Circadian proteins in the regulation of cell cycle and genotoxic stress responses

Ko, 2006, Molecular components of the mammalian circadian clock, Hum. Mol. Genet., 15, R271, 10.1093/hmg/ddl207 Kondratov, 2007, The role of mammalian circadian proteins in normal physiology and genotoxic stress responses, Curr. Top. Dev. Biol., 78, 173, 10.1016/S0070-2153(06)78005-X Stratmann, 2006, Properties, entrainment, and physiological functions of mammalian peripheral oscillators, J. Biol. Rhythms, 21, 494, 10.1177/0748730406293889 Gachon, 2006, The circadian PAR-domain basic leucine zipper transcription factors DBP, TEF, and HLF modulate basal and inducible xenobiotic detoxification, Cell Metab., 4, 25, 10.1016/j.cmet.2006.04.015 Panda, 2002, Coordinated transcription of key pathways in the mouse by the circadian clock, Cell, 109, 307, 10.1016/S0092-8674(02)00722-5 Cardone, 2005, Circadian clock control by SUMOylation of BMAL1, Science, 309, 1390, 10.1126/science.1110689 Lee, 2001, Posttranslational mechanisms regulate the mammalian circadian clock, Cell, 107, 855, 10.1016/S0092-8674(01)00610-9 Kondratov, 2003, BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock system, Genes Dev., 17, 1921, 10.1101/gad.1099503 Akashi, 2002, Control of intracellular dynamics of mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in cultured cells, Mol. Cell. Biol., 22, 1693, 10.1128/MCB.22.6.1693-1703.2002 Eide, 2005, Control of mammalian circadian rhythm by CKIepsilon-regulated proteasome-mediated PER2 degradation, Mol. Cell. Biol., 25, 2795, 10.1128/MCB.25.7.2795-2807.2005 Tamanini, 2005, Nucleocytoplasmic shuttling of clock proteins, Methods Enzymol., 393, 418, 10.1016/S0076-6879(05)93020-6 Akhtar, 2002, Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus, Curr. Biol., 12, 540, 10.1016/S0960-9822(02)00759-5 Storch, 2002, Extensive and divergent circadian gene expression in liver and heart, Nature, 417, 78, 10.1038/nature744 Duffield, 2002, Circadian programs of transcriptional activation, signaling, and protein turnover revealed by microarray analysis of mammalian cells, Curr. Biol., 12, 551, 10.1016/S0960-9822(02)00765-0 Levi, 2007, Circadian rhythms: mechanisms and therapeutic implications, Annu. Rev. Pharmacol. Toxicol., 47, 593, 10.1146/annurev.pharmtox.47.120505.105208 Bjarnason, 2001, Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases, Am. J. Pathol., 158, 1793, 10.1016/S0002-9440(10)64135-1 Fu, 2002, The circadian gene Period2 plays an important role in tumor suppression and DNA damage response in vivo, Cell, 111, 41, 10.1016/S0092-8674(02)00961-3 Matsuo, 2003, Control mechanism of the circadian clock for timing of cell division in vivo, Science, 302, 255, 10.1126/science.1086271 Gauger, 2005, Cryptochrome, circadian cycle, cell cycle checkpoints, and cancer, Cancer Res., 65, 6828, 10.1158/0008-5472.CAN-05-1119 Miller, 2007, Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation, Proc. Natl. Acad. Sci. U. S. A., 104, 3342, 10.1073/pnas.0611724104 Kondratov, 2006, Dual role of the CLOCK/BMAL1 circadian complex in transcriptional regulation, FASEB J., 20, 530, 10.1096/fj.05-5321fje Haus, 2001, Circadian rhythms of basic fibroblast growth factor (bFGF), epidermal growth factor (EGF), insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), cortisol, and melatonin in women with breast cancer, Chronobiol. Int., 18, 709, 10.1081/CBI-100106083 Holzheimer, 2002, Circadian rhythm of cytokine secretion following thermal injury in mice: implications for burn and trauma research, Shock, 17, 527, 10.1097/00024382-200206000-00015 Antoch, 2005, Circadian clock genes as modulators of sensitivity to genotoxic stress, Cell Cycle, 4, 901, 10.4161/cc.4.7.1792 Fu, 2003, The circadian clock: pacemaker and tumour suppressor, Nat. Rev. Cancer, 3, 350, 10.1038/nrc1072 Bae, 2001, Differential functions of mPer1, mPer2, and mPer3 in the SCN circadian clock, Neuron, 30, 525, 10.1016/S0896-6273(01)00302-6 Zheng, 2001, Nonredundant roles of the mPer1 and mPer2 genes in the mammalian circadian clock, Cell, 105, 683, 10.1016/S0092-8674(01)00380-4 Shearman, 2000, Targeted disruption of the mPer3 gene: subtle effects on circadian clock function, Mol. Cell. Biol., 20, 6269, 10.1128/MCB.20.17.6269-6275.2000 Lee, 1999, PER and TIM inhibit the DNA binding activity of a Drosophila CLOCK-CYC/dBMAL1 heterodimer without disrupting formation of the heterodimer: a basis for circadian transcription, Mol. Cell. Biol., 19, 5316, 10.1128/MCB.19.8.5316 Gery, 2006, The circadian gene per1 plays an important role in cell growth and DNA damage control in human cancer cells, Mol. Cell, 22, 375, 10.1016/j.molcel.2006.03.038 Koike, 1998, Identification of the mammalian homologues of the Drosophila timeless gene, Timeless1, FEBS Lett., 441, 427, 10.1016/S0014-5793(98)01597-X Sangoram, 1998, Mammalian circadian autoregulatory loop: a timeless ortholog and mPer1 interact and negatively regulate CLOCK-BMAL1-induced transcription, Neuron, 21, 1101, 10.1016/S0896-6273(00)80627-3 Takumi, 1999, A mammalian ortholog of Drosophila timeless, highly expressed in SCN and retina, forms a complex with mPER1, Genes Cells, 4, 67, 10.1046/j.1365-2443.1999.00238.x Zylka, 1998, Molecular analysis of mammalian timeless, Neuron, 21, 1115, 10.1016/S0896-6273(00)80628-5 Hardin, 2005, The circadian timekeeping system of Drosophila, Curr. Biol., 15, R714, 10.1016/j.cub.2005.08.019 Gotter, 2006, A Timeless debate: resolving TIM's noncircadian roles with possible clock function, Neuroreport, 17, 1229, 10.1097/01.wnr.0000233092.90160.92 Barnes, 2003, Requirement of mammalian Timeless for circadian rhythmicity, Science, 302, 439, 10.1126/science.1086593 Field, 2000, Analysis of clock proteins in mouse SCN demonstrates phylogenetic divergence of the circadian clockwork and resetting mechanisms, Neuron, 25, 437, 10.1016/S0896-6273(00)80906-X Gotter, 2003, Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association, J. Mol. Biol., 331, 167, 10.1016/S0022-2836(03)00633-8 Gotter, 2000, A time-less function for mouse timeless, Nat. Neurosci., 3, 755, 10.1038/77653 Unsal-Kacmaz, 2005, Coupling of human circadian and cell cycles by the timeless protein, Mol. Cell. Biol., 25, 3109, 10.1128/MCB.25.8.3109-3116.2005 Chou, 2006, Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function, Proc. Natl. Acad. Sci. U. S. A., 103, 18143, 10.1073/pnas.0609251103 Unsal-Kacmaz, 2007, The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement, Mol. Cell. Biol., 27, 3131, 10.1128/MCB.02190-06 Yoshizawa-Sugata, 2007, Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint, J. Biol. Chem., 282, 2729, 10.1074/jbc.M605596200 Gotter, 2007, Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors, J. Mol. Biol., 366, 36, 10.1016/j.jmb.2006.10.097 Lupardus, 2002, A requirement for replication in activation of the ATR-dependent DNA damage checkpoint, Genes Dev., 16, 2327, 10.1101/gad.1013502 Kumagai, 2000, Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts, Mol. Cell, 6, 839, 10.1016/S1097-2765(05)00092-4 Lee, 2005, Roles of replication fork-interacting and Chk1-activating domains from Claspin in a DNA replication checkpoint response, Mol. Biol. Cell, 16, 5269, 10.1091/mbc.E05-07-0671 Dalgaard, 2000, swi1 and swi3 perform imprinting, pausing, and termination of DNA replication in S. pombe, Cell, 102, 745, 10.1016/S0092-8674(00)00063-5 Foss, 2001, Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae, Genetics, 157, 567, 10.1093/genetics/157.2.567 Chan, 2003, Chromosome cohesion is regulated by a clock gene paralogue TIM-1, Nature, 423, 1002, 10.1038/nature01697 Pregueiro, 2006, The Neurospora checkpoint kinase 2: a regulatory link between the circadian and cell cycles, Science, 313, 644, 10.1126/science.1121716 Kondratov, 2006, Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock, Genes Dev., 20, 1868, 10.1101/gad.1432206 Curtis, 2006, Central and peripheral clocks in cardiovascular and metabolic function, Ann. Med., 38, 552, 10.1080/07853890600995010 Gorbacheva, 2005, Circadian sensitivity to the chemotherapeutic agent cyclophosphamide depends on the functional status of the CLOCK/BMAL1 transactivation complex, Proc. Natl. Acad. Sci. U. S. A., 102, 3407, 10.1073/pnas.0409897102 Harrison, 2006, Surviving the breakup: the DNA damage checkpoint, Annu. Rev. Genet., 40, 209, 10.1146/annurev.genet.40.051206.105231 Guillaumond, 2005, Differential control of Bmal1 circadian transcription by REV-ERB and ROR nuclear receptors, J. Biol. Rhythms, 20, 391, 10.1177/0748730405277232