Circuit-Selective Striatal Synaptic Dysfunction in the Sapap3 Knockout Mouse Model of Obsessive-Compulsive Disorder

Biological Psychiatry - Tập 75 - Trang 623-630 - 2014
Yehong Wan1, Kristen K. Ade1, Zachary Caffall1, M. Ilcim Ozlu2, Cagla Eroglu3,2, Guoping Feng4, Nicole Calakos1,3
1Department of Medicine, Division of Neurology, Durham, North Carolina
2Department of Cell Biology, Duke University, Durham, North Carolina
3Department of Neurobiology, Durham, North Carolina
4Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts

Tài liệu tham khảo

Kim, 1997, GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules, J Cell Biol, 136, 669, 10.1083/jcb.136.3.669 Takeuchi, 1997, SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density, J Biol Chem, 272, 11943, 10.1074/jbc.272.18.11943 Welch, 2004, Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse, J Comp Neurol, 472, 24, 10.1002/cne.20060 Kim, 2004, PDZ domain proteins of synapses, Nat Rev Neurosci, 5, 771, 10.1038/nrn1517 Chen, 2011, Sapap3 deletion anomalously activates short-term endocannabinoid-mediated synaptic plasticity, J Neurosci, 31, 9563, 10.1523/JNEUROSCI.1701-11.2011 Wan, 2011, Sapap3 deletion causes mGluR5-dependent silencing of AMPAR synapses, J Neurosci, 31, 16685, 10.1523/JNEUROSCI.2533-11.2011 Welch, 2007, Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice, Nature, 448, 894, 10.1038/nature06104 Boardman, 2011, Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population, Compr Psychiatry, 52, 181, 10.1016/j.comppsych.2010.05.007 Ryu, 2011, Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms, Am J Med Genet B Neuropsychiatr Genet, 156B, 949, 10.1002/ajmg.b.31242 Zuchner, 2009, Multiple rare SAPAP3 missense variants in trichotillomania and OCD, Mol Psychiatry, 14, 6, 10.1038/mp.2008.83 Friedlander, 2006, Neuroimaging studies of obsessive-compulsive disorder in adults and children, Clin Psychol Rev, 26, 32, 10.1016/j.cpr.2005.06.010 Pennartz, 2009, Corticostriatal interactions during learning, memory processing, and decision making, J Neurosci, 29, 12831, 10.1523/JNEUROSCI.3177-09.2009 Smith, 2011, Thalamic contributions to basal ganglia-related behavioral switching and reinforcement, J Neurosci, 31, 16102, 10.1523/JNEUROSCI.4634-11.2011 Ding, 2008, Corticostriatal and thalamostriatal synapses have distinctive properties, J Neurosci, 28, 6483, 10.1523/JNEUROSCI.0435-08.2008 Dube, 1988, Identification of synaptic terminals of thalamic or cortical origin in contact with distinct medium-size spiny neurons in the rat neostriatum, J Comp Neurol, 267, 455, 10.1002/cne.902670402 Smeal, 2007, A rat brain slice preparation for characterizing both thalamostriatal and corticostriatal afferents, J Neurosci Methods, 159, 224, 10.1016/j.jneumeth.2006.07.007 Smith, 2004, The thalamostriatal system: A highly specific network of the basal ganglia circuitry, Trends Neurosci, 27, 520, 10.1016/j.tins.2004.07.004 Villalba, 2011, Differential structural plasticity of corticostriatal and thalamostriatal axo-spinous synapses in MPTP-treated Parkinsonian monkeys, J Comp Neurol, 519, 989, 10.1002/cne.22563 Gong, 2003, A gene expression atlas of the central nervous system based on bacterial artificial chromosomes, Nature, 425, 917, 10.1038/nature02033 Shuen, 2008, Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia, J Neurosci, 28, 2681, 10.1523/JNEUROSCI.5492-07.2008 Gerfen, 1992, The neostriatal mosaic: Multiple levels of compartmental organization in the basal ganglia, Annu Rev Neurosci, 15, 285, 10.1146/annurev.ne.15.030192.001441 Kreitzer, 2008, Striatal plasticity and basal ganglia circuit function, Neuron, 60, 543, 10.1016/j.neuron.2008.11.005 Ippolito, 2010, Quantifying synapses: An immunocytochemistry-based assay to quantify synapse number, J Vis Exp, 45, 2270 Goda, 1994, Two components of transmitter release at a central synapse, Proc Natl Acad Sci U S A, 91, 12942, 10.1073/pnas.91.26.12942 Fujiyama, 2004, Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals, Eur J Neurosci, 20, 3322, 10.1111/j.1460-9568.2004.03807.x Kaneko, 2002, Immunohistochemical localization of candidates for vesicular glutamate transporters in the rat brain, J Comp Neurol, 444, 39, 10.1002/cne.10129 Barroso-Chinea, 2008, Expression of vesicular glutamate transporters 1 and 2 in the cells of origin of the rat thalamostriatal pathway, J Chem Neuroanat, 35, 101, 10.1016/j.jchemneu.2007.08.001 Barroso-Chinea, 2007, Expression of the mRNAs encoding for the vesicular glutamate transporters 1 and 2 in the rat thalamus, J Comp Neurol, 501, 703, 10.1002/cne.21265 Graziano, 2008, Vesicular glutamate transporters define two sets of glutamatergic afferents to the somatosensory thalamus and two thalamocortical projections in the mouse, J Comp Neurol, 507, 1258, 10.1002/cne.21592 Rubio, 1997, Glutamate receptors are selectively targeted to postsynaptic sites in neurons, Neuron, 18, 939, 10.1016/S0896-6273(00)80333-5 Toth, 1998, Afferent-specific innervation of two distinct AMPA receptor subtypes on single hippocampal interneurons, Nat Neurosci, 1, 572, 10.1038/2807 Doig, 2010, Cortical and thalamic innervation of direct and indirect pathway medium-sized spiny neurons in mouse striatum, J Neurosci, 30, 14610, 10.1523/JNEUROSCI.1623-10.2010 de Koning, 2011, Current status of deep brain stimulation for obsessive-compulsive disorder: A clinical review of different targets, Curr Psychiatry Rep, 13, 274, 10.1007/s11920-011-0200-8 Albelda, 2012, Current animal models of obsessive compulsive disorder: An update, Neuroscience, 211, 83, 10.1016/j.neuroscience.2011.08.070 Blundell, 2010, Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior, J Neurosci, 30, 2115, 10.1523/JNEUROSCI.4517-09.2010 Peca, 2011, Shank3 mutant mice display autistic-like behaviours and striatal dysfunction, Nature, 472, 437, 10.1038/nature09965 Shmelkov, 2010, Slitrk5 deficiency impairs corticostriatal circuitry and leads to obsessive-compulsive-like behaviors in mice, Nat Med, 16, 598, 10.1038/nm.2125