Chikungunya Virus Infection: First Detection of Imported and Autochthonous Cases in Panama

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE - Tập 92 Số 3 - Trang 482-485 - 2015
Yamilka Díaz1,2,3,4,5,6, Ana Belén Araúz1,2,3,4,5,6, Ana Margarita Botello1,2,3,4,5,6, Sandra López‐Vergès1,2,3,4,5,6, Lizbeth Cerezo1,2,3,4,5,6, Jean‐Paul Carrera1,2,3,4,5,6, Blas Armién1,2,3,4,5,6, Lourdes Moreno1,2,3,4,5,6, Vassilis Zafiropulos1,2,3,4,5,6, Ilka Guerra1,2,3,4,5,6, Yamileth López1,2,3,4,5,6, Dimelza Araúz1,2,3,4,5,6, Vladimir Gonzalez1,2,3,4,5,6, Brechla Moreno1,2,3,4,5,6
1Columbus University, Panama City, Panama; National Department of Epidemiology,
2Department of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Justo Arosemena Avenue, 35th, Panama City 0816-02593, Panama.
3Departments of Research in Virology and Biotechnology and Emerging and Zoonotic Diseases, Gorgas Memorial Institute of Health Studies, Panama City, Panama; School of Medicine,
4Division of Infectious Diseases, Hospital Santo Tomas, Panama City, Panama;
5Ministry of Health, Panama City, Panama;
6Policentro de Parque Lefevre, Panama City, Panama; Centro de Salud de Rio Abajo, Panama City, Panama

Tóm tắt

Chikungunya virus (CHIKV) is a mosquito-borne pathogen that was only endemic in Africa and south Asia until 2005 and 2006, when the virus spread into the Indian Ocean islands, Europe, and Asia. Autochthonous CHIKV transmission in the Caribbean islands was reported in December of 2013. In Panama, two febrile cases were detected in May of 2014: one traveling from Haiti, and the other traveling from the Dominican Republic. After other imported cases were detected, the first autochthonous case was reported in August of the same year. We detected CHIKV viral RNA and isolated the virus from serum samples. The phylogenetic analysis of the two imported isolates and one autochthonous CHIKV isolate indicated that the viruses belong to the Asian lineage in the Caribbean clade and are related to viruses recently identified in Saint Martin island, British Virgin Islands, China, and the Philippines. Although the circulating CHIKV lineages in the Americas have not yet been described, our results suggest that the Asian lineage is circulating in most American countries reporting autochthonous infection.

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AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Tập 92 Số 3

482-485

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