Chemical modification of pro-inflammatory proteins by peroxynitrite increases activation of TLR4 and NF-κB: Implications for the health effects of air pollution and oxidative stress

Redox Biology - Tập 37 - Trang 101581 - 2020
Kira Ziegler1, Anna T. Kunert1, Kathrin Reinmuth-Selzle1, Anna Lena Leifke1, Darius Widera2, Michael G. Weller3, Detlef Schuppan4,5, Janine Fröhlich-Nowoisky1, Kurt Lucas1, Ulrich Pöschl1
1Max Planck Institute for Chemistry, Multiphase Chemistry Department, 55128, Mainz, Germany
2Stem Cell Biology and Regenerative Medicine Group, School of Pharmacy, University of Reading, RG6 6AP, Reading, UK
3Federal Institute for Materials Research and Testing (BAM), Berlin, Germany
4Institute of Translational Immunology, University Medical Center of the Johannes Gutenberg University, 55131, Mainz, Germany
5Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, MA, 02215, USA

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