Changes in oxygen consumption induced by fentanyl and thiopentone during balanced anaesthesia
Tóm tắt
Changes in whole body oxygen consumption due to bolus infusions of fentanyl and thiopentone given during ’balanced anaesthesia’ have been examined in 17 patients. It has been shown that fentanyl causes an average decrease in oxygen consumption of 4.9, 8.4, and 5.2per centat 5, 10 and 15 minutes after its infusion. Thiopentone causes an average decrease of 7.0, 8.8, and 1.9 per cent at 5,10 and 15 minutes after infusion. It is believed that the effects of fentanyl and thiopentone on oxygen consumption are caused mainly by decreases in cerebral and myocardial oxygen consumption.
Tài liệu tham khảo
Gump, F.E. Oxygen consumption and caloric expenditure in surgical patients. Surg. Gynecol. Obstet. 137: 499(1973).
Severinghaus, J.W. &Cullen, S.C. Depression of myocardium and body oxygen consumption with fluothane. Anesthesiology25: 627 (1964).
Shackman, R., Graber, G.I., &Redwood, C. Oxygen consumption and anesthesia. Clin. Sci.10: 219(1951).
Theye, R.A. &Tuohy, G.F. Oxygen uptake during light halothane anesthesia in man. Anesthesiology25: 627 (1964).
Nunn, J.F., Bergman, N.A., &Coleman, A.J. Factors influencing the arterial oxygen tension during anesthesia with artificial ventilation. Br. J. Anesth.37: 898(1965).
Nisbet, H.I.A., Dibbinson, T.L.,Thomas, T.A.,et at. Oxygen uptake in ventilated children during methoxylurane anesthesia. Can. Anesth. Soc. J. 20:334(1973).
Nunn, F.F. &Pouliot, J.C. The measurement of gaseous exchange during nitrous oxide anesthesia. Brit. J. Anesth,34: 752 (1962).
Westenskow, D.R.,Johnson, C.C., &Jordan, W.S. Instrumentation for continuous oxygen consumption during anesthesia. Proceedings of the 28th Annual Con. of Eng. in Med. and Biol. p. 476 (1975).
Westenskow, D.R., Johnson, C.C., Jordan, W.S.,et al. Instrumentation for continuous oxygen consumption of critically ill and surgical patients. I.E.E.E. Trans. Biomed. Eng.24: 331–337 (1977).
Theve, R.A. Thiopental and oxygen consumption. Anesth. and Analg.49: 69 (1970).
Wechsler, R.L., Dripps, R.D., &Kety, S.S. Blood flow and oxygen consumption of the human brain during anesthesia produced by thiopental. Anesthesiology12: 308(1951).
Schieve, J.F. &Wilson. W.P. The influence of age, anesthesia and cerebral arteriosclerosis on cerebral vascular activity to CO2. Amer. J. Med.15: 171(1953).
Wade, O.L. &Bishop, J.M. Cardiac output and regional blood flow. Oxford, Blackwell Scientific Publications, p. 268 (1962).
Spurr, G.B., Hutt, B.K., &Horvath, S.M. Responses of dogs to hypothermia. Amer. J. Physiol.179: 139(1954).
Thung, N., Herzog, P., Christlieb I.I.,et al. The cost of respiratory effort in post-operative cardiac patients. Circulation28: 552 (1963).
Wilson, R.S., Sullivan, S.F., Malm, J.R., et al. The oxygen cost of breathing following anesthesia and cardiac surgery. Anesthesiology39: 387 (1973).
Cain, S.M. Increased oxygen uptake with passive hyperventilation of dogs. J. of Appl. Phys.28: 4 (1970).