Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
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For the preparation of 1-(4-fluoro-3-chlorophenyl)piperazine (20f) see: D.J. O'Neill, E. Saiah, S.W.A. Kang, A. Brearley, J. Bentley. Pyrrole mTORC Inhibitors and Uses Thereof. WO/2018/089493.
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