Classification and definition of major flares in SLE clinical trials

Lupus - Tập 8 Số 8 - Trang 685-691 - 1999
Michelle Petri1, Jill P. Buyon2, Mimi Kim3
1Division of Rheumatology, Johns Hopkins University School of Medicine, 1830 E Monument Street, Suite 7500, Baltimore, MD 21205, USA; Fax: (+1) 410 614 0498;
2Hospital for Joint Diseases New York USA
3Department of Environmental Medicine, New York Medical Center, New York, USA

Tóm tắt

Multiple reliable and valid disease activities indices exist and have been used successfully in longitudinal studies. However, the definition of flare, using these intruments, has not been universally decided or accepted. Because flare is one of the three major patterns of lupus activity, it will remain an important outcome measure in both longitudinal and clinical trial studies.

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