Characterization of the Neuroanatomical Distribution of Agouti-Related Protein Immunoreactivity in the Rhesus Monkey and the Rat*

Endocrinology - Tập 140 Số 3 - Trang 1408-1415 - 1999
Carrie Haskell‐Luevano1, Peilin Chen1, Chien Li1, Kang‐Wei Chang2, M. Susan Smith1, Judy L. Cameron1, Roger D. Cone1
1Vollum Institute (C.H.-L., R.D.C.), Oregon Regional Primate Research Center (P.C., C.L., M.S.S., J.C.) Oregon Health Sciences University, Portland, Oregon 97201
2Phoenix Pharmaceuticals, Inc. (K.C.), Mountain View, California 94043

Tóm tắt

Từ khóa


Tài liệu tham khảo

Watson, 1978, Evidence for two separate opiate peptide neuronal systems and the coexistence of β-lipotropin, β-endorphin, and ACTH immunoreactivities in the same hypothalamic neurons., Nature, 275, 226, 10.1038/275226a0

Jacobowitz, 1978, α-Melanocyte stimulating hormone: immunohistochemical identification and mapping in neurons of rat brain., Proc Natl Acad Sci USA, 75, 6300, 10.1073/pnas.75.12.6300

Nilaver, 1979, Adrenocorticotropin and beta-lipotropin in the hypothalamus. Localization in the same arcuate neurons by sequential immunocytochemical procedures., J Cell Biol, 81, 50

Joseph, 1983, Immunocytochemical localization of ACTH parikarya in nucleus tractus solitarius: evidence for a second opiocortin neuronal system., Neurosci Lett, 38, 221, 10.1016/0304-3940(83)90372-5

Palkovits, 1987, Pro-opiomelanocortin-derived peptides (ACTH/β-endorphin/α-MSH) in brainstem baroreceptor areas of the rat., Brain Res, 436, 323, 10.1016/0006-8993(87)91676-3

Tatro, 1990, Melanotropin receptors in the brain are differentially distributed and recognize both corticotropin andα -melanocyte stimulating hormone., Brain Res, 536, 124, 10.1016/0006-8993(90)90016-5

Tatro, 1994, Distribution of melanocortin receptors in the lower brainstem of the rat., Ann NY Acad Sci, 739, 311, 10.1111/j.1749-6632.1994.tb19833.x

Mountjoy, 1994, Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control cirsuits in the brain., Mol Endocrinol, 8, 1298

Roselli-Rehfuss, 1993, Identification of a receptor for γ-MSH and other proopiomelanocortin peptides in the hypothalamus and limbic system., Proc Natl Acad Sci USA, 90, 8856, 10.1073/pnas.90.19.8856

Gantz, 1993, Molecular cloning of a novel melanocortin receptor., J Biol Chem, 268, 8246, 10.1016/S0021-9258(18)53088-X

Gantz, 1993, Molecular cloning, expression, and gene localization of a fourth melanocortin receptor., J Biol Chem, 268, 15174, 10.1016/S0021-9258(18)82452-8

Shutter, 1997, Hypothalamic expression of ART, a novel gene related to agouti, is upregulated in obese and diabetic mutant mice., Genes Dev, 11, 593, 10.1101/gad.11.5.593

Ollmann, 1997, Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein., Science, 278, 135, 10.1126/science.278.5335.135

Lu, 1994, Agouti protein is an antagonist of the melanocyte-stimulating hormone receptor., Nature, 371, 799, 10.1038/371799a0

Miller, 1993, Cloning of the mouse agouti gene predicts a novel secreted protein ubiquitously expressed in mice carrying the lethal yellow (Ay) mutation., Genes Dev, 7, 454, 10.1101/gad.7.3.454

Bultman, 1994, Molecular analysis of reverse mutations from nonagouti (a) to black-and-tan (at) and white-bellied agouti (Aw) reveals alternative forms of agouti transcripts., Genes Dev, 8, 481, 10.1101/gad.8.4.481

Yen, 1994, Obesity, diabetes, and neoplasia in yellow Avy/− mice: ectopic expression of the agouti gene., FASEB J, 8, 479, 10.1096/fasebj.8.8.8181666

Fan, 1997, Role of melanocortinergic neurons in feeding and the agouti obesity syndrome., Nature, 385, 165, 10.1038/385165a0

Huszar, 1997, Targeted disruption of the melanocortin-4 receptor results in obesity in mice., Cell, 88, 131, 10.1016/S0092-8674(00)81865-6

Fong, 1997, ART (protein product of agouti-related transcript) as an antagonist of MC-3 and MC-4 receptors., Biochem Biophys Res Commun, 237, 629, 10.1006/bbrc.1997.7200

Graham, 1997, Overexpression of Agrt leads to obesity in transgenic mice., Nat Genet, 17, 273, 10.1038/ng1197-273

Wolff, 1990, 445

Von Frijtag, 1998, The role of central melanocortin receptors in the activation of the hypothalamus-pituitary-adrenal-axis and the induction of excessive grooming., Br J Pharmacol, 123, 1503, 10.1038/sj.bjp.0701750

Huang, 1997, Antipyretic role of endogenous melanocortins mediated by central melanocortin receptors during endotoxin-induced fever., J Neurosci, 17, 3343, 10.1523/JNEUROSCI.17-09-03343.1997

Li, 1996, Melanocortin antagonists define two distinct pathways of cardiovascular control by α- andγ -melanocyte-stimulating hormones., J Neurosci, 16, 5182, 10.1523/JNEUROSCI.16-16-05182.1996

Schreihofer, 1993, Reversal of fasting-induced suppression of luteinizing hormone (LH) secretion in male rhesus monkey by intragastric nutrient infusion: evidence of rapid stimulation of LH by nutritional signals., Endocrinology, 132, 1890, 10.1210/endo.132.5.8477642

Cameron, 1991, Slowing of pulsatile LH and testosterone secretion during short-term fasting in adult male rhesus monkeys (Macaca mulatta)., Endocrinology, 128, 1532, 10.1210/endo-128-3-1532

Johansson, 1983, Enhancement of immunoperoxidase staining using osmium tetroxide., J Neurosci Methods, 7, 185, 10.1016/0165-0270(83)90081-X

Arriza, 1988, The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response., Neuron, 1, 887, 10.1016/0896-6273(88)90136-5

Quillan, 1998, A synthetic human agouti-related protein-(83–132)-NH2 fragment is a potent inhibitor of melanocortin receptor function., FEBS Lett, 428, 59, 10.1016/S0014-5793(98)00487-6

Finley, 1981, Immunocytochemical localization of β-endorphin-containing neurons in the rat brain., Neuroendocrinology, 33, 28, 10.1159/000123197

Khachaturian, 1984, Proopiomelanocortin peptide immunocytochemistry in rhesus monkey brain., Brain Res Bull, 13, 785, 10.1016/0361-9230(84)90237-5

Watson, 1977, β-Lipotropin: Localization of cells and axons in rat brain by immunocytochemistry., Proc Natl Acad Sci USA, 74, 5155, 10.1073/pnas.74.11.5155

Low, 1994, Receptors for the melanocortin peptides in the central nervous system., Curr Opin Endocrinol Diabetes, 1, 79, 10.1097/00060793-199400010-00016

Mizuno, 1998, Hypothalamic pro-opiomelanocortin mRNA is reduced by fasting and corrected in ob/ob and db/db mice, but is stimulated by leptin., Diabetes, 47, 294, 10.2337/diab.47.2.294

Thornton, 1997, Regulation of hypothalamic proopiomelanocortin mRNA by leptin in ob/ob mice., Endocrinology, 138, 5063, 10.1210/endo.138.11.5651

Paxinos, 1997

Bleier, 1984

Broberger, Proc Natl Acad Sci USA, 95, 15043, 10.1073/pnas.95.25.15043