Chronic effects of inflammation on tauopathies

Forrest, 2018, Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies, Brain, 141, 521, 10.1093/brain/awx328 Bennett, 2017, Enhanced tau aggregation in the presence of amyloid β, Am J Pathol, 187, 1601, 10.1016/j.ajpath.2017.03.011 Canet, 2022, Seizure activity triggers tau hyperphosphorylation and amyloidogenic pathways, Epilepsia, 63, 919, 10.1111/epi.17186 Edwards, 2020, Traumatic brain injury induces tau aggregation and spreading, J Neurotrauma, 37, 80, 10.1089/neu.2018.6348 Garg, 2019, Subacute sclerosing panencephalitis, Rev Med Virol, 29, 10.1002/rmv.2058 Gelpi, 2016, Neuropathological criteria of anti-IgLON5-related tauopathy, Acta Neuropathol, 132, 531, 10.1007/s00401-016-1591-8 Heneka, 2015, Neuroinflammation in Alzheimer's disease, Lancet Neurol, 14, 388, 10.1016/S1474-4422(15)70016-5 Ransohoff, 2012, Innate immunity in the central nervous system, J Clin Invest, 122, 1164, 10.1172/JCI58644 Paolicelli, 2022, Microglia states and nomenclature: a field at its crossroads, Neuron, 110, 3458, 10.1016/j.neuron.2022.10.020 Fulop, 2021, Immunology of aging: the birth of inflammaging, Clin Rev Allergy Immunol, 10.1007/s12016-021-08899-6 Bettcher, 2021, Peripheral and central immune system crosstalk in Alzheimer disease—a research prospectus, Nat Rev Neurol, 17, 689, 10.1038/s41582-021-00549-x Ising, 2019, NLRP3 inflammasome activation drives tau pathology, Nature, 575, 669, 10.1038/s41586-019-1769-z Moonen, 2023, Pyroptosis in Alzheimer's disease: cell type-specific activation in microglia, astrocytes and neurons, Acta Neuropathol, 145, 175, 10.1007/s00401-022-02528-y Decout, 2021, The cGAS-STING pathway as a therapeutic target in inflammatory diseases, Nat Rev Immunol, 21, 548, 10.1038/s41577-021-00524-z Jin, 2021, Tau activates microglia via the PQBP1-cGAS-STING pathway to promote brain inflammation, Nat Commun, 12, 10.1038/s41467-021-26851-2 Schett, 2018, Resolution of chronic inflammatory disease: universal and tissue-specific concepts, Nat Commun, 9, 10.1038/s41467-018-05800-6 Jonsson, 2013, Variant of TREM2 associated with the risk of Alzheimer's disease, N Engl J Med, 368, 107, 10.1056/NEJMoa1211103 Steinberg, 2015, Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease, Nat Genet, 47, 445, 10.1038/ng.3246 Jansen, 2019, Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk, Nat Genet, 51, 404, 10.1038/s41588-018-0311-9 Bellenguez, 2022, New insights into the genetic etiology of Alzheimer's disease and related dementias, Nat Genet, 54, 412, 10.1038/s41588-022-01024-z Jain, 2023, Chronic TREM2 activation exacerbates Aβ-associated tau seeding and spreading, J Exp Med, 220, 10.1084/jem.20220654 Shi, 2017, ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy, Nature, 549, 523, 10.1038/nature24016 Lanfranco, 2021, Expression and secretion of apoE isoforms in astrocytes and microglia during inflammation, Glia, 69, 1478, 10.1002/glia.23974 Sepulveda-Falla, 2022, Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia, Acta Neuropathol, 144, 589, 10.1007/s00401-022-02467-8 Blanchard, 2022, APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes, Nature, 611, 769, 10.1038/s41586-022-05439-w McKee, 2020, The neuropathology of chronic traumatic encephalopathy: the status of the literature, Semin Neurol, 40, 359, 10.1055/s-0040-1713632 Qi, 2023, Identical tau filaments in subacute sclerosing panencephalitis and chronic traumatic encephalopathy, bioRxiv Pollanen, 2018, Nodding syndrome in Uganda is a tauopathy, Acta Neuropathol, 136, 691, 10.1007/s00401-018-1909-9 Sabater, 2014, A novel non-rapid-eye movement and rapid-eye-movement parasomnia with sleep breathing disorder associated with antibodies to IgLON5: a case series, characterisation of the antigen, and post-mortem study, Lancet Neurol, 13, 575, 10.1016/S1474-4422(14)70051-1 Falcon, 2019, Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules, Nature, 568, 420, 10.1038/s41586-019-1026-5 Tagge, 2018, Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model, Brain, 141, 422, 10.1093/brain/awx350 Ramos-Cejudo, 2018, Traumatic brain injury and Alzheimer's disease: the cerebrovascular link, EBioMedicine, 28, 21, 10.1016/j.ebiom.2018.01.021 Cherry, 2016, Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy, Acta Neuropathol Commun, 4, 112, 10.1186/s40478-016-0382-8 Chancellor, 2021, Altered oligodendroglia and astroglia in chronic traumatic encephalopathy, Acta Neuropathol, 142, 295, 10.1007/s00401-021-02322-2 Atherton, 2022, Association of APOE genotypes and chronic traumatic encephalopathy, JAMA Neurol, 79, 787, 10.1001/jamaneurol.2022.1634 Giarratana, 2020, APOE4 genetic polymorphism results in impaired recovery in a repeated mild traumatic brain injury model and treatment with Bryostatin-1 improves outcomes, Sci Rep, 10, 10.1038/s41598-020-76849-x Johnson, 2020, The pathogenesis of nodding syndrome, Annu Rev Pathol, 15, 395, 10.1146/annurev-pathmechdis-012419-032748 Idro, 2018, The natural history of nodding syndrome, Epileptic Disord, 20, 508, 10.1684/epd.2018.1012 Mazumder, 2023, Comparison of structural changes in nodding syndrome and other epilepsies associated with Onchocerca volvulus, Neurol Neuroimmunol Neuroinflamm, 10, 10.1212/NXI.0000000000200074 Pollanen, 2022, The spectrum of disease and tau pathology of nodding syndrome in Uganda, Brain Armangue, 2018, Frequency, symptoms, risk factors, and outcomes of autoimmune encephalitis after herpes simplex encephalitis: a prospective observational study and retrospective analysis, Lancet Neurol, 17, 760, 10.1016/S1474-4422(18)30244-8 Johnson, 2017, Nodding syndrome may be an autoimmune reaction to the parasitic worm Onchocerca volvulus, Sci Transl Med, 9, 10.1126/scitranslmed.aaf6953 Hotterbeekx, 2019, Neuroinflammation and not tauopathy is a predominant pathological signature of nodding syndrome, J Neuropathol Exp Neurol, 78, 1049, 10.1093/jnen/nlz090 Ogwang, 2021, Systemic and cerebrospinal fluid immune and complement activation in Ugandan children and adolescents with long-standing nodding syndrome: a case-control study, Epilepsia Open, 6, 297, 10.1002/epi4.12463 Vezzani, 2019, Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy, Nat Rev Neurol, 15, 459, 10.1038/s41582-019-0217-x Soldatos, 2022, Genomic analysis, immunomodulation and deep phenotyping of patients with nodding syndrome, Brain Miyahara, 2022, Independent distribution between tauopathy secondary to subacute sclerotic panencephalitis and measles virus: an immunohistochemical analysis in autopsy cases including cases treated with aggressive antiviral therapies, Brain Pathol, 32, 10.1111/bpa.13069 Watanabe, 2015, Measles virus mutants possessing the fusion protein with enhanced fusion activity spread effectively in neuronal cells, but not in other cells, without causing strong cytopathology, J Virol, 89, 2710, 10.1128/JVI.03346-14 Liu, 2021, Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions, Nat Commun, 12 Watanabe, 2019, New insights into measles virus brain infections, Trends Microbiol, 27, 164, 10.1016/j.tim.2018.08.010 Wang, 2022, Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy, Nat Commun, 13 Kocaaga, 2022, Association of NOD1 and NOD2 polymorphisms with susceptibility to subacute sclerosing panencephalitis, J Child Neurol DeTure, 2019, The neuropathological diagnosis of Alzheimer's disease, Mol Neurodegener, 14, 32, 10.1186/s13024-019-0333-5 Johnson, 2021, Suspecting dementia: canaries, chameleons and zebras, Pract Neurol, 10.1136/practneurol-2021-003019 Livingston, 2020, Dementia prevention, intervention, and care: 2020 report of the Lancet Commission, Lancet, 396, 413, 10.1016/S0140-6736(20)30367-6 Nianogo, 2022, Risk factors associated with Alzheimer disease and related dementias by sex and race and ethnicity in the US, JAMA Neurol, 79, 584, 10.1001/jamaneurol.2022.0976 Hata, 2023, Past history of obesity triggers persistent epigenetic changes in innate immunity and exacerbates neuroinflammation, Science, 379, 45, 10.1126/science.abj8894 Sweeney, 2019, Vascular dysfunction—the disregarded partner of Alzheimer's disease, Alzheimers Dement, 15, 158, 10.1016/j.jalz.2018.07.222 Matsuyama, 2020, Chronic cerebral hypoperfusion activates AIM2 and NLRP3 inflammasome, Brain Res, 1736, 10.1016/j.brainres.2020.146779 Montagne, 2020, APOE4 leads to blood–brain barrier dysfunction predicting cognitive decline, Nature, 581, 71, 10.1038/s41586-020-2247-3 Levine, 2023, Virus exposure and neurodegenerative disease risk across national biobanks, Neuron, 10.1016/j.neuron.2022.12.029 Dominy, 2019, Porphyromonas gingivalis in Alzheimer's disease brains: evidence for disease causation and treatment with small-molecule inhibitors, Sci Adv, 5, 10.1126/sciadv.aau3333 Seo, 2023, ApoE isoform- and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy, Science, 379, 10.1126/science.add1236 Ball, 1982, “Limbic predilection in Alzheimer dementia: is reactivated herpesvirus involved?”, Can J Neurol Sci, 9, 303, 10.1017/S0317167100044115 Tiwari, 2006, Role for 3-O-sulfated heparan sulfate as the receptor for herpes simplex virus type 1 entry into primary human corneal fibroblasts, J Virol, 80, 8970, 10.1128/JVI.00296-06 Witoelar, 2018, Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci, Sci Rep, 8, 10.1038/s41598-018-36429-6 Zhao, 2017, Glycan Determinants of Heparin-Tau Interaction, Biophys J, 112, 921, 10.1016/j.bpj.2017.01.024 Stopschinski, 2018, Specific glycosaminoglycan chain length and sulfation patterns are required for cell uptake of tau versus α-synuclein and β-amyloid aggregates, J Biol Chem, 293, 10826, 10.1074/jbc.RA117.000378 Zhao, 2020, 3-O-sulfation of heparan sulfate enhances tau interaction and cellular uptake, Angew Chem Int Ed Engl, 59, 1818, 10.1002/anie.201913029 Tzeng, 2018, Anti-herpetic medications and reduced risk of dementia in patients with herpes simplex virus infections—a nationwide, population-based cohort study in Taiwan, Neurotherapeutics, 15, 417, 10.1007/s13311-018-0611-x Bjornevik, 2022, Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis, Science, 375, 296, 10.1126/science.abj8222 Cairns, 2020, A 3D human brain-like tissue model of herpes-induced Alzheimer's disease, Sci Adv, 6, 10.1126/sciadv.aay8828 Walker, 2019, Systemic inflammation during midlife and cognitive change over 20 years: the ARIC Study, Neurology, 92, e1256 Zhou, 2020, Tumor necrosis factor (TNF) blocking agents are associated with lower risk for Alzheimer's disease in patients with rheumatoid arthritis and psoriasis, PLoS One, 15 Fong, 2022, The inter-relationship between delirium and dementia: the importance of delirium prevention, Nat Rev Neurol, 18, 579, 10.1038/s41582-022-00698-7 Pascoal, 2021, Microglial activation and tau propagate jointly across Braak stages, Nat Med, 27, 1592, 10.1038/s41591-021-01456-w Nutma, 2022, Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases, bioRxiv Tai, 2016, Hyperphosphorylated tau in patients with refractory epilepsy correlates with cognitive decline: a study of temporal lobe resections, Brain, 139, 2441, 10.1093/brain/aww187 Busch, 2020, Verbal memory dysfunction is associated with alterations in brain transcriptome in dominant temporal lobe epilepsy, Epilepsia, 61, 2203, 10.1111/epi.16673 Pooler, 2013, Physiological release of endogenous tau is stimulated by neuronal activity, EMBO Rep, 14, 389, 10.1038/embor.2013.15 Wu, 2016, Neuronal activity enhances tau propagation and tau pathology in vivo, Nat Neurosci, 19, 1085, 10.1038/nn.4328 Lopez, 2022, Event-based modeling in temporal lobe epilepsy demonstrates progressive atrophy from cross-sectional data, Epilepsia, 63, 2081, 10.1111/epi.17316 Whelan, 2018, Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study, Brain, 141, 391, 10.1093/brain/awx341 Altmann, 2022, A systems-level analysis highlights microglial activation as a modifying factor in common epilepsies, Neuropathol Appl Neurobiol, 48, 10.1111/nan.12758 Terrone, 2019, Inflammation and reactive oxygen species in status epilepticus: Biomarkers and implications for therapy, Epilepsy Behav, 101, 10.1016/j.yebeh.2019.04.028 Dilena, 2019, Therapeutic effect of Anakinra in the relapsing chronic phase of febrile infection-related epilepsy syndrome, Epilepsia Open, 4, 344, 10.1002/epi4.12317 Zhang, 2022, Role of HMGB1/TLR4 and IL-1β/IL-1R1 signaling pathways in epilepsy, Front Neurol, 13 Jellinger, 2009, Absence of alpha-synuclein pathology in postencephalitic parkinsonism, Acta Neuropathol, 118, 371, 10.1007/s00401-009-0537-9 Mulroy, 2020, Some new and unexpected tauopathies in movement disorders, Mov Disord Clin Pract (Hoboken), 7, 616, 10.1002/mdc3.12995 McCall, 2001, Influenza RNA not detected in archival brain tissues from acute encephalitis lethargica cases or in postencephalitic Parkinson cases, J Neuropathol Exp Neurol, 60, 696, 10.1093/jnen/60.7.696 Ahmed, 2015, Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2, Sci Transl Med, 7, 10.1126/scitranslmed.aab2354 Dale, 2004, Encephalitis lethargica syndrome: 20 new cases and evidence of basal ganglia autoimmunity, Brain, 127, 21, 10.1093/brain/awh008 Gaig, 2019, Neurological profiles beyond the sleep disorder in patients with anti-IgLON5 disease, Curr Opin Neurol, 32, 493, 10.1097/WCO.0000000000000677 Grüter, 2022, Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease, Brain, 146, 600, 10.1093/brain/awac090 Dalakas, 2022, IgG4-mediated neurologic autoimmunities: understanding the pathogenicity of IgG4, ineffectiveness of IVIg, and long-lasting benefits of anti-B cell therapies, Neurol Neuroimmunol Neuroinflamm, 9, 10.1212/NXI.0000000000001116 Strippel, 2022, Increased intrathecal B and plasma cells in patients with anti-IgLON5 disease: a case series, Neurol Neuroimmunol Neuroinflamm, 9, 10.1212/NXI.0000000000001137 Gaig, 2017, Clinical manifestations of the anti-IgLON5 disease, Neurology, 88, 1736, 10.1212/WNL.0000000000003887 Gaig, 2019, HLA and microtubule-associated protein tau H1 haplotype associations in anti-IgLON5 disease, Neurol Neuroimmunol Neuroinflamm, 6, e605, 10.1212/NXI.0000000000000605 Landa, 2020, Effects of IgLON5 antibodies on neuronal cytoskeleton: a link between autoimmunity and neurodegeneration, Ann Neurol, 88, 1023, 10.1002/ana.25857 Ryding, 2021, Neurodegeneration induced by anti-IgLON5 antibodies studied in induced pluripotent stem cell-derived human neurons, Cells, 10, 837, 10.3390/cells10040837 Boyd, 2022, Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases, J Neuroinflammation, 19, 223, 10.1186/s12974-022-02584-x Gate, 2021, CD4+ T cells contribute to neurodegeneration in Lewy body dementia, Science, 374, 868, 10.1126/science.abf7266 Chia, 2021, Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture, Nat Genet, 53, 294, 10.1038/s41588-021-00785-3 Beckman, 2022, SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19, Cell Rep, 41, 10.1016/j.celrep.2022.111573 Meisl, 2021, In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease, Sci Adv, 7, 10.1126/sciadv.abh1448