Characteristics of coronary artery ectasia and accompanying plaques: an optical coherence tomography study

The International Journal of Cardiovascular Imaging
Yu Hou1, Jihong Dai1, Hao Tang2, Chao Fang1, Shuang Jiang1, Xueming Xu1, Bo Yu1, Yingfeng Tu2
1Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China
2The First Affiliated Hospital of Harbin Medical University, Harbin, China

Tóm tắt

AbstractCoronary artery ectasia (CAE) in adults is often caused by atherosclerotic plaques. CAE can affect atherosclerotic plaques through hemodynamic changes. However, no study has evaluated the characteristics of CAE with atherosclerotic plaques. Therefore, we aimed to disclose the characteristics of atherosclerotic plaques in patients with CAE using optical coherence tomography (OCT). We evaluated patients with CAE, confirmed by coronary angiography, who underwent pre-intervention OCT between April 2015 and April 2021. Each millimeter of the OCT images was analyzed to assess the characteristics of CAEs, plaque phenotypes, and plaque vulnerability. A total of 286 patients (344 coronary vessels) met our criteria, 82.87% of whom were men. Right coronary artery lesions were the most common, comprising 44.48% (n = 153) of the total. We found 329 CAE vessels with plaques, accounting for 95.64% of the coronary vessels. After grouping CAEs and plaques by their relative positions, we found that the length of plaques within CAE lesions was longer than that of plaques in other sites (P < 0.001). Plaques within CAE lesions had greater maximum lipid angles and lipid indexes (P = 0.007, P = 0.004, respectively) than those on other sites. This study revealed the most common vascular and morphological characteristics of CAE. While the accompanying plaques were not affected by the location or morphology of the CAE vessels, they were affected by their position relative to the CAE lesion.

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The International Journal of Cardiovascular Imaging

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