Characterization of the mutational profile of (+)-7 R ,8 S -dihydroxy-9 S ,10 R -epoxy-7,8,9,10-tetrahydrobenzo[ a ]pyrene at the hypoxanthine (guanine) phosphoribosyltransferase gene in repair-deficient Chinese hamster V-H1 cells
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Wei,S.-J.C., Chang,R.L., Wong,C.Q., Bhachech,N., Cui,X.X., Hennig,E., Yagi,H., Sayer,J.M., Jerina,D.M., Preston,B.D. and Conney,A.H. ( 1991 ) Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[ a ]pyrene. Proc. Natl Acad. Sci. USA , 88 , 11227 –11230.
Wei,S.-J.C., Chang,R.L., Bhachech,N., Cui,X.X., Merkler,K.A., Wong,C.Q., Hennig,E., Yagi,H., Jerina,D.M. and Conney,A.H. ( 1993 ) Dose-dependent differences in the profile of mutations induced by (+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[ a ]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells. Cancer Res. , 53 , 3294 –3301.
Hennig,E., Conney,A.H. and Wei,S.-J.C. ( 1995 ) Characterization of hprt splicing mutations induced by the ultimate carcinogenic metabolite of benzo[ a ]pyrene in Chinese hamster V-79 cells. Cancer Res. , 55 , 1550 –1558.
Wei,S.-J.C., Chang,R.L., Cui,X.X., Merkler,K.A., Wong,C.Q., Yagi,H., Jerina,D.M. and Conney,A.H. ( 1996 ) Dose-dependent differences in the mutational profiles of (–)-(1R,2S,3S,4R)-3,4-dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenzo[ c ]phenanthrene and its less carcinogenic enantiomer. Cancer Res. , 56 , 3695 –3703.
Buening,M.K., Wislocki,P.G., Levin,W., Yagi,H., Thakker,D.R., Akagi,H., Koreeda,M., Jerina,D.M. and Conney,A.H. ( 1978 ) Tumorigenicity of the optical enantiomers of the diastereomeric benzo[ a ]pyrene 7,8,-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7β,8α-dihydroxy-9α,10α-epoxy-7,8,9,10-tetrahydrobenzo[ a ]pyrene. Proc. Natl Acad. Sci. USA , 75 , 5358 –5361.
Slaga,T.J., Bracken,W.J., Gleason,G., Levin,W., Yagi,H., Jerina,D.M. and Conney,A.H. ( 1979 ) Marked differences in the tumor-initiating activities of the optical enantiomers of the diasteriomeric benzo[ a ]pyrene 7,8-diol-9,10-epoxides. Cancer Res. , 39 , 67 –71.
Wood,A.W., Chang,R.L., Levin,W., Thakker,D.R., Yagi,H., Sayer,J.M., Jerina,D.M. and Conney,A.H. ( 1984 ) Mutagenicity of the enantiomers of the diasteriomeric bay-region benzo[ c ]phenanthrene 3,4-diol-1,2-epoxides in bacterial and mammalian cells. Cancer Res. , 44 , 2320 –2324.
Levin,W., Chang,R.L., Wood,A.W., Thakker,D.R., Yagi,H., Jerina,D.M. and Conney,A.H. ( 1986 ) Tumorigenicity of optical isomers of the diasteriomeric bay-region 3,4-diol-1,2-epoxides of benzo[ c ]phenanthrene in murine tumor models. Cancer Res. , 46 , 2257 –2261.
Jerina,D.M., Yagi,H., Thakker,D.R., Sayer,J.M., van Bladeren,P.J., Lehr,R.E., Whalen,D.L., Levin,W., Chang,R.L., Wood,A.W. and Conney,A.H. (1984) Identification of the ultimate carcinogenic metabolites of the polycyclic aromatic hydrocarbons: bay-region (R,S)-diol-(S,R)-epoxides. In Caldwell,J. and Paulson,G.D. (eds) Foreign Compound Metabolism . Taylor and Francis, London, UK, pp. 257–266.
Cheng,S.C., Hilton,B.D., Roman,J.M. and Dipple,A. ( 1989 ) DNA adducts from carcinogenic and noncarcinogenic enantiomers of benzo[ a ]pyrene dihydrodiol epoxide. Chem. Res. Toxicol. , 2 , 334 –340.
Sayer,J.M., Chadha,A., Agarwal,S.K., Yeh,H.J.C., Yagi,H. and Jerina,D.M. ( 1991 ) Covalent nucleoside adducts of benzo[ a ]pyrene 7,8-diol-9,10-epoxides: structural reinvestigation and characterization of a novel adenosine adduct on the ribose moiety. J. Org. Chem. , 56 , 20 –29.
Dipple,A., Pigott,M.A., Agarwal,S.K., Yagi,H., Sayer,J.M. and Jerina,D.M. ( 1987 ) Optically active benzo[ c ]phenanthrene diol epoxides bind extensively to adenine in DNA. Nature , 327 , 535 –536.
Jerina,D.M., Sayer,J.M., Agarwal,S.K., Yagi,H., Levin,W., Wood,A.W., Conney,A.H., Pruess-Schwartz,D., Baird,W.M., Pigott,M.A. and Dipple,A. (1986) Reactivity and tumorigenicity of bay-region diol epoxides derived from polycyclic aromatic hydrocarbons. In Kocsis,J.J., Jollow,D.J., Witmer,C.M., Nelson,J.O. and Snyder,R. (eds) Biological Reactive Intermediates III . Plenum, New York, NY, pp. 11–30.
Wood,R.D. and Shivji,M.K.K. ( 1997 ) Which DNA polymerases are used for DNA-repair in eukaryotes? Carcinogenesis , 18 , 605 –610.
Loechler,E.L. ( 1996 ) The role of adduct site-specific mutagenesis in understanding how carcinogen–DNA adducts cause mutations: perspective, prospects and problems. Carcinogenesis , 17 , 895 –902.
Zdzienicka,M.Z. and Simons,J.W.I.M. ( 1987 ) Mutagen-sensitive cell lines are obtained with a high frequency in V79 Chinese hamster cells. Mutat. Res. , 178 , 235 –244.
Collins,A.R. ( 1993 ) Mutant rodent cell lines sensitive to ultraviolet light, ionizing radiation and cross-linking agents: a comprehensive survey of genetic and biochemical characteristics. Mutat. Res. DNA Repair , 293 , 99 –118.
Kadkhodayan,S., Salazar,E.P., Ramsey,M.J., Takayama,K., Zdzienicka,M., Tucker,J.D. and Weber,C.A. ( 1997 ) Molecular analysis of ERCC2 mutations in the repair deficient hamster mutants UVL-1 and V-H1. Mutat. Res. , 385 , 47 –57.
Hoeijmakers,J.H.J., Egly,J.-M. and Vermeulen,W. ( 1996 ) TFIIH: a key component in multiple DNA transactions. Curr. Opin. Genet. Dev. , 6 , 26 –33.
Mitchell,D.L., Zdzienicka,M.Z., van Zeeland,A.A. and Nairn,R.S. ( 1989 ) Intermediate (6–4) photoproduct repair in Chinese hamster V79 mutant V-H1 correlates with intermediate levels of DNA incision and repair replication. Mutat. Res. , 226 , 43 –47.
Vrieling,H., Van Rooijen,M.L., Groen,N.A., Zdzienicka,M.Z., Simons,J.W.I.M., Lohman,P.H.M. and van Zeeland,A.A. ( 1989 ) DNA strand specificity for UV-induced mutations in mammalian cells. Mol. Cell. Biol. , 9 , 1277 –1283.
Yagi,H., Akagi,H., Thakker,D.R., Mah,H.D., Koreeda,M. and Jerina,D.M. ( 1977 ) Absolute stereochemistry of the highly mutagenic 7,8-diol 9,10-epoxides derived from the potent carcinogen trans-7,8-dihydroxy-7,8-dihydrobenzo[ a ]pyrene. J. Am. Chem. Soc. , 99 , 2358 –2359.
Wei,S.-J.C., Chang,R.L., Hennig,E., Cui,X.X., Merkler,K.A., Wong,C.Q., Yagi,H., Jerina,D.M. and Conney,A.H. ( 1994 ) Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[ a ]pyrene 7,8-diol-9,10-epoxide enantiomers with high and low carcinogenic activity. Carcinogenesis , 15 , 1729 –1735.
SAS Institute Inc. (1985) SAS®User's Guide, Statistics , 5th Edn. SAS Institute Inc., Cary, NC.
Chen,J. and Thilly,W.G. ( 1996 ) Mutational spectra vary with exposure conditions: benzo[ a ]pyrene in human cells. Mutat. Res. , 357 , 209 –217.
Brookes,P. and Osborne,M.R. ( 1982 ) Mutation in mammalian cells by stereoisomers of anti-benzo[ a ]pyrene-diolepoxide in relation to the extent and nature of the DNA reaction products. Carcinogenesis , 3 , 1223 –1226.
Zdzienicka,M.Z., van der Schans,G.P., Westerveld,A., van Zeeland,A.A. and Simons,J.W.I.M. ( 1988 ) Phenotypic heterogeneity within the first complementation group of UV-sensitive mutants of Chinese hamster cell lines. Mutat. Res. , 193 , 31 –41.