Betül Demırcı1,2, Mehmet Yaşar Dadandı3, D. Paper1, Gerhard Franz1, K. Hüsnü Can Başer2
1Department of Pharmaceutical Biology, Faculty of Chemistry and Pharmacy, University of Regensburg, 93040 Regensburg, Germany
2Department of Pharmacognosy, Faculty of Pharmacy, Anadolu University, 26470 Eskişehir, Turkey
3Department of Biology, Faculty of Science and Letters, Erciyes University, 38039 Kayseri, Turkey
Tóm tắt
AbstractPhlomis linearis Boiss. & Bal. of the Lamiaceae family growing in central, east and southeast Anatolia is an endemic species for Turkey. The essential oil obtained from the aerial parts by hydro distillation was subsequently analyzed by GC/MS. The main components of the oil were found as β-caryophyllene (24.2%), germacrene D (22.3%) and caryophyllene oxide (9.2%), among 49 identified compounds, representing 94.5% of the total essential oil. The overall biological activity of the essential oil (100 μg/pellet) was tested on the chorioallantoic membrane (CAM) of the fertilized hen’s egg in order to examine the anti-angiogenic and anti-inflammatory activity. None of the tests showed pronounced activity, toxicity or irritation at the tested concentration.
