Chromosome Complements of Isodon (Family: Lamiaceae–Subfamily: Nepetoideae): Trends in Karyotype Evolution

Sandhya Vincent Neelamkavil1, John E. Thoppil1
1Cell and Molecular Biology Division, Department of Botany, University of Calicut, Calicut, India

Tóm tắt

The use of Isodon in folk medicines has a long tradition. The tetracyclic compound ent-kaurane diterpenoids present in the genus have varied biological activities including antibacterial, anti-inflammatory and antitumor activity and makes it a good candidate in drug research. Being a cosmopolitan and important genus of the family Lamiaceae with considerable taxonomic dispute, a review on chromosome complements and its evolution is of great significance. The prevalence of confusion regarding the members of the genus makes it obligatory to include the synonymised members also. Hence, the review is made inclusive of Rabdosia, Isodon and members of Plectranthus which have now been included under the genus Isodon. The chromosome counts of all the reported species of Isodon have been examined and the haploid chromosome number was found to be n = 12. Except for the two species Isodon lophanthoides and Isodon ramosissimus for which the chromosome counts were reported as 2n = 36 and 2n = 42 respectively, all other species had 2n = 24 as its diploid count. The secondary basic chromosome number of x2 = 12 prevalent in majority of the taxa might have evolved from the primary base number x1 = 6 via protoautoploidy.

Tài liệu tham khảo

Harley RM, Atkins S, Budantsev AL et al (2004) Labiatae. In: Kadereit JW (ed) The families and genera of vascular plants, VI (Lamiales). Springer, Berlin, pp 167–275 Yu XQ, Maki M, Drew BT et al (2014) Phylogeny and historical biogeography of Isodon (Lamiaceae): rapid radiation in south-west China and Miocene overland dispersal into Africa. Mol Phylogenet Evol 77:183–194 Sun HD, Xu YL, Jiang B (2001) Diterpenoids from Isodon species. Science Press, Beijing Zou Q, Du J, Zhang H et al (2013) Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma. J Transl Med 11:200–211 Liao Y, Bai H, Li Z et al (2014) Longikaurin A, a natural ent-kaurane, induces G2/M phase arrest via downregulation of Skp2 and apoptosis induction through ROS/JNK/c-Jun pathway in hepatocellular carcinoma cells. Cell Death Dis 5:e1137. doi:10.1038/cddis.2014.66 Waldia S, Kaushik N, Verma AK et al (2013) Antibacterial and cytotoxic activities of diterpenoids isolated from Indian Plectranthus coesta. Rec Nat Prod 7:355–358 Ren H, Xu Q, Luo Y et al (2015) Two new ent-kaurane diterpenoids from Wedelia trilobata (L.) Hitchc. Phytochem Lett 11:260–263 Wu H, Wang W, Du X et al (2015) Six new cytotoxic and anti-inflammatory 11, 20-epoxy-ent kaurane diterpenoids from Isodon wikstroemioides. Chin J Nat Med 13:383–389 Liu G, Ding L, Yang Y, Yang H, Yang Q, Wang H (2006) Anti-oxidative action of ent-kaurene diterpenoids. Res Chem Intermed 32:787–794 Yang J, Du X, He F et al (2013) Bioactive abietane and ent-kaurane diterpenoids from Isodon tenuifolius. J Nat Prod 76:256–264 Jiang H, Wang W, Zhou M et al (2014) 6,7-seco-ent-Kaurane diterpenoids from Isodon sculponeatus and their bioactivity. Chin Chem Lett 25:541–544 Wu H, Zhan R, Wang W et al (2014) Cytotoxic ent-kaurane diterpenoids from Isodon wikstroemioides. J Nat Prod 77:931–941 Liu X, Yang J, Wang W et al (2015) Diterpene alkaloids with an aza-ent-kaurane skeleton from Isodon rubescens. J Nat Prod 78:196–201 Guerra M (2008) Chromosome numbers in plant cytotaxonomy: concepts and implications. Cytogenet Genome Res 120:339–350 Anil SR, Suhara Beevy S, Siril EA (2013) Karyosystematic studies in Amorphophallus Blume ex Decne. J Root Crops 39:39–50 Guerra M (2012) Cytotaxonomy: the end of childhood. Plant Biosyst 146:703–710 Codd LE (1968) Notes on the genus Isodon (Benth.) Kudo (Labiatae). Taxon 17:239 Li HW (1988) Taxonomic review of Isodon (Labiatae). J Arnold Arbor 69:289–400 Zhong JS, Li J, Li L, Conran JG, Li HW (2010) Phylogeny of Isodon (Schrad. ex Benth.) Spach (Lamiaceae) and related genera inferred from nuclear ribosomal ITS, trnL-trnF region, and rps16 intron sequences and morphology. Syst Bot 35:207–219 Heslop-Harrison JS, Schwarzacher T (2011) Organisation of the plant genome in chromosomes. Plant J 66:18–33 Levin DA, Wilson AC (1976) Rates of evolution in seed plants: net increase in diversity of chromosome numbers and species numbers through time. Proc Natl Acad Sci USA 73:2086–2090 Goldblatt P (2007) The index to plant chromosome numbers—past and future. Taxon 56:984–986 Mehra PN, Bawa KS (1972) Cytogenetical evolution of hardwoods. Nucleus 15:64–83 Levin DA (2002) The role of chromosomal change in plant evolution. Oxford University Press, United Kingdom Wakabayashi M (1973) A note on the genus Mitella of Japan. Acta Phytotax Geobot 25:136–153 Sokolovskaya AP, Probatova NS, Rudyka EG (1986) A contribution to the study of chromosome numbers and geographical distribution of some species of the family Lamiaceae in the Soviet Far East. Bot Zhurn SSSR 71:195–200 Khatoon S, Ali SI (1993) Chromosome atlas of the angiosperms of Pakistan. Department of Botany, University of Karachi, BCC and T Press, Karachi Shatalova SA (2000) Chromosome numbers in vascular plants of the Primorsky territory. Bot Zhurn (Moscow & Leningrad) 85:152–156 Probatova NS, Sokolovskaya AP, Rudyka EG, Shatalova SA (2000) Chromosome numbers in some plant species from the Razdolnaya (Suifun) river basin (Primorsky Territory). Bot Zhurn (Moscow & Leningrad) 85:102–107 Suzuka O (1950) Chromosome numbers in pharmaceutical plants I. Seiken Ziho, Rept Kihara Inst Biol Res 4:57–58 de Wet JMJ (1958) Chromosome numbers in Plectranthus and related genera. S Afr J Sci 54:153–156 Paton AJ, Springate D, Suddee S et al (2004) Phylogeny and evolution of basils and allies (Ocimeae, Labiatae) based on three plastid DNA regions. Mol Phylogenet Evol 31:277–299 Mehra PN, Gill LS (1972) Cytology of west Himalayan Labiatae: tribe Ocimoideae. Cytologia 37:53–57 Bir SS, Saggoo MIS (1981) Cytopalynology of certain Acanthaceae and Labiatae. J Palynol 17:93–102 Bir SS, Saggoo MIS (1984) Cytological studies on the family Labiatae from Garhwal Himalayas. In: Paliwal GS (ed) The vegetational wealth of the Himalayas. Puja Publishers, New Delhi, pp 471–482 Saggoo MIS (1983) Cytomorphological studies on plants of economic importance of Bicarpellatae from India. Ph.D. Thesis, Punjab University, Patiala Gill LS (1984) The incidence of polyploidy in the west-Himalayan Labiatae. Rev Cytol Biol Vég Bot 7:5–16 Saggoo MIS, Bir SS (1986) Meiotic studies on some east Himalayan members of family Labiatae. J Indian Bot Soc 65:304–309 Krishnappa DG, Basavaraj I (1982) IOPB chromosome number reports LXXV. Taxon 31:361–362 Vij SP, Kashyap SK (1975) IOPB chromosome number reports XLVIII. Taxon 24:367–372 Vij SP, Kashyap SK (1976) Cytological studies in some north Indian Labiatae. Cytologia 41:713–719 Bir SS, Saggoo MIS (1980) Chromosome number reports LXIX. Taxon 29:703–730 Cherian M, Kuriachan PI (1981) Chromosome number reports LXXII. Taxon 30:707–708 Saggoo MIS, Bir SS (1982) IOPB chromosome number reports LXXVI. Taxon 31:593–595 Saggoo MIS, Bir SS (1983) Cytopalynological studies on Indian members of Acanthaceae and Labiatae. J Palynol 19:243–277 Bir SS, Saggoo MIS (1985) Cytological studies on members of family Labiatae from Kodaikanal and adjoining areas (South India). Proc Indian Acad Sci (Plant Sci) 94:619–626 Thoppil JE, Jose J (1996) Relation between meiotic status and apomixis in Plectranthus L’Her. Cell Chromosome Res 19:46–48 Thoppil JE, Jose J (1996) Chromosome analysis as correlated with essential oil composition in two species of Plectranthus. Nucleus 39:144–147 Evans GM (1988) Genetic control of chromosome pairing in polyploids. In: Brandham PE (ed) Kew Chromosome Conference III. HMSO, London, pp 253–260 Morton JK (1993) Chromosome numbers and polyploidy in the flora of Cameroon Mountain. Opera Bot 121:159–172 Jin Z, Sha W (2004) The karyotype study on Isodon japonica var. glaucocalyx and Leonurus japonicus. Guangxi Sci 11:78–80 Yamashiro T, Suzuki K, Maki M (2005) Chromosome numbers of Isodon (Lamiaceae) in Japan. Acta Phytotax Geobot 56:241–246 Huang SS (2011) Studies on chromosome number of four original species of Chinese medicine Xihuangcao. J Trop Subtrop Bot 19:374–376 Xiang C, Chen Y, Tsuneo F, Peng H (2014) Cytology of thirteen taxa in the genus Isodon (Lamiaceae: Nepetoideae) from China. Plant Divers Resour 36:561–568 Suddee S, Paton AJ, Parnell JAN (2004) A taxonomic revision of tribe Ocimeae Dumort. (Lamiaceae) in continental South East Asia I. Introduction, Hyptidinae & Hanceolinae. Kew Bull 59:337–378 Ryding O (1993) A reconsideration of the genus Rabdosiella (Lamiaceae, Nepetoideae, Ocimeae). Plant Syst Evol 185:91–97 Paton A, Ryding O (1998) Hanceola, Siphocranion and Isodon and their position in the Ocimeae (Labiatae). Kew Bull 53:723–731 Harley RM, Paton AJ, Ryding O (2003) New synonymy and taxonomic changes in the Labiatae. Kew Bull 58:485–489 Darlington CD, Wylie AP (1955) Chromosome atlas of flowering plants. Allen and Unwin Ltd, London Lysak MA, Berr A, Pecinka A, Schmidt R, McBreen K, Schubert I (2006) Mechanisms of chromosome number reduction in Arabidopsis thaliana and related Brassicaceae species. Proc Natl Acad Sci USA 103:5224–5229