Changes in plasma carotenoid, alpha-tocopherol, and lipid peroxide levels in response to supplementation with concentrated fruit and vegetable extracts: a pilot study

Di Mascio, 1993, Antioxidants defense systems: The role of carotenoids, tocopherols, and thiols, Am J Clin Nutr, 53, 194S, 10.1093/ajcn/53.1.194S Ames, 1993, Oxidants, antioxidants, and the degenerative diseases of aging, Proc Natl Acad Sci USA, 90, 7915, 10.1073/pnas.90.17.7915 Chopra, 1993, Free radical scavenging of lutein in vitro, Ann New York Acad Sci, 691, 246, 10.1111/j.1749-6632.1993.tb26184.x Lim, 1992, Antioxidant activity on xanthophylls on peroxyl radical-mediated phospholipid peroxidation, Biochim Biophys Acta, 1126, 178, 10.1016/0005-2760(92)90288-7 Di Mascio, 1989, Lycopene as the most efficient biological carotenoid singlet oxygen quencher, Arch Biochem Biophys, 274, 532, 10.1016/0003-9861(89)90467-0 Sies, 1992, Antioxidant functions of vitamins. Vitamins E and C, beta carotene, and other carotenoids, Ann New York Acad Sci, 669, 7, 10.1111/j.1749-6632.1992.tb17085.x Morris, 1994, Serum carotenoids and coronary heart disease. The Lipid Research Clinics Coronary Primary Prevention Trial and Follow-Up Study, JAMA, 272, 1439, 10.1001/jama.1994.03520180063036 Block, 1992, Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence, Nutr Cancer, 18, 1, 10.1080/01635589209514201 Gillman, 1995, Protective effect of fruits and vegetables on development of stroke in men, JAMA, 273, 1113, 10.1001/jama.1995.03520380049034 Knekt, 1992, Serum antioxidant vitamins and risk of cataract, BMJ, 305, 1392, 10.1136/bmj.305.6866.1392 Street, 1994, Serum antioxidants and myocardial infarction, Circulation, 90, 1154, 10.1161/01.CIR.90.3.1154 Eicholzer, 1992, Inverse correlation between essential antioxidants in plasma and subsequent risk to develop cancer, ischemic heart disease and stroke respectively: 12-Year follow-up of the Prospective Basel Study, EXS, 62, 398 LeMarchand, 1993, Intake of specific carotenoids and lung cancer risk, Cancer Epidemiol Biomarkers Prev, 2, 183 Stahelin, 1991, Plasma antioxidant vitamins and subsequent cancer mortality in the 12-year follow-up of the prospective Basel Study, Am J Epidemiol, 133, 766, 10.1093/oxfordjournals.aje.a115955 Gey, 1995, Ten-year retrospective on the antioxidant hypothesis of arteriosclerosis: Threshold plasma levels of antioxidant micronutrients related to minimum cardiovascular risk, Nutr Biochem, 6, 206, 10.1016/0955-2863(95)00032-U Niki, 1987, Interaction of ascorbate and alpha tocopherol, Ann New York Acad Sci, 498, 186, 10.1111/j.1749-6632.1987.tb23761.x Palozza, 1992, Beta carotene and alpha tocopherol are synergistic antioxidants, Arch Biochem Biophys, 297, 184, 10.1016/0003-9861(92)90658-J Martenson, 1991, Glutathione deficiency decreases tissue ascorbate levels in newborn rats: Ascorbate spares glutathione and protects, Proc Natl Acad Sci USA, 88, 4656, 10.1073/pnas.88.11.4656 Kostic, 1995, Intestinal absorption, serum clearance, and interactions between lutein and beta carotene when administered to human adults in separate or combined oral doses, Am J Clin Nutr, 62, 604, 10.1093/ajcn/62.3.604 Micozzi, 1992, Plasma carotenoid response to chronic intake of selected foods and beta carotene supplements in men, Am J Clin Nutr, 55, 1120, 10.1093/ajcn/55.6.1120 Khachik, 1995, Lutein, lycopene, and their oxidative metabolites in chemoprevention of cancer, J Cell Biochem, 22, 236, 10.1002/jcb.240590830 Greenberg, 1994, A clinical trial of antioxidant vitamins to prevent colorectal adenoma, NEJM, 331, 141, 10.1056/NEJM199407213310301 Roncucci, 1993, Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas, Dis Colon Rectum, 36, 227, 10.1007/BF02053502 1996, Nonprescription pharmaceuticals and nutritionals, The Tan Sheet, 4, 4 1994, The effect of vitamins E and beta carotene on the incidence of lung cancer and other cancers in male smokers, NEJM, 330, 1029, 10.1056/NEJM199404143301501 Gazaino, 1990, Beta carotene therapy for chronic stable angina, Circulation, 82, 201 Zhang, 1991, Carotenoids enhance gap junctional communication and inhibit lipid peroxidation in C3H/10T1/2 cells: Relationship to their cancer chemopreventive action, Carcinogenesis, 12, 2109, 10.1093/carcin/12.11.2109 Murakoshi, 1992, Potent preventive action of alpha carotene against carcinogenesis: Spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha carotene than by beta carotene, Cancer Res, 52, 6583 Giovannucci, 1995, Intake of carotenoids and retinol in relation to risk of prostate cancer, J Natl Cancer Inst, 87, 1767, 10.1093/jnci/87.23.1767 Franceschi, 1994, Tomatoes and risk of digestive-tract cancers, Int J Cancer, 59, 181, 10.1002/ijc.2910590207 Gerster, 1993, Anticarcinogenic effect of common carotenoids, Int J Vitamin Nutr Res, 63, 93 Seddon, 1994, Dietary carotenoids, vitamins A, C, and E and advanced age-related macular degeneration, JAMA, 272, 1413, 10.1001/jama.1994.03520180037032 Batieha, 1993, Serum micronutrients and the subsequent risk of cervical cancer in a population based nested case control study, Cancer Epidemiol, Biomarkers Prev, 2, 335 Snodderly, 1995, Evidence for protection against age-related macular degeneration by carotenoids and antioxidants vitamins, Am J Clin Nutr, 62, 1448S, 10.1093/ajcn/62.6.1448S Schlach, 1992, Carotenoids in the retina: A review of their possible role in preventing or limiting damage caused by light and oxygen, 280 Yeum, 1995, Measurement of carotenoids, retinoids, and tocopherols in human lenses, Invest Ophthalmol Vis Sci, 36, 2756 Ribaya-Mercado, 1995, Skin lycopene is destroyed preferentially over beta carotene during ultraviolet irradiation in humans, J Nutr, 125, 1854, 10.1093/jn/125.7.1854 Bui, 1994, Simple determination of retinol, alpha tocopherol and carotenoids (lutein, all-trans-lycopene, alpha and beta carotenes) in human plasma by isocratic liquid chromatography, J Chromatogr B Biomed Appl, B654, 129, 10.1016/0378-4347(93)E0441-R Khachik, 1992, Separation and quantification of carotenoids in foods, 213A, 347 Tateishi, 1987, Serum lipid peroxide assayed by a new colorimetric method, Exp Gerontol, 22, 103, 10.1016/0531-5565(87)90045-3 Wade, 1988, Plasma thiobarbituric acid reactivity: Reaction conditions and the role of iron, antioxidants and lipid peroxy radicals on the quantitation of plasma lipid peroxides, Life Sci, 43, 1085, 10.1016/0024-3205(88)90204-4 Cavina, 1988, Carotenoids, retinoids, and alpha-tocopherol in human serum: Identification and determination by reversed-phase HPLC, J Pharm Biomed Anal, 6, 259, 10.1016/0731-7085(88)80052-9 Stryker, 1988, The relation of diet, cigarette smoking, and alcohol consumption to plasma beta carotene and alpha tocopherol levels, Am J Epidemiol, 127, 283, 10.1093/oxfordjournals.aje.a114804 Stahl, 1992, Cis-trans isomers and lycopene and beta carotene in human serum and tissues, Arch Biochem Biophys, 294, 173, 10.1016/0003-9861(92)90153-N Menkes, 1986, Serum beta carotene, vitamins A and E, selenium and the risk of lung cancer, NEJM, 315, 1250, 10.1056/NEJM198611133152003 Gey, 1987, Plasma levels of antioxidant vitamins in relation to ischemic heart disease and cancer, Am J Clin Nutr, 45, 1368, 10.1093/ajcn/45.5.1368 Winklhofer-Roob, 1995, Enhanced resistance to oxidation of low density lipoproteins and decreased lipid peroxide formation during beta carotene supplementation in cystic fibrosis, Free Radic Biol Med, 18, 849, 10.1016/0891-5849(94)00203-V Chen, 1994, Protection by vitamins E, selenium, trolox c, ascorbic acid palmitate, acetylcysteine, coenzyme q, beta carotene, canthaxanthin, and (+)-catechin against oxidative damage to liver slices measured by oxidized heme proteins, Free Radic Biol Med, 16, 437, 10.1016/0891-5849(94)90120-1 Nierenberg, 1991, The plasma concentration of beta carotene after chronic oral supplementation, Am J Clin Nutr, 53, 1443, 10.1093/ajcn/53.6.1443 Albanes, 1992, Serum beta carotene before and after beta carotene supplementation, Eur J Clin Nutr, 46, 1061 Prince, 1993, Beta carotene accumulation in serum and skin, Am J Clin Nutr, 57, 175, 10.1093/ajcn/57.2.175 de Pee, 1995, Lack of improvement in vitamin A status with increased consumption of dark-green leafy vegetables, Lancet, 346, 75, 10.1016/S0140-6736(95)92111-7 Sauberlich, 1994, Effects of consumption of an umbelliferous vegetable beverage on constituents in human sera, 258 Kim, 1992, Serum carotenoids and retinol of human subjects consuming carrot juice, Am J Clin Nutr, 55, 1120 Stahl, 1995, All-trans beta carotene preferentially accumulates in human chylomicrons and very low density lipoproteins compared with the 9-cis geometrical isomer, J Nutr, 125, 2128, 10.1093/jn/125.8.2128 Gaziano, 1995, Discrimination in absorption or transport of beta carotene isomers after oral supplementation with either all-trans or 9-cis-beta-carotene, Am J Clin Nutr, 61, 1248, 10.1093/ajcn/61.6.1248 Palozza, 1991, The inhibition of radical-initiated peroxidation of microsomal lipids by both alpha tocopherol and beta carotene, Free Radic Biol Med, 11, 401, 10.1016/0891-5849(91)90158-Y Esterbauer, 1992, The role of lipid peroxidation and antioxidants in oxidation modification of LDL, Free Radic Biol Med, 13, 341, 10.1016/0891-5849(92)90181-F Packer, 1991, Protective role of vitamin E in biological systems, Am J Clin Nutr, 53, 1050S, 10.1093/ajcn/53.4.1050S Abbey, 1993, Antioxidant vitamins and low-density-lipoprotein oxidation, Am J Clin Nutr, 58, 525, 10.1093/ajcn/58.4.525 Meydani, 1994, Beta carotene supplementation increases antioxidants capacity of plasma in older women, J Nutr, 124, 2397, 10.1093/jn/124.12.2397 Ojima, 1993, Consumption of carotenoids in photosensitized oxidation of human plasma low-density lipoprotein, Free Radic Biol Med, 15, 377, 10.1016/0891-5849(93)90037-U Simic, 1994, Inactivation of oxygen radicals by dietary phenolic compounds in anticarcinogenesis, 20 Hara, 1994, Prophylactic functions of tea polyphenols, 34 Fukuzawa, 1993, Location, antioxidant and recycling dynamics of alpha tocopherol in liposome membranes, J Nutr Sci Vitaminol, 39, S9, 10.3177/jnsv.39.Supplement_S9 Esterbauer, 1989, Continuous monitoring of in vitro oxidation of human low density lipoprotein, Free Radic Res Commun, 6, 67, 10.3109/10715768909073429 Murakoshi, 1989, Inhibitory effect of alpha-carotene on proliferation of the human neuroblastoma cell line GOTO, J Natl Cancer Inst, 81, 1649, 10.1093/jnci/81.21.1649 Jacques, 1995, Influence of combined antioxidant nutrient intakes on their plasma concentrations in an elderly population, Am J Clin Nutr, 62, 1228, 10.1093/ajcn/62.6.1228 Hankinson, 1994, All that glitters is not beta carotene, JAMA, 272, 1455, 10.1001/jama.1994.03520180079040