Chemokines in the Inflammatory Bowel Diseases

MacDermott RP: Alterations in the mucosal immune system in ulcerative colitis and Crohn's disease. Med Clin North Am 78:1207–1231, 1994 MacDermott RP: The role of the mucosal immune system in inflammatory bowel disease. In Essentials of Mucosal Immunology, MF Kagnoff, H Kiyono, (eds). San Diego, Academic Press, 1996, pp 321–339 MacDermott RP: Etiology and pathogenesis of inflammatory bowel disease. Curr Opin Gastroenterol 13:302–306, 1997 MacDermott, RP: Immunology of inflammatory bowel disease. Curr Opin Gastroenterol 4:54–67, 1998 Saverymuttu SH, Peters AM, Lavender JP, Chadwick VS, Hodgson HJ: In vivo assessment of granulocyte migration to diseased bowel in Crohn's disease. Gut 26:378–383, 1985 Scholmerich J, Schmidt E, Schumichen C, Billmann P, Schmidt H, Gerok W: Scintigraphic assessment of bowel involvement and disease activity in Crohn's disease using technetium 99m hexamethyl propylene amine oxide as leukocyte label. Gastroenterology 95:1287–1293, 1988 Pullman WE, Sullivan PJ, Barrett PJ, Lising J, Booth JA, Doe WF: Assessment of inflammatory bowel disease activity by technetium 99m phagocyte scanning. Gastroenterology 95:989–996, 1988 Baggiolini M, Dewald B, Moser B: Interleukin-8 and related chemotactic cytokines—CXC and CC chemokines. Adv Immunol 55:97–179, 1994 Taub DD, Oppenheim JJ: Chemokines, inflammation and the immune system. Ther Immunol 1:229–246, 1994 Taub DD: Chemokine-leukocyte interactions. The voodoo that they do so well. Cytokine Growth Factor Rev 7:355–376, 1996 Adams DH, Lloyd AR: Chemokines: Leukocyte recruitment and activation cytokines. Lancet 349:490–495, 1997 Baggiolini M, Dewald B, Moser B: Human chemokines: An update. Annu Rev Immunol 15:675–705, 1997 Oppenheim JJ, Zachariae CO, Mukaida N, Matsushima K: Properties of the novel proinflammatory supergene intercrine cytokine family. Annu Rev Immunol 9:617–648, 1991 Kelner GS, Kennedy J, Bacon KB, Kleyensteuber S, Largaespada DA, Jenkins NA, Copeland NG, Bazan JF, Moore KW, Schall TJ, et al.: Lymphotactin: A cytokine that represents a new class of chemokine. Science 266:1395–1399, 1994 Eckmann L, Kagnoff MF, Fierer J: Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect Immun 61:4569–4574, 1993 Jung HC, Eckmann L, Yang SK, Panja A, Fierer J, Morzycka-Wroblewska E, Kagnoff MF: A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J Clin Invest 95:55–65, 1995 McCormick BA, Miller SI, Carnes D, Madara JL: Transepithelial signaling to neutrophils by Salmonellae: a novel virulence mechanism for gastroenteritis. Infect Immun 63:2302–2309, 1995 Sheth R, Anderson J, Sato T, Oh B, Hempson SJ, Rollo E, Mackow ER, Shaw RD: Rotavirus stimulates IL-8 secretion from cultured epithelial cells. Virology 221:251–259, 1996 Standiford TJ, Kunkel SL, Basha MA, Chensue SW, Lynch JP, Toews GP, Westwick J, Strieter RM: Interleukin-8 gene expression by a pulmonary epithelial cell line. A model for cytokine networks in the lung. J Clin Invest 86:1945–1953, 1990 Paine R, Rolfe MW, Standiford TJ, Burdick MD, Rollins BJ, Strieter RM: MCP-1 expression by rat type II alveolar epithelial cells in primary culture. J Immunol 150:4561–4570, 1993 Kagnoff MF, Eckmann L: Epithelial cells as sensors for microbial infection. J Clin Invest 100:6–10, 1997 Yang SK, Eckmann L, Panja A, Kagnoff MF: Differential and regulated expression of CXC, CC, and C-chemokines by human colon epithelial cells. Gastroenterology 113:1214–1223, 1997 Elewaut D, Didoanto JA, Kim JM, et al.: Nuclear factor-kB is a central regulator of the epithelial cell proinflammatory gene program after infection with invasive bacteria. Gastroenterology 116:G3071, 1999 Ohno Y, Lee J, Fusunyan RD, MacDermott RP, Sanderson IR: Macrophage inflammatory protein-2: Chromosomal regulation in rat small intestinal epithelial cells. Proc Natl Acad Sci USA 94:10279–10284, 1997 Fusunyan RD, Quinn JJ, Ohno Y, MacDermott, RP, Sanderson IR: Butyrate enhances interleukin-8 secretion by intestinal epithelial cells in response to interleukin-1β and lipopolysaccharide. Pediatr Res 43(1):84–90, 1998 Quinn JJ, Fusunyan RD, MacDermott RP, Sanderson IR: Butyrate switches the pattern of chemokine secretion by intestinal epithelial cells. Gastroenterology 110:A833, 1996 Rath HC, Herfarth HH, Ikeda JS, Grenther WB, Hamm TE, Balish E, Taurog JD, Hammer RE, Wilson KH, Sartor BR: Normal luminal bacteria, especially Bacterioides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats. J Clin Invest 98:945–953, 1996 Dwinell MB, Eckmann L, Leopard JD, Varki NM, Kagnoff MF: Chemokine Receptor Expression by Human Intestinal Epithelial Cells. Gastroenterology 117:359–367, 1999 Mahida YR, Ceska M, Effenberger F, Kurlak L, Lindley I, Hawkey CJ: Enhanced synthesis of neutrophil activating peptide-1/interleukin-8 in active ulcerative colitis. Clin Sci 82:273–275, 1992 Izzo RS, Witkon K, Chen AI, Hadjiyane C, Weinstein MI, Pellecchia C: Interleukin-8 and neutrophil markers in colonic mucosa from patients with ulcerative colitis. Am J Gastroenterol 87:1447–1452, 1992 Izzo RS, Witkon K, Chen AI, Hadjiyane C, Weinstein MI, Pellecchia C: Neutrophil-activating peptide (interleukin-8) in colonic mucosa from patients with Crohn's disease. Scand J Gastroenterol 28:296–300, 1993 Raab Y, Gerdin B, Ahlstedt S, Hallgren R: Neutrophil mucosal involvement is accompanied by enhanced local production of interleukin-8 in ulcerative colitis. Gut 34:1203–1206, 1993 Kesharvarzian A, Fusunyan RD, D'Astice M, Eiznhamer D, Sanderson IR, MacDermott RP: Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: Evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol 94:704–712, 1999 Ina K, Kusugami K, Yamaguchi T, Imada A, Hosokawa T, Ohsuga M, Shinoda M, Ando T, Ito K, Yokoyama Y: Mucosal interleukin-8 is involved in neutrophil migration and binding to extracellular matrix in inflammatory bowel disease. Am J Gastroenterol 92:1342–1346, 1997 Mitsuyama K, Toyonaga A, Sasaki E, Watanabe K, Tateishi H, Nishiyama T, Saiki T, Ikeda H, Tsuruta O, Tanikawa K: IL-8 is an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease. Clin Exp Immunol 96:432–436, 1994 Daig R, Andus T, Aschenbrenner E, Falk W, Scholmerich J, Gross V: Increased interleukin 8 expression in the colon mucosa of patients with inflammatory bowel disease. Gut 38:216–222, 1996 Mazzucchelli L, Hauser C, Z'graggen K, Wagner J, Hess M, Laissue JA, Mueller C: Expression of interleukin-8 gene in inflammatory bowel disease is related to the histological grade of active inflammation. Am J Pathol 144:997–1007, 1994 Izutani R, Ohyanagi H, MacDermott RP: Quantitative PCR for detection of femtogram quantities of interleukin-8 mRNA expression. Microbiol Immunol 38:233–237, 1994 Izutani R, Loh EY, Reinecker HC, Ohno Y, Fusunyan RD, Lichtenstein GR, Rombeau JL, MacDermott RP: Increased expression of interleukin-8 mRNA in ulcerative colitis and Crohn's disease mucosa and epithelial cells. Inflamm Bowel Dis 1:37–47, 1995 Grimm MC, Elsbury SKO, Pavli P, Doe WF: Interleukin 8: Cells of origin in inflammatory bowel disease. Gut 39:90–98, 1996 Arai F, Takahashi T, Furukawa K, Matsushima K, Asakura H: Mucosal expression of interleukin-6 and interleukin-8 messenger RNA in ulcerative colitis and Crohn's disease. Dig Dis Sci 43:2071–2079, 1999 Reinecker HC, Loh EY, Ringler DJ, Mehta A, Rombeau JL, MacDermott RP: Monocyte-chemoattrant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 108:40–50, 1995 Grimm MS, Elsbury SKO, Pavli P, Doe WF: Enhanced expression and production of monocyte chemoattractant protein-1 in inflammatory bowel disease mucosa. J Leukocyte Biol 56:804–812, 1996 Hausmann M, Spottl T, Falk W, Scholmerich J, Andus T, Rogler G: Differential substractive screening of CD33-positive macrophages from normal and inflamed mucosa. Gastroenterology 116:G3186, 1999 Mazzucchelli L, Hauser C, Z'graggen K, Wagner HE, Heiss MW, Laissue JA, Mueller C: Differential in situ expression of the genes encoding the chemokines MCP-1 and RANTES in human inflammatory bowel disease. J Pathol 178:201–206, 1996 Wedemeyer J, Lorentz A, Goke M, et al.: Enhanced production of monocyte chemotactic protein 3 in inflammatory bowel disease mucosa. Gut 44:629–635, 1999 Z'Graggen, Walz A, Mazzucchelli L, Streiter RM, Mueller C: The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease. Gastroenterology 113:808–816, 1997