Cholesterol-enriched membrane micro-domain deficiency induces doxorubicin resistance via promoting autophagy in breast cancer

Molecular Therapy - Oncolytics - Tập 23 - Trang 311-329 - 2021
Yin Shi1,2, Zu Ye2,3, Guang Lu2, Naidi Yang2,4, Jianbin Zhang2, Liming Wang2,5, Jianzhou Cui2, Miguel A. del Pozo6, Yihua Wu7, Dajing Xia7, Han-Ming Shen2,8
1Department of Immunology, Zhejiang University School of Medicine, Hangzhou 310058, China
2Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore 119077, Singapore
3Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston 77030, USA
4Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University, Nanjing, Jiangsu Province 211800, China
5School of Biomedical Science, Hunan University, Changsha, Hunan, China
6Integrin Signaling Laboratory, Vascular Biology and Inflammation Department, Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain
7Department of Toxicology of School of Public Health, and Department of Gynecologic Oncology of Women's Hospital, Zhejiang University School of Medicine, Hangzhou 310058, China
8Faculty of Health Sciences, University of Macau, Macau SAR 999078, China

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