Chemokines: Critical Regulators of Memory T Cell Development, Maintenance, and Function

Amsen, 2013, Decisions on the road to memory, Vol. 785, 107 Anderson, 2014, Intravascular staining for discrimination of vascular and tissue leukocytes, Nature Protocols, 9, 209, 10.1038/nprot.2014.005 Anderson, 2012, Cutting edge: Intravascular staining redefines lung CD8 T cell responses, Journal of Immunology, 189, 2702, 10.4049/jimmunol.1201682 Ariotti, 2014, T cell memory. Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert, Science, 346, 101, 10.1126/science.1254803 Arsenio, 2015, Asymmetric cell division in T lymphocyte fate diversification, Trends in Immunology, 36, 670, 10.1016/j.it.2015.09.004 Bergsbaken, 2015, Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8+ T cells responding to infection, Nature Immunology, 16, 406, 10.1038/ni.3108 Boylston, 2012, The origins of inoculation, Journal of the Royal Society of Medicine, 105, 309, 10.1258/jrsm.2012.12k044 Bromley, 2013, Recirculating memory T cells are a unique subset of CD4+ T cells with a distinct phenotype and migratory pattern, Journal of Immunology, 190, 970, 10.4049/jimmunol.1202805 Buchholz, 2013, Disparate individual fates compose robust CD8+ T cell immunity, Science, 340, 630, 10.1126/science.1235454 Carbone, 2015, Tissue-resident memory T cells and fixed immune surveillance in nonlymphoid organs, Journal of Immunology, 195, 17, 10.4049/jimmunol.1500515 Carbone, 2013, Distinct resident and recirculating memory T cell subsets in non-lymphoid tissues, Current Opinion in Immunology, 25, 329, 10.1016/j.coi.2013.05.007 Casey, 2012, Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues, Journal of Immunology, 188, 4866, 10.4049/jimmunol.1200402 Castellino, 2006, Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction, Nature, 440, 890, 10.1038/nature04651 Clark, 2006, The vast majority of CLA+ T cells are resident in normal skin, Journal of Immunology, 176, 4431, 10.4049/jimmunol.176.7.4431 Collins, 2016, Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation, Nature Communications, 7, 11514, 10.1038/ncomms11514 Cui, 2009, Effects of signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation, Vaccine, 27, 2177, 10.1016/j.vaccine.2009.01.088 D'Souza, 2006, Cutting edge: Latecomer CD8 T cells are imprinted with a unique differentiation program, Journal of Immunology, 177, 777, 10.4049/jimmunol.177.2.777 Dufour, 2002, IFN-gamma-inducible protein 10 (IP-10; CXCL10)-deficient mice reveal a role for IP-10 in effector T cell generation and trafficking, Journal of Immunology, 168, 3195, 10.4049/jimmunol.168.7.3195 Fadel, 2008, CXCR3-deficiency protects influenza-infected CCR5-deficient mice from mortality, European Journal of Immunology, 38, 3376, 10.1002/eji.200838628 Gattinoni, 2005, Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells, The Journal of Clinical Investigation, 115, 1616, 10.1172/JCI24480 Gerlach, 2016, The chemokine receptor CX3CR1 defines three antigen-experienced CD8 T cell subsets with distinct roles in immune surveillance and homeostasis, Immunity, 45, 1270, 10.1016/j.immuni.2016.10.018 Gerlach, 2013, Heterogeneous differentiation patterns of individual CD8+ T cells, Science, 340, 635, 10.1126/science.1235487 Gerritsen, 2016, The memory of a killer T cell: Models of CD8(+) T cell differentiation, Immunology and Cell Biology, 94, 236, 10.1038/icb.2015.118 Glennie, 2017, Skin-resident CD4+ T cells protect against Leishmania major by recruiting and activating inflammatory monocytes, PLoS Pathogens, 13, 10.1371/journal.ppat.1006349 Glennie, 2015, Skin-resident memory CD4+ T cells enhance protection against Leishmania major infection, The Journal of Experimental Medicine, 212, 1405, 10.1084/jem.20142101 Griffith, 2014, Chemokines and chemokine receptors: Positioning cells for host defense and immunity, Annual Review of Immunology, 32, 659, 10.1146/annurev-immunol-032713-120145 Groom, 2012, CXCR3 chemokine receptor-ligand interactions in the lymph node optimize CD4+ T helper 1 cell differentiation, Immunity, 37, 1091, 10.1016/j.immuni.2012.08.016 Hancock, 2000, Requirement of the chemokine receptor CXCR3 for acute allograft rejection, Journal of Experimental Medicine, 192, 1515, 10.1084/jem.192.10.1515 Harrington, 2008, Memory CD4 T cells emerge from effector T-cell progenitors, Nature, 452, 356, 10.1038/nature06672 Hokeness, 2007, CXCR3-dependent recruitment of antigen-specific T lymphocytes to the liver during murine cytomegalovirus infection, Journal of Virology, 81, 1241, 10.1128/JVI.01937-06 Homey, 2002, CCL27-CCR10 interactions regulate T cell-mediated skin inflammation, Nature Medicine, 8, 157, 10.1038/nm0202-157 Hu, 2011, Expression of chemokine receptor CXCR3 on T cells affects the balance between effector and memory CD8 T-cell generation, Proceedings of the National Academy of Sciences of the United States of America, 108, E118, 10.1073/pnas.1101881108 Iijima, 2014, T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells, Science, 346, 93, 10.1126/science.1257530 Jiang, 2012, Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity, Nature, 483, 227, 10.1038/nature10851 Joshi, 2007, Inflammation directs memory precursor and short-lived effector CD8(+) T cell fates via the graded expression of T-bet transcription factor, Immunity, 27, 281, 10.1016/j.immuni.2007.07.010 Kaech, 2012, Transcriptional control of effector and memory CD8+ T cell differentiation, Nature Reviews. Immunology, 12, 749, 10.1038/nri3307 Kaech, 2003, Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells, Nature Immunology, 4, 1191, 10.1038/ni1009 Kalia, 2010, Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo, Immunity, 32, 91, 10.1016/j.immuni.2009.11.010 Kastenmüller, 2013, Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node, Immunity, 38, 502, 10.1016/j.immuni.2012.11.012 Kohlmeier, 2011, Inflammatory chemokine receptors regulate CD8(+) T cell contraction and memory generation following infection, The Journal of Experimental Medicine, 208, 1621, 10.1084/jem.20102110 Kurachi, 2011, Chemokine receptor CXCR3 facilitates CD8(+) T cell differentiation into short-lived effector cells leading to memory degeneration, The Journal of Experimental Medicine, 208, 1605, 10.1084/jem.20102101 Laidlaw, 2016, The multifaceted role of CD4(+) T cells in CD8(+) T cell memory, Nature Reviews. Immunology, 16, 102, 10.1038/nri.2015.10 Lycke, 2012, Recent progress in mucosal vaccine development: Potential and limitations, Nature Reviews. Immunology, 12, 592, 10.1038/nri3251 Mackay, 2013, The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin, Nature Immunology, 14, 1294, 10.1038/ni.2744 Marriott, 2017, Retention of ag-specific memory CD4+ T cells in the draining lymph node indicates lymphoid tissue resident memory populations, European Journal of Immunology, 47, 860, 10.1002/eji.201646681 Marshall, 2011, Differential expression of Ly6C and T-bet distinguish effector and memory Th1 CD4(+) cell properties during viral infection, Immunity, 35, 633, 10.1016/j.immuni.2011.08.016 Nakanishi, 2009, CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell help, Nature, 462, 510, 10.1038/nature08511 Opferman, 1999, Linear differentiation of cytotoxic effectors into memory T lymphocytes, Science, 283, 1745, 10.1126/science.283.5408.1745 O'Shea, 2010, Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells, Science, 327, 1098, 10.1126/science.1178334 Pipkin, 2010, Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells, Immunity, 32, 79, 10.1016/j.immuni.2009.11.012 Pollizzi, 2016, Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation, Nature Immunology, 17, 704, 10.1038/ni.3438 Potsch, 1999, Distinct migration patterns of naive and effector CD8 T cells in the spleen: Correlation with CCR7 receptor expression and chemokine reactivity, European Journal of Immunology, 29, 3562, 10.1002/(SICI)1521-4141(199911)29:11<3562::AID-IMMU3562>3.0.CO;2-R Pozsgay, 2017, Antigen-specific immunotherapies in rheumatic diseases, Nature Reviews. Rheumatology, 13, 525, 10.1038/nrrheum.2017.107 Rosenblum, 2010, CXC chemokine ligand (CXCL) 9 and CXCL10 are antagonistic costimulation molecules during the priming of alloreactive T cell effectors, Journal of Immunology, 184, 3450, 10.4049/jimmunol.0903831 Sallusto, 1999, Switch in chemokine receptor expression upon TCR stimulation reveals novel homing potential for recently activated T cells, European Journal of Immunology, 29, 2037, 10.1002/(SICI)1521-4141(199906)29:06<2037::AID-IMMU2037>3.0.CO;2-V Sallusto, 1999, Two subsets of memory T lymphocytes with distinct homing potentials and effector functions, Nature, 401, 708, 10.1038/44385 Sallusto, 1998, Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes, Journal of Experimental Medicine, 187, 875, 10.1084/jem.187.6.875 Sarkar, 2008, Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates, The Journal of Experimental Medicine, 205, 625, 10.1084/jem.20071641 Schenkel, 2014, Cutting edge: Resident memory CD8 T cells occupy frontline niches in secondary lymphoid organs, Journal of Immunology, 192, 2961, 10.4049/jimmunol.1400003 Schenkel, 2013, Sensing and alarm function of resident memory CD8+ T cells, Nature Immunology, 14, 509, 10.1038/ni.2568 Schenkel, 2014, Tissue-resident memory T cells, Immunity, 41, 886, 10.1016/j.immuni.2014.12.007 Shin, 2012, A vaccine strategy that protects against genital herpes by establishing local memory T cells, Nature, 491, 463, 10.1038/nature11522 Soudja, 2014, Memory-T-cell-derived interferon-γ instructs potent innate cell activation for protective immunity, Immunity, 40, 974, 10.1016/j.immuni.2014.05.005 Sprent, 2002, T cell memory, Annual Review of Immunology, 20, 551, 10.1146/annurev.immunol.20.100101.151926 Stary, 2015, VACCINES. A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells, Science, 348, 10.1126/science.aaa8205 Sung, 2012, Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes, Cell, 150, 1249, 10.1016/j.cell.2012.08.015 Tabatabaian, 2017, Biologic and new therapies in asthma, Immunology and Allergy Clinics of North America, 37, 329, 10.1016/j.iac.2017.01.007 Thapa, 2009, CXCR3 deficiency increases susceptibility to genital herpes simplex virus type 2 infection: Uncoupling of CD8+ T-cell effector function but not migration, Journal of Virology, 83, 9486, 10.1128/JVI.00854-09 Thucydides, 1634 Tse, 2014, The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8+ T cells specific for infectious pathogens, The Journal of Infectious Diseases, 210, 1508, 10.1093/infdis/jiu281 Tubo, 2014, CD4+ T cells: Guardians of the phagosome, Clinical Microbiology Reviews, 27, 200, 10.1128/CMR.00097-13 Tubo, 2013, Single naive CD4+ T cells from a diverse repertoire produce different effector cell types during infection, Cell, 153, 785, 10.1016/j.cell.2013.04.007 Ugur, 2014, Resident CD4+ T cells accumulate in lymphoid organs after prolonged antigen exposure, Nature Communications, 5, 4821, 10.1038/ncomms5821 Verbist, 2016, Metabolic maintenance of cell asymmetry following division in activated T lymphocytes, Nature, 532, 389, 10.1038/nature17442 Wakim, 2012, The molecular signature of tissue resident memory CD8 T cells isolated from the brain, Journal of Immunology, 189, 3462, 10.4049/jimmunol.1201305 Whiting, 2004, Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production, Journal of Immunology, 172, 7417, 10.4049/jimmunol.172.12.7417 Wolfe, 2017, Biologic therapies for autoimmune and connective tissue diseases, Immunology and Allergy Clinics of North America, 37, 283, 10.1016/j.iac.2017.01.005 Yang, 2011, The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets, Nature Immunology, 12, 1221, 10.1038/ni.2158 Zaid, 2017, Chemokine receptor-dependent control of skin tissue-resident memory T cell formation, Journal of Immunology, 199, 2451, 10.4049/jimmunol.1700571 Zhang, 2008, CXCR3 mediates region-specific antiviral T cell trafficking within the central nervous system during West Nile virus encephalitis, Journal of Immunology, 180, 2641, 10.4049/jimmunol.180.4.2641