: etymology and strategic intentions, American Journal of Psychiatry, 160, 636, 10.1176/appi.ajp.160.4.636

Gould, 2006, Psychiatric endophenotypes and the development of valid animal models, Genes Brain Behaviour, 5, 113, 10.1111/j.1601-183X.2005.00186.x

Grace, 2002, Regulation of conditioned responses of basolateral amygdala neurons, Physiology and Behavior, 77, 489, 10.1016/S0031-9384(02)00909-5

Hansen, 2003, Vagal Influence on working memory and attention, International Journal of Psychophysiology, 48, 263, 10.1016/S0167-8760(03)00073-4

Hansen, 2004, Heart rate variability and its relation to prefrontal cognitive function: the effects of training and detraining, European Journal of Applied Physiology, 93, 263, 10.1007/s00421-004-1208-0

Hansen, A.L., Johnsen, B.H., Thayer, J.F. Prediction of cognitive function during threat of shock. Anxiety, Stress and Coping, in press.

Hong, 2000, Contralateral EEG slowing and amobarbital distribution in Wada test: an intracarotid SPECT study, Epilepsia, 41, 207, 10.1111/j.1528-1157.2000.tb00141.x

Ingjaldsson, 2003, Reduced heart rate variability in chronic alcohol abuse: relationship with negative mood, chronic thought suppression, and compulsive drinking, Biological Psychiatry, 54, 1427, 10.1016/S0006-3223(02)01926-1

Johnsen, 2002, Heart rate variability is inversely related to cortisol reactivity during cognitive stress, Psychosomatic Medicine, 64, 289

Johnsen, 2003, Attentional and physiological characteristics of patients with dental anxiety, Journal of Anxiety Disorders, 17, 75, 10.1016/S0887-6185(02)00178-0

Jose, 1970, The normal range and determinants of the intrinsic heart rate in man, Cardiovascular Research, 4, 160, 10.1093/cvr/4.2.160

Kalisch, 2005, Anxiety reduction through detachment: subjective, physiological, and neural effects, Journal of Cognitive Neuroscience, 17, 874, 10.1162/0898929054021184

Knight, 1999, Prefrontal cortex regulates inhibition and excitation in distributed neural networks, Acta Psychologica, 101, 159, 10.1016/S0001-6918(99)00004-9

Konishi, 1999, Common inhibitory mechanism in human inferior prefrontal cortex revealed by event-related functional MRI, Brain, 122, 981, 10.1093/brain/122.5.981

Kupper, 2004, Heritability of ambulatory heart rate variability, Circulation, 110, 2792, 10.1161/01.CIR.0000146334.96820.6E

Lane, 2008, Neural substrates of implicit and explicit emotional processes: a unifying framework for psychosomatic medicine, Psychosomatic Medicine, 70, 213, 10.1097/PSY.0b013e3181647e44

Lane, 2007, Neural correlates of vagal tone during emotion, Psychosomatic Medicine, 69, A-8

Lane, 2001, Activity in medial prefrontal cortex correlates with vagal component of heart rate variability during emotion, Brain and Cognition, 47, 97

Lane, R.D., McRae, K., Reiman, E.M., Chen, K., Ahern, G.L., Thayer, J.F. Neural correlates of heart rate variability during emotion. Neuroimage, in press.

Lane, 2008, Subgenual anterior cingulate (BA25) activity covaries with changes in cardiac vagal tone during affective set shifting in healthy adults, Psychosomatic Medicine, 70, A-42

LeDoux, 1996

Levy, 1990, Autonomic interactions in cardiac control, Annals of the New York Academy of Sciences, 601, 209, 10.1111/j.1749-6632.1990.tb37302.x

Liao, 2002, Lower heart rate variability is associated with the development of coronary heart disease in patients with diabetes—the atherosclerosis risk in communities (ARIC) study, Diabetes, 51, 3524, 10.2337/diabetes.51.12.3524

Lieberman, 2007, Putting feelings into words: affect labeling disrupts amygdala activity in response to affective stimuli, Psychological Science, 18, 421, 10.1111/j.1467-9280.2007.01916.x

McEwen, 1998, Protective and damaging effects of stress mediators, New England Journal of Medicine, 338, 171, 10.1056/NEJM199801153380307

Melzig C.A., Hamm A.O., Thayer J.F. Individual differences in fear-potentiated startle as a function of resting heart rate variability: implications for panic disorder. International Journal of Psychophysiology, in press.

Nagai, 2004, Activity in the ventromedial prefrontal cortex covaries with sympathetic skin conductance level: a physiological account of a “default mode” of brain function, Neuroimage, 22, 243, 10.1016/j.neuroimage.2004.01.019

Neumann, 2005, Heart rate variability is associated with polymorphic variation in the choline transporter gene, Psychosomatic Medicine, 67, 168, 10.1097/01.psy.0000155671.90861.c2

Nugent, 2007, Anatomical correlates of autonomic control during a motor task, Psychosomatic Medicine, 69, A-74

Nugent, 2008, Alterations in neural correlates of autonomic control in females with major depressive disorder, Psychosomatic Medicine, 70, A-99

Ojemann, 2002, The frontal lobe role in memory: a review of convergent evidence and implications for the Wada memory test, Epilepsy and Behavior, 3, 309, 10.1016/S1525-5050(02)00039-2

Olsson, 2004, Angiotensin-related genes in patients with panic disorder, American Journal of Medicine Genetics B Neuropsychiatric Genetics, 127, 81, 10.1002/ajmg.b.20164

Raichle, 2001, A default mode of brain function, Proceedings of the National Academy of Science, 16, 676, 10.1073/pnas.98.2.676

Rempel-Clower, 2007, Role of orbitofrontal cortex connections in emotion, Annals of the New York Academy of Sciences, 1121, 72, 10.1196/annals.1401.026

Resstel, 2006, Involvement of the medial prefrontal cortex in central cardiovascular modulation in the rat, Autonomic Neuroscience: Basic and Clinical, 126–127, 130, 10.1016/j.autneu.2006.02.022

Ruiz-Padial, 2003, The rhythm of the heart in the blink of an eye: emotion-modulated startle magnitude covaries with heart rate variability, Psychophysiology, 40, 306, 10.1111/1469-8986.00032

Saha, 2005, Role of the central nucleus of the amygdala in the control of blood pressure: Descending pathways to medullary cardiovascular nuclei, Clinical and Experimental Pharmacology and Physiology, 32, 450, 10.1111/j.1440-1681.2005.04210.x

Saha, 2000, GABAergic projection from the central nucleus of the amygdala to the nucleus of the solitary tract: a combined anterograde tracing and electron microscopic immunohistochemical study, Neuroscience, 99, 613, 10.1016/S0306-4522(00)00240-2

Saus, 2006, The effect of brief situational awareness training in a police shooting simulator: an experimental study, Military Psychology, 3, 10.1207/s15327876mp1803s_2

Shekhar, 2003, The amygdala, panic disorder, and cardiovascular responses, Annals of the New York Academy of Sciences, 985, 308, 10.1111/j.1749-6632.2003.tb07090.x

Shook, 2007, Negativity bias in attitude learning: a possible indicator of vulnerability to emotional disorders?, Journal of Behavior Therapy and Experimental Psychiatry, 38, 144, 10.1016/j.jbtep.2006.10.005

Shook, 2007, Friend or foe: heart rate variability and the negativity bias in learning about novel objects, Psychophysiology, 44, S39

Snieder, 2007, Sex differences and heritability of two indices of heart rate dynamics: a twin study, Twin Research of Human Genetics, 10, 364, 10.1375/twin.10.2.364

Spyer, 1994, Central nervous mechanisms contributing to cardiovascular control, Journal of Physiology, 474, 1, 10.1113/jphysiol.1994.sp019997

Srinivasan, 2002, Decreased chaos of heart rate time series in children of patients with panic disorder, Depression and Anxiety, 15, 159, 10.1002/da.10046

Ter Horst, 1999, Central autonomic control of the heart, angina, and pathogenic mechanisms of post-myocardial infarction depression, European Journal of Morphology, 37, 257, 10.1076/ejom.37.4.257.4722

Ter Horst, 1997, Forebrain parasympathetic control of heart activity: retrograde transneuronal viral labeling in rats, American Journal of Physiology, 273, H2926

Thayer, 2006, On the importance of inhibition: central and peripheral manifestations of nonlinear inhibitory processes in neural systems, Dose-Response (formerly Nonlinearity in Biology, Toxicology, and Medicine), 4, 2

Thayer, 2005, Psychosomatics and psychopathology: looking up and down from the brain, Psychoneuroendocrinology, 30, 1050, 10.1016/j.psyneuen.2005.04.014

Thayer, 2005, Evidence for the cholinergic anti-inflammatory pathway in healthy human adults, Psychosomatic Medicine, 67, S8

Thayer, 2004, A neurovisceral integration model of health disparities in aging, 567

Thayer, 2005, Heart rate variability as an index of prefrontal neural function in military settings, Biomonitoring for Physiological and Cognitive Performance During Military Operations, Proceedings of SPIE, 5797, 71, 10.1117/12.604420

Thayer, J.F., Johnsen, B.H., 2004. Autonomic nervous system activity and its relationship to attention and working memory. Committee on Metabolic Monitoring for Military Field Applications, Vanderveen J (chair), Monitoring Metabolic Status: Predicting Decrements in Physiological and Cognitive Performance. The National Academies Press, Washington, DC, pp. 366–371.

Thayer, 2000, A model of neurovisceral integration in emotion regulation and dysregulation, Journal of Affective Disorders, 61, 201, 10.1016/S0165-0327(00)00338-4

Thayer, 2005, The importance of inhibition in dynamical systems models of emotion and neurobiology, Brain and Behavioral Sciences, 28, 218, 10.1017/S0140525X05470041

Thayer, 2007, The role of vagal function in the risk for cardiovascular disease and mortality, Biological Psychology, 74, 224, 10.1016/j.biopsycho.2005.11.013

Thayer, 2003, Effect of angiotensin-converting enzyme insertion/deletion polymorphism DD genotype on high-frequency heart rate variability in African Americans, American Journal of Cardiology, 92, 1487, 10.1016/j.amjcard.2003.08.069

Thayer, 2006, Beyond heart rate variability: vagal regulation of allostatic systems, Annals of the New York Academy of Sciences, 1088, 361, 10.1196/annals.1366.014

Uijtdehagge, 2000, Accentuated antagonism in the control of human heart rate, Clinical Autonomic Research, 10, 107, 10.1007/BF02278013

Wang, X., Ding, X., Su, S., Li, Z., Riese, H., Thayer, J.F., Treiber, F., Snieder, H. Genetic influences on heart rate variability at rest and during stress. Psychophysiology, in press.

Wang, 2005, Ethnic differences and heritability of heart rate variability in African- and European American youth, American Journal of Cardiology, 96, 1166, 10.1016/j.amjcard.2005.06.050

Williams, 2006, Mode of functional connectivity in amygdala pathways dissociates level of awareness for signals of fear, Journal of Neuroscience, 26, 9264, 10.1523/JNEUROSCI.1016-06.2006

Wong, 2007, Ventral medial prefrontal cortex and cardiovagal control in conscious humans, Neuroimage, 35, 698, 10.1016/j.neuroimage.2006.12.027