Cholesterol-binding cytolytic protein toxins

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Gilbert, 1999, Two structural transitions in membrane pore formation by pneumolysin, the pore-forming toxin of Streptococcus pneumoniae, Cell, 97, 647, 10.1016/S0092-8674(00)80775-8

Guzman, 1996, Apoptosis of mouse dentritic cells triggered by listeriolysin, the major virulence determinant of Listeria monocytogenes, Mol. Microbiol., 20, 119, 10.1111/j.1365-2958.1996.tb02494.x

Haas, 1992, Listeriolysin genes: complete nucleotide sequence of ilo ivanolysin from Listeria ivanovii and of listeriolysin from Listeria seeligeri, Biochim. Biophys. Acta, 1130, 81, 10.1016/0167-4781(92)90466-D

Hackett, 1992, Streptococcal toxic shock syndrome: synthesis of tumor necrosis factor and IL-1 by monocytes stimulated with pyrogenic exotoxin A and streptolysin O, J. Infect. Dis., 165, 879, 10.1093/infdis/165.5.879

Hill, 1994, Amino acids in pneumolysin important for hemolytic activity identified by random mutagenesis, Infect. Immun., 62, 757, 10.1128/IAI.62.2.757-758.1994

Houldsworth, 1994, Pneumolysin stimulates production of tumor necrosis factor alpha and interleukin-1\β by human mononuclear phagocytes, Infect. Immun., 62, 1501, 10.1128/IAI.62.4.1501-1503.1994

Jacobs, 1998, Listeriolysin O: Cholesterol inhibits cytolysis but not binding to cellular membranes, Mol. Microbiol., 28, 1081, 10.1046/j.1365-2958.1998.00858.x

Johnson, 1980, Binding of cholesterol by sulfhydryl-activated cytolysins, Infect. Immun., 27, 97, 10.1128/IAI.27.1.97-101.1980

Kayal, 1999, Listeriolysin O-dependent activation of endothelial cells during infection with Listeria monocytogenes activation of NK-χB and upregulation of adhesion molecules, Mol. Microbiol., 31, 1709, 10.1046/j.1365-2958.1999.01305.x

Kehoe, 1987, Nucleotide sequence of the streptolysin O (SLO) gene: structural homologies between SLO and other membrane-damaging, thiol-activated toxins, Infect. Immun., 55, 3228, 10.1128/IAI.55.12.3228-3232.1987

König, 1994, Activation of human effector cells by different bacterial toxins (leukocidin, alveolysin, erythrogenic toxin A): generation of interleukin-8, Infect. Immun., 62, 4831, 10.1128/IAI.62.11.4831-4837.1994

Launay, 1984, Purified SH-activated toxins (streptolysin O, alveolysin): new tools for determination of platelet enzyme activities, Thromb. Res., 33, 189, 10.1016/0049-3848(84)90179-8

Mengaud, 1988, Expression in Escherichia coli and sequences of the listeriolysin O determinant of Listeria monocytogenes, Infect. Immun., 56, 766, 10.1128/IAI.56.4.766-772.1988

Michel, 1990, Attenuated mutants of the intracellular bacterium Listeria monocytogenes obtained by a single amino acid substitution in listeriolysin O, Mol. Microbiol., 4, 2167, 10.1111/j.1365-2958.1990.tb00578.x

Mitchell, 1991, Complement activation and antibody binding by pneumolysin via a region of the toxin homologous to a human acute-phase protein, Mol. Microbiol., 5, 1883, 10.1111/j.1365-2958.1991.tb00812.x

Mitchell, 1999, Pneumolysin: structure, function and role in disease, 386

Nishibori, 1996, Induction of cytokine gene expression by listeriolysin O and roles of macrophages and NK cells, Infect. Immun., 64, 3188, 10.1128/IAI.64.8.3188-3195.1996

Ohno-Iwashita, 1988, Protease-nicked θ-toxin of Clostridium perfringens a new membrane probe with no catalytic effects reveals two classes of cholesterol as toxin-binding sites on sheep erythrocytes, Eur. J. Biochem., 176, 95, 10.1111/j.1432-1033.1988.tb14255.x

Okumuru, 1994, Cloning and sequencing the streptolysin O genes of group C and group G streptococci, DNA Seq., 4, 325, 10.3109/10425179409020859

Paton, 1984, Activation of human complement by the pneumococcal toxin pneumolysin, Infect. Immun., 43, 1085, 10.1128/IAI.43.3.1085-1087.1984

Pinkney, 1989, The thiol-activated toxin streptolysin O does not require a thiol group for cytolytic activity, Infect. Immun., 57, 2553, 10.1128/IAI.57.8.2553-2558.1989

Prigent, 1976, Interaction of streptolysin O with sterols, Biochim. Biophys. Acta, 443, 288, 10.1016/0005-2736(76)90511-3

Rossjohn, 1997, Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form, Cell, 89, 685, 10.1016/S0092-8674(00)80251-2

Rossjohn, 1998, The molecular mechanisms of pneumolysin, a virulence factor from Streptococcus pneumoniae, J. Mol. Biol., 284, 449, 10.1006/jmbi.1998.2167

Rossjohn, 1999, Perfringolysin O, 496

Saunders, 1989, Pneumolysin, the thiol-activated toxin of Streptococcus pneumoniae does not require a thiol group for in vivo activity, Infect. Immun., 57, 2547, 10.1128/IAI.57.8.2547-2552.1989

Segers, 1998, Characterization of the gene encoding suilysin from Streptococcus suis and expression in field strains, FEMS Microbiol. Lett., 167, 255, 10.1111/j.1574-6968.1998.tb13236.x

Sekino-Suzuki, 1996, Contribution of individual tryptophan residues to the structure and activity of θ-toxin (perfringolysin O), a cholesterin-binding cytolysin, Eur. J. Biochem., 241, 941, 10.1111/j.1432-1033.1996.00941.x

Sekiya, 1998, Formation of ring-shaped structures on erythrocyte membranes after treatment with botulinolysin a thiol-activated hemolysin from Clostridium botulinum, Infect. Immun., 66, 2987, 10.1128/IAI.66.6.2987-2990.1998

Shanley, 1996, Streptococcal cysteine protease augments lung injury induced by products of group A streptococci, Infect. Immun., 64, 870, 10.1128/IAI.64.3.870-877.1996

Shepard, 1998, Identification of a membrane-spanning domain of the thiol-activated, pore-forming toxin Clostridium perfringens perfringolysin O: an α-helical to β-sheet transition identified by fluorescence spectroscopy, Biochemistry, 37, 14563, 10.1021/bi981452f

Sibelius, 1996, Listeriolysin is a potent inducer of phosphatidylinositol response and lipid mediator generation in human endothelial cells, Infect. Immun., 64, 674, 10.1128/IAI.64.2.674-676.1996

Smyth, 1978, Thiol-activated (oxygen-labile) cytolysin, 129

Thelestam, 1980, Interaction of streptolysin O from Streptococcus pyogenes and theta toxin from Clostridium perfringens with human fibroblasts, Infect. Immun., 29, 863, 10.1128/iai.29.3.863-872.1980

Thelestam, 1981, Membrane-damaging action of alveolysin from Bacillus alvei, Infect. Immun., 32, 1187, 10.1128/IAI.32.3.1187-1192.1981

Todd, 1934, A comparative serological study of streptolysins derived from human and from animal infections, with notes on pneumococcal haemolysin, tetanolysin and staphylococcus toxin, J. Pathol. Bacteriol., 39, 299, 10.1002/path.1700390207

Tweten, 1988, Cloning and expression in Escherichia coli of the perfringolysin O (theta toxin) gene from Clostridium perfringens and characterization of the gene product, Infect. Immun., 56, 3228, 10.1128/IAI.56.12.3228-3234.1988

Vazquez-Boland, 1989, Preliminary evidence that different domains are involved in cytolytic activity and receptor (cholesterol) binding in listeriolysin O, the Listeria monocytogenes thiol-activated toxin, FEMS Microbiol. Lett., 65, 95, 10.1111/j.1574-6968.1989.tb03603.x

Walker, 1987, Molecular cloning, characterization and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae, Infect. Immun., 55, 1184, 10.1128/IAI.55.5.1184-1189.1987

Watson, 1974, Sterol requirements for inhibition of streptolysin O activity, Biochem. J., 140, 95, 10.1042/bj1400095

Yutsudo, 1994, Amino acid sequence of cereolysin (derived from nucleotide sequence PID: g600252), Genbank Accession: D21270