Chick chorioallantoic membrane (CAM) assay for the evaluation of the antitumor and antimetastatic activity of platinum-based drugs in association with the impact on the amino acid metabolism

Manzoor, 2021, Biofabricated platinum nanoparticles: therapeutic evaluation as a potential nanodrug against breast cancer cells and drug-resistant bacteria, RSC Adv., 11, 24900, 10.1039/D1RA03133C Ullah, 2017, Bio-fabrication of catalytic platinum nanoparticles and their in vitro efficacy against lungs cancer cells line (A549), J. Photochem. Photobiol., B, 173, 368, 10.1016/j.jphotobiol.2017.06.018 Sahin, 2018, Cytotoxic effects of platinum nanoparticles obtained from pomegranate extract by the green synthesis method on the MCF-7 cell line, Colloids Surf. B Biointerfaces, 163, 119, 10.1016/j.colsurfb.2017.12.042 Abed, 2022, Platinum nanoparticles in biomedicine: preparation, anti-cancer activity, and drug delivery vehicles, Front. Pharmacol., 13, 10.3389/fphar.2022.797804 Jeyaraj, 2019, A comprehensive review on the synthesis, characterization, and biomedical application of platinum nanoparticles, Nanomaterials, 9 Nejdl, 2017, Platinum nanoparticles induce damage to DNA and inhibit DNA replication, PLoS One, 12, 10.1371/journal.pone.0180798 Baskaran, 2017, Cytotoxic potentials of biologically fabricated platinum nanoparticles from Streptomyces sp. on MCF-7 breast cancer cells, IET Nanobiotechnol., 11, 241, 10.1049/iet-nbt.2016.0040 Bendale, 2016, Biosynthesized platinum nanoparticles inhibit the proliferation of human lung-cancer cells in vitro and delay the growth of a human lung-tumor xenograft in vivo: -in vitro and in vivo anticancer activity of bio-Pt NPs, J. Pharmacopuncture, 19, 114, 10.3831/KPI.2016.19.012 Bendale, 2017, Evaluation of cytotoxic activity of platinum nanoparticles against normal and cancer cells and its anticancer potential through induction of apoptosis, Integr Med Res, 6, 141, 10.1016/j.imr.2017.01.006 Medhat, 2017, Evaluation of the antitumor activity of platinum nanoparticles in the treatment of hepatocellular carcinoma induced in rats, Tumour Biol, 39, 10.1177/1010428317717259 Kutwin, 2017, Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme, Arch. Med. Sci., 13, 1322, 10.5114/aoms.2016.58925 Akram, 2014, Citric acid cycle and role of its intermediates in metabolism, Cell Biochem. Biophys., 68, 475, 10.1007/s12013-013-9750-1 Lyssiotis, 2013, Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance, Cell Cycle, 12, 1987, 10.4161/cc.25307 Wang, 2017, ATP citrate lyase is increased in human breast cancer, depletion of which promotes apoptosis, Tumour Biol, 39 Liu, 2018, 20 Simpson, 2011, An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression, Breast Cancer Res. Treat., 133, 959, 10.1007/s10549-011-1871-x Yoo, 2020, Glutamine reliance in cell metabolism, Exp. Mol. Med., 52, 1496, 10.1038/s12276-020-00504-8 Anderson, 2018, The emerging role and targetability of the TCA cycle in cancer metabolism, Protein Cell, 9, 216, 10.1007/s13238-017-0451-1 Moffatt, 2002, Purine and pyrimidine nucleotide synthesis and metabolism, Arabidopsis Book, 1, 10.1199/tab.0018 Green, 2016, Branched-chain amino acid catabolism fuels adipocyte differentiation and lipogenesis, Nat. Chem. Biol., 12, 15, 10.1038/nchembio.1961 Broer, 2017, Amino acid homeostasis and signalling in mammalian cells and organisms, Biochem. J., 474, 1935, 10.1042/BCJ20160822 Bachhawat, 2018, The glutathione cycle: glutathione metabolism beyond the gamma-glutamyl cycle, IUBMB Life, 70, 585, 10.1002/iub.1756 Rupp, 2022, A face-to-face comparison of tumor chicken chorioallantoic membrane (TCAM) in ovo with murine models for early evaluation of cancer therapy and early drug toxicity, Cancers, 14, 10.3390/cancers14143548 Buhr, 2020, The chorioallantoic membrane assay in nanotoxicological research-an alternative for in vivo experimentation, Nanomaterials, 10, 10.3390/nano10122328 S. Intasa-ard, A. Birault, Nanoparticles characterization using the CAM assay, in: F. Tamanoi (Ed.) The Enzymes, Academic Press2019, pp. 129-160. Lokman, 2012, Chick chorioallantoic membrane (CAM) assay as an in vivo model to study the effect of newly identified molecules on ovarian cancer invasion and metastasis, Int. J. Mol. Sci., 13, 9959, 10.3390/ijms13089959 Ribatti, 2017, The chick embryo chorioallantoic membrane (CAM) assay, Reprod. Toxicol., 70, 97, 10.1016/j.reprotox.2016.11.004 Vargas, 2007, The chick embryo and its chorioallantoic membrane (CAM) for the in vivo evaluation of drug delivery systems, Adv. Drug Deliv. Rev., 59, 1162, 10.1016/j.addr.2007.04.019 Merlos Rodrigo, 2021, Extending the applicability of in ovo and ex ovo chicken chorioallantoic membrane assays to study cytostatic activity in neuroblastoma cells, Front. Oncol., 11, 10.3389/fonc.2021.707366 Buchtelova, 2017, Size-related cytotoxicological aspects of polyvinylpyrrolidone-capped platinum nanoparticles, Food Chem. Toxicol., 105, 337, 10.1016/j.fct.2017.04.043 Heger, 2015, 17beta-estradiol-containing liposomes as a novel delivery system for the antisense therapy of ER-positive breast cancer: an in vitro study on the MCF-7 cell line, Oncol. Rep., 33, 921, 10.3892/or.2014.3627 Pawlikowska, 2020, Exploitation of the chick embryo chorioallantoic membrane (CAM) as a platform for anti-metastatic drug testing, Sci. Rep., 10, 10.1038/s41598-020-73632-w Augustine, 2020, A novel in ovo model to study cancer metastasis using chicken embryos and GFP expressing cancer cells, Bosn. J. Basic Med. Sci., 20, 140 Aranda, 2012, Bleach gel: a simple agarose gel for analyzing RNA quality, Electrophoresis, 33, 366, 10.1002/elps.201100335 Pfaffl, 2004, Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper--Excel-based tool using pair-wise correlations, Biotechnol. Lett., 26, 509, 10.1023/B:BILE.0000019559.84305.47 Ye, 2016, Explicit detection of the mechanism of platinum nanoparticle shape control by polyvinylpyrrolidone, J. Phys. Chem. C, 120, 7532, 10.1021/acs.jpcc.5b10910 Safo, 2019, The role of polyvinylpyrrolidone (PVP) as a capping and structure-directing agent in the formation of Pt nanocubes, Nanoscale Adv., 1, 3095, 10.1039/C9NA00186G Mitrevska, 2022, Platinum-based drug-induced depletion of amino acids in the kidneys and liver, Front. Oncol., 12, 10.3389/fonc.2022.986045 Rodrigo, 2021, Metallothionein-3 promotes cisplatin chemoresistance remodelling in neuroblastoma, Sci. Rep., 11, 5496, 10.1038/s41598-021-84185-x Pedone, 2017, Platinum nanoparticles in nanobiomedicine, Chem. Soc. Rev., 46, 4951, 10.1039/C7CS00152E Kaneda, 2004, The use of PVP as a polymeric carrier to improve the plasma half-life of drugs, Biomaterials, 25, 3259, 10.1016/j.biomaterials.2003.10.003 Zhang, 2015, PEGylation of carbon nanotubes via mussel inspired chemistry: preparation, characterization and biocompatibility evaluation, Appl. Surf. Sci., 351, 425, 10.1016/j.apsusc.2015.05.160 Caracciolo, 2017, Biological identity of nanoparticles in vivo: clinical implications of the protein corona, Trends Biotechnol., 35, 257, 10.1016/j.tibtech.2016.08.011 Franco, 2020, The use of poly(N-vinyl pyrrolidone) in the delivery of drugs: a review, Polymers, 12 Yang, 2021, Resveratrol enhances inhibition effects of cisplatin on cell migration and invasion and tumor growth in breast cancer MDA-MB-231 cell models in vivo and in vitro, Molecules, 26 Skowron, 2017, Applying the chicken embryo chorioallantoic membrane assay to study treatment approaches in urothelial carcinoma, Urol. Oncol., 35, 544 e11, 10.1016/j.urolonc.2017.05.003 Sarogni, 2022, Chorioallantoic membrane tumor models highlight the effects of cisplatin compounds in oral carcinoma treatment, iScience, 25, 10.1016/j.isci.2022.103980 Iyer, 2006, Exploiting the enhanced permeability and retention effect for tumor targeting, Drug Discov. Today, 11, 812, 10.1016/j.drudis.2006.07.005 Vu, 2018, Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer, Sci. Rep., 8, 10.1038/s41598-018-25573-8 Mapanao, 2022 Wang, 2022, Platinum nanoparticles promote breast cancer cell metastasis by disrupting endothelial barrier and inducing intravasation and extravasation, Nano Res., 15, 7366, 10.1007/s12274-022-4404-5 Kim, 2016, Quantification of cancer cell extravasation in vivo, Nat. Protoc., 11, 937, 10.1038/nprot.2016.050 Galvez, 2019, Preclinical studies on metal based anticancer drugs as enabled by integrated metallomics and metabolomics, Metallomics, 11, 1716, 10.1039/c9mt00141g Kim, 2022, Using intracellular metabolic profiling to identify novel biomarkers of cisplatin-induced acute kidney injury in NRK-52E cells, J. Toxicol. Environ. Health, 85, 29, 10.1080/15287394.2021.1969305 Yoo, 2022, Amino acid metabolism in cancer drug resistance, Cells, 11 Gurunathan, 2020, Anisotropic platinum nanoparticle-induced cytotoxicity, apoptosis, inflammatory response, and transcriptomic and molecular pathways in human acute monocytic leukemia cells, Int. J. Mol. Sci., 21, 10.3390/ijms21020440 Gunda, 2020, Amino acids regulate cisplatin insensitivity in neuroblastoma, Cancers, 12, 10.3390/cancers12092576 Ryu, 2011, Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells, Toxicol. Appl. Pharmacol., 255, 94, 10.1016/j.taap.2011.06.004 Zhang, 2017, Branched-Chain amino acids as predictors for individual differences of cisplatin nephrotoxicity in rats: a pharmacometabonomics study, J. Proteome Res., 16, 1753, 10.1021/acs.jproteome.7b00014 Alonezi, 2018, Liquid chromatography mass spectrometry (LCMS) and phenotype microarray profiling of ovarian cancer cells after exposure to cisplatin, Current Metabolomics, 6, 112, 10.2174/2213235X05666170203120840 Alonezi, 2017, Metabolomic profiling of the synergistic effects of melittin in combination with cisplatin on ovarian cancer cells, Metabolites, 7, 10.3390/metabo7020014 Alonezi, 2016, Metabolomic profiling of the effects of melittin on cisplatin resistant and cisplatin sensitive ovarian cancer cells using mass spectrometry and biolog microarray technology, Metabolites, 6, 10.3390/metabo6040035 Tully, 2021, Biguanide drugs enhance cytotoxic effects of cisplatin by depleting aspartate and NAD+ in sensitive cancer cells, Cancer Biol. Ther., 22, 579, 10.1080/15384047.2021.1982599 Pan, 2022, Histidine-rich glycoprotein (HRGP): pleiotropic and paradoxical effects on macrophage, tumor microenvironment, angiogenesis, and other physiological and pathological processes, Genes Dis, 9, 381, 10.1016/j.gendis.2020.07.015 Zhang, 2016, Nanoparticle–liver interactions: cellular uptake and hepatobiliary elimination, J. Contr. Release, 240, 332, 10.1016/j.jconrel.2016.01.020 Dkhil, 2013, The potential role ofAzadirachta indicaTreatment on cisplatin-induced hepatotoxicity and oxidative stress in female rats, Oxid. Med. Cell. Longev., 1, 10.1155/2013/741817 Lieu, 2020, Amino acids in cancer, Exp. Mol. Med., 52, 15, 10.1038/s12276-020-0375-3 Korangath, 2015, Targeting glutamine metabolism in breast cancer with aminooxyacetate, Clin. Cancer Res., 21, 3263, 10.1158/1078-0432.CCR-14-1200 Aleshin, 2021, Interplay between thiamine and p53/p21 axes affects antiproliferative action of cisplatin in lung adenocarcinoma cells by changing metabolism of 2-oxoglutarate/glutamate, Front. Genet., 12, 10.3389/fgene.2021.658446 Tu, 2018, Altered energy metabolism and metabolic gene expression associated with increased metastatic capacity identified in MDA-MB-231 cell line variants, Journal of Cancer Metastasis and Treatment, 2018 Pinweha, 2019, MicroRNA-143-3p targets pyruvate carboxylase expression and controls proliferation and migration of MDA-MB-231cells, Arch. Biochem. Biophys., 677, 10.1016/j.abb.2019.108169 Puissegur, 2011, miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity, Cell Death Differ., 18, 465, 10.1038/cdd.2010.119 Fadejeva, 2017, MicroRNAs as regulators of cisplatin-resistance in non-small cell lung carcinomas, Oncotarget, 8, 115754, 10.18632/oncotarget.22975 Kharbangar, 2000, Effect of cisplatin on mitochondrial protein, glutathione, and succinate dehydrogenase in Dalton lymphoma-bearing mice, Cell Biology andToxicology, 16, 363, 10.1023/A:1007648427024 Kruspig, 2016, Targeting succinate:ubiquinone reductase potentiates the efficacy of anticancer therapy, Biochim. Biophys. Acta, 1863, 2065, 10.1016/j.bbamcr.2016.04.026 Ananieva, 2018, Branched-chain amino acid metabolism in cancer, Curr. Opin. Clin. Nutr. Metab. Care, 21, 64, 10.1097/MCO.0000000000000430 Luo, 2021, BCAT1 decreases the sensitivity of cancer cells to cisplatin by regulating mTOR-mediated autophagy via branched-chain amino acid metabolism, Cell Death Dis., 12, 169, 10.1038/s41419-021-03456-7 Zhang, 2017, Branched-chain amino acid transaminase 1 (BCAT1) promotes the growth of breast cancer cells through improving mTOR-mediated mitochondrial biogenesis and function, Biochem. Biophys. Res. Commun., 486, 224, 10.1016/j.bbrc.2017.02.101