Chemical and pharmacological evaluation of Manglicolous lichen Graphis ajarekarii PATW. & C. R. KULK.

Vietnam Journal of Science and Technology - Tập 57 Số 3 - Trang 300-308 - 2019
Polimati Haritha1, Sunil Kumar Patnaik2, Vinay Bharadwaj Tatipamula1
1Pharmaceutical Sciences Department, AU College of Pharmaceutical Sciences, Andhra University, Visakhapatnam – 530 003, Andhra Pradesh, India
2Department of Pharmaceutical Chemistry, JSS College of Pharmacy, Ootacamund- 643 001, Tamil Nadu, India

Tóm tắt

The chemical examination of ethanolic extract of manglicolous lichen Graphis ajarekarii (Ga-Et) resulted in isolation of three known metabolites – chiodectonic acid (1), graphenone (2) and graphisquinone (3). All the isolates (1-3) and Ga-Et were screened against DPPH and superoxide free radicals, six different cancer cell lines and one normal human cell line (NHME). This work is the first report of antioxidant and cytotoxicity studies on the isolated metabolites (1-3).

Từ khóa

#manglicolous lichen #antioxidant #cancer #Sulforhodamine B assay

Tài liệu tham khảo

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Thông tin xuất bản

Vietnam Journal of Science and Technology

Tập 57 Số 3

300-308

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