Chronic traumatic encephalopathy: fluid biomarkers

Alosco, 2017, Repetitive head impact exposure and later-life plasma total tau in former National Football League players, Alzheimers Dement (Amst), 7, 33, 10.1016/j.dadm.2016.11.003 Alosco M, Tripodis Y, Fritts NG, et al. (in press). Cerebrospinal fluid tau, Aβ, and sTREM2 in former national football league players: modeling the relationship between repetitive head impacts, microglial activation, and neurodegeneration. Alzheimers Dement. Apweiler, 2009, Approaching clinical proteomics: current state and future fields of application in fluid proteomics, Clin Chem Lab Med, 47, 724, 10.1515/CCLM.2009.167 Babcock, 2013, Inability of S100B to predict postconcussion syndrome in children who present to the emergency department with mild traumatic brain injury: a brief report, Pediatr Emerg Care, 29, 458, 10.1097/PEC.0b013e31828a202d Blennow, 2010, Cerebrospinal fluid and plasma biomarkers in Alzheimer disease, Nat Rev Neurol, 6, 131, 10.1038/nrneurol.2010.4 Blennow, 2016, Traumatic brain injuries, Nat Rev Dis Primers, 2, 16084, 10.1038/nrdp.2016.84 Bogoslovsky, 2017, Increases of plasma levels of glial fibrillary acidic protein, tau, and amyloid beta up to 90 days after traumatic brain injury, J Neurotrauma, 34, 66, 10.1089/neu.2015.4333 Bolstad, 2013, Heterophilic antibody interference in immunometric assays, Best Pract Res Clin Endocrinol Metab, 27, 647, 10.1016/j.beem.2013.05.011 Broshek, 2015, A review of post-concussion syndrome and psychological factors associated with concussion, Brain Inj, 29, 228, 10.3109/02699052.2014.974674 Chen, 2016, Multiplex analyte assays to characterize different dementias: brain inflammatory cytokines in poststroke and other dementias, Neurobiol Aging, 38, 56, 10.1016/j.neurobiolaging.2015.10.021 Cherry, 2016, Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy, Acta Neuropathol Commun, 4, 112, 10.1186/s40478-016-0382-8 Corsellis, 1973, The aftermath of boxing, Psychol Med, 3, 270, 10.1017/S0033291700049588 Czeiter, 2012, Brain injury biomarkers may improve the predictive power of the IMPACT outcome calculator, J Neurotrauma, 29, 1770, 10.1089/neu.2011.2127 DeKosky, 2013, Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers, Nat Rev Neurol, 9, 192, 10.1038/nrneurol.2013.36 Devic, 2011, Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease, Brain, 134, 10.1093/brain/awr015 Duits, 2016, Performance and complications of lumbar puncture in memory clinics: Results of the multicenter lumbar puncture feasibility study, Alzheimers Dement, 12, 154, 10.1016/j.jalz.2015.08.003 Eisenberg, 2013, Time interval between concussions and symptom duration, Pediatrics, 132, 8, 10.1542/peds.2013-0432 Farkas, 2005, Spectrin breakdown products in the cerebrospinal fluid in severe head injury – preliminary observations, Acta Neurochir (Wien), 147, 855, 10.1007/s00701-005-0559-6 Friede, 1970, Axon caliber related to neurofilaments and microtubules in sciatic nerve fibers of rats and mice, Anat Rec, 167, 379, 10.1002/ar.1091670402 Gatson, 2014, Detection of neurofilament-H in serum as a diagnostic tool to predict injury severity in patients who have suffered mild traumatic brain injury, J Neurosurg, 121, 1232, 10.3171/2014.7.JNS132474 Ghidoni, 2018, Innovative biomarkers for Alzheimer's disease: Focus on the hidden disease biomarkers, J Alzheimers Dis., 62, 1507, 10.3233/JAD-170953 Gisslen, 2016, Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: a cross-sectional study, EBioMedicine, 3, 135, 10.1016/j.ebiom.2015.11.036 Hampel, 2004, Measurement of phosphorylated tau epitopes in the differential diagnosis of Alzheimer disease: a comparative cerebrospinal fluid study, Arch Gen Psychiatry, 61, 95, 10.1001/archpsyc.61.1.95 Heslegrave, 2016, Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer's disease, Mol Neurodegener, 11, 3, 10.1186/s13024-016-0071-x Iliff, 2012, A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta, Sci Transl Med, 4, 10.1126/scitranslmed.3003748 Iverson, 2015, A critical review of chronic traumatic encephalopathy, Neurosci Biobehav Rev, 56, 276, 10.1016/j.neubiorev.2015.05.008 Johanson, 2008, Multiplicity of cerebrospinal fluid functions: New challenges in health and disease, Cerebrospinal Fluid Res, 5, 10, 10.1186/1743-8454-5-10 Kricka, 1999, Human anti-animal antibody interferences in immunological assays, Clin Chem, 45, 942, 10.1093/clinchem/45.7.942 Kuhle, 2016, Comparison of three analytical platforms for quantification of the neurofilament light chain in blood samples: ELISA, electrochemiluminescence immunoassay and Simoa, Clin Chem Lab Med, 54, 1655, 10.1515/cclm-2015-1195 Levin, 2015, Diagnosis, prognosis, and clinical management of mild traumatic brain injury, Lancet Neurol, 14, 506, 10.1016/S1474-4422(15)00002-2 Ling, 2015, Neurological consequences of traumatic brain injuries in sports, Mol Cell Neurosci, 66, 114, 10.1016/j.mcn.2015.03.012 Ling, 2017, Mixed pathologies including chronic traumatic encephalopathy account for dementia in retired association football (soccer) players, Acta Neuropathol, 133, 337, 10.1007/s00401-017-1680-3 Losoi, 2016, Recovery from mild traumatic brain injury in previously healthy adults, J Neurotrauma, 33, 766, 10.1089/neu.2015.4070 Louveau, 2015, Structural and functional features of central nervous system lymphatic vessels, Nature, 523, 337, 10.1038/nature14432 Lundberg, 2011, Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood, Nucleic Acids Res, 39, 10.1093/nar/gkr424 Mattsson, 2016, Plasma tau in Alzheimer disease, Neurology, 87, 1827, 10.1212/WNL.0000000000003246 McCrory, 2009, Consensus statement on concussion in sport - the Third International Conference on Concussion in Sport held in Zurich, November 2008, Phys Sportsmed, 37, 141, 10.3810/psm.2009.06.1721 McKee, 2010, TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy, J Neuropathol Exp Neurol, 69, 918, 10.1097/NEN.0b013e3181ee7d85 McKee, 2013, The spectrum of disease in chronic traumatic encephalopathy, Brain, 136, 43, 10.1093/brain/aws307 McKee, 2016, The first NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy, Acta Neuropathol, 131, 75, 10.1007/s00401-015-1515-z McMahon, 2015, Measurement of the GFAP-BDP biomarker for the detection of traumatic brain injury compared to CT and MRI, J Neurotrauma, 32, 527, 10.1089/neu.2014.3635 Mondello, 2010, alphaII-spectrin breakdown products (SBDPs): diagnosis and outcome in severe traumatic brain injury patients, J Neurotrauma, 27, 1203, 10.1089/neu.2010.1278 Montenigro, 2014, Clinical subtypes of chronic traumatic encephalopathy: literature review and proposed research diagnostic criteria for traumatic encephalopathy syndrome, Alzheimers Res Ther, 6, 68, 10.1186/s13195-014-0068-z Morris, 2011, The many faces of tau, Neuron, 70, 410, 10.1016/j.neuron.2011.04.009 Neselius, 2012, CSF-biomarkers in Olympic boxing: diagnosis and effects of repetitive head trauma, PLoS ONE, 7, 10.1371/journal.pone.0033606 Neselius, 2013, Increased CSF levels of phosphorylated neurofilament heavy protein following bout in amateur boxers, PLoS ONE, 8, 10.1371/journal.pone.0081249 Oliver, 2016, Serum neurofilament light in American football athletes over the course of a season, J Neurotrauma, 33, 1784, 10.1089/neu.2015.4295 Olivera, 2015, Peripheral total tau in military personnel who sustain traumatic brain injuries during deployment, JAMA Neurol, 72, 1109, 10.1001/jamaneurol.2015.1383 Olsson, 2011, Biomarker-based dissection of neurodegenerative diseases, Prog Neurobiol, 95, 520, 10.1016/j.pneurobio.2011.04.006 Papa, 2014, GFAP out-performs S100beta in detecting traumatic intracranial lesions on computed tomography in trauma patients with mild traumatic brain injury and those with extracranial lesions, J Neurotrauma, 31, 1815, 10.1089/neu.2013.3245 Pike, 2001, Accumulation of non-erythroid alpha II-spectrin and calpain-cleaved alpha II-spectrin breakdown products in cerebrospinal fluid after traumatic brain injury in rats, J Neurochem, 78, 1297, 10.1046/j.1471-4159.2001.00510.x Pineda, 2007, Clinical significance of alphaII-spectrin breakdown products in cerebrospinal fluid after severe traumatic brain injury, J Neurotrauma, 24, 354, 10.1089/neu.2006.003789 Plog, 2015, Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system, J Neurosci, 35, 518, 10.1523/JNEUROSCI.3742-14.2015 Portelius, 2017, Ex vivo 18O-labeling mass spectrometry identifies a peripheral amyloid β clearance pathway, Mol Neurodegener, 12, 18, 10.1186/s13024-017-0152-5 Posti, 2017, Glial fibrillary acidic protein and ubiquitin C-terminal hydrolase-L1 are not specific biomarkers for mild CT-negative traumatic brain injury, J Neurotrauma, 10.1089/neu.2016.4442 Randall, 2013, Tau proteins in serum predict neurological outcome after hypoxic brain injury from cardiac arrest: results of a pilot study, Resuscitation, 84, 351, 10.1016/j.resuscitation.2012.07.027 Rissin, 2010, Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations, Nat Biotechnol, 28, 595, 10.1038/nbt.1641 Schmidt, 2001, Tau isoform profile and phosphorylation state in dementia pugilistica recapitulate Alzheimer's disease, Acta Neuropathol, 101, 518, 10.1007/s004010000330 Schulte, 2015, Utilization of the clinical laboratory for the implementation of concussion biomarkers in collegiate football and the necessity of personalized and predictive athlete specific reference intervals, EPMA J, 7, 1, 10.1186/s13167-016-0050-x Shahim, 2014, Blood biomarkers for brain injury in concussed professional ice hockey players, JAMA Neurol, 71, 684, 10.1001/jamaneurol.2014.367 Shahim, 2016, Serum neurofilament light protein predicts clinical outcome in traumatic brain injury, Sci Rep, 6, 36791, 10.1038/srep36791 Shahim, 2017, Astroglial activation and altered amyloid metabolism in human repetitive concussion, Neurology, 88, 1400, 10.1212/WNL.0000000000003816 Shahim, 2017, Serum neurofilament light as a biomarker for mild traumatic brain injury in contact sports, Neurology, 88, 1788, 10.1212/WNL.0000000000003912 Shi, 2011, Salivary tau species are potential biomarkers of Alzheimer's disease, J Alzheimers Dis, 27, 299, 10.3233/JAD-2011-110731 Shively, 2016, Characterisation of interface astroglial scarring in the human brain after blast exposure: a post-mortem case series, Lancet Neurol, 15, 944, 10.1016/S1474-4422(16)30057-6 Siman, 2009, A panel of neuron-enriched proteins as markers for traumatic brain injury in humans, J Neurotrauma, 26, 1867, 10.1089/neu.2009.0882 Siman, 2013, Evidence that the blood biomarker SNTF predicts brain imaging changes and persistent cognitive dysfunction in mild TBI patients, Front Neurol, 4, 190, 10.3389/fneur.2013.00190 Siman, 2015, Serum SNTF increases in concussed professional ice hockey players and relates to the severity of post-concussion symptoms, J Neurotrauma, 32, 1294, 10.1089/neu.2014.3698 Stein, 2014, Chronic traumatic encephalopathy: a spectrum of neuropathological changes following repetitive brain trauma in athletes and military personnel, Alzheimers Res Ther, 6, 4, 10.1186/alzrt234 Stein, 2015, Beta-amyloid deposition in chronic traumatic encephalopathy, Acta Neuropathol, 130, 21, 10.1007/s00401-015-1435-y Stern, 2013, Clinical presentation of chronic traumatic encephalopathy, Neurology, 81, 1122, 10.1212/WNL.0b013e3182a55f7f Stern, 2016, Preliminary study of plasma exosomal tau as a potential biomarker for chronic traumatic encephalopathy, J Alzheimers Dis, 51, 1099, 10.3233/JAD-151028 Sundman, 2015, Neuroimaging assessment of early and late neurobiological sequelae of traumatic brain injury: implications for CTE, Front Neurosci, 9, 334, 10.3389/fnins.2015.00334 Todd, 2007, Ultrasensitive flow-based immunoassays using single-molecule counting, Clin Chem, 53, 1990, 10.1373/clinchem.2007.091181 Trojanowski, 1989, Distribution of tau proteins in the normal human central and peripheral nervous system, J Histochem Cytochem, 37, 209, 10.1177/37.2.2492045 Uhlen, 2015, Proteomics. Tissue-based map of the human proteome, Science, 347, 1260419, 10.1126/science.1260419 Unden, 2013, Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based update, BMC Med, 11, 50, 10.1186/1741-7015-11-50 Williams, 2010, Mild traumatic brain injury and postconcussion syndrome: a neuropsychological perspective, J Neurol Neurosurg Psychiatry, 81, 1116, 10.1136/jnnp.2008.171298 Yoshimura, 2008, Stability of pro-gastrin-releasing peptide in serum versus plasma, Tumour Biol, 29, 224, 10.1159/000152940 Zetterberg, 2016, Fluid biomarkers for mild traumatic brain injury and related conditions, Nat Rev Neurol, 12, 563, 10.1038/nrneurol.2016.127 Zetterberg, 2006, Neurochemical aftermath of amateur boxing, Arch Neurol, 63, 1277, 10.1001/archneur.63.9.1277 Zetterberg, 2013, Biomarkers of mild traumatic brain injury in cerebrospinal fluid and blood, Nat Rev Neurol, 9, 201, 10.1038/nrneurol.2013.9 Zetterberg, 2013, Plasma tau levels in Alzheimer's disease, Alzheimers Res Ther, 5, 9, 10.1186/alzrt163