Chemistry of the calcitonins

Wimalawansa, 1990, Calcitonin: Molecular biology, physiology, pathophysiology, and its therapeutic uses, 121 Rosenblatt, 1982, Structure activity relations in the calcium-regulating peptide hormone, 103 Morikawa, 1976, Synthesis of eel-calcitonin and (asu1,7)-eel-calcitonin: contribution of the disulfide bond to the hormonal activity, Experientia, 32, 1104, 10.1007/BF01927568 Orlowski, 1987, Biologically potent analogues of salmon caltitonin which do not contain an N-terminal disulfide-bridged ring structure, Eur J Biochem, 162, 399, 10.1111/j.1432-1033.1987.tb10615.x Yates, 1990, A noncyclical analog of salmon calcitonin (Na-propionyl Di-Ala1,7, des-Leu19 sCT) retains full potency without inducing anorexia in rats, Endocrinology, 126, 2845, 10.1210/endo-126-6-2845 Moe, 1985, Design synthesis and characterization of a model peptide having potent calcitonin-like biological activity: implications for calcitonin structure/activity, Biochemistry, 24, 1971, 10.1021/bi00329a026 Epand, 1988, Deletion sequences of salmon calcitonin that retain the essential biological and conformational features of the intact molecule, J Med Chem, 31, 1595, 10.1021/jm00403a019 Epand, 1990, Study of a series of analogs of salmon calcitonin in which alanine replaces leucine, Eur J Biochem, 188, 633, 10.1111/j.1432-1033.1990.tb15444.x Twery, 1988, Analogue separates biological effects of salmon calcitonin on brain and renal cortical membranes, Europ J Pharmacol, 155, 285, 10.1016/0014-2999(88)90515-8 Juppner, 1991, A receptor for parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) is a novel, G proteinlinked receptor, Science, 10.1126/science.1658941 Lin, 1991, Expression cloning of a calcitonin receptor, a novel adenylate cyclase-coupled receptor, Science, 10.1126/science.1658940