Challenges of unculturable bacteria: environmental perspectives

Springer Science and Business Media LLC - Tập 19 Số 1 - Trang 1-22 - 2020
Attila Bodor1, Naila Bounedjoum1, György Vincze1, Ágnes Erdeiné Kis1, Krisztián Laczi1, Gábor Bende1, Árpád Szilágyi1, Tamás Kovács2, Katalin Perei1, Gábor Rákhely3
1Department of Biotechnology, University of Szeged, Közép fasor 52., Szeged 6726, Hungary
2Department of Biotechnology, Nanophagetherapy Center, Enviroinvest Corporation, Pecs, Hungary
3Institute of Environmental and Technological Sciences, University of Szeged, Szeged, Hungary

Tóm tắt

AbstractEnvironmental biotechnology offers several promising techniques for the rehabilitation of polluted environments. The modern industrialized world presents novel challenges to the environmental sciences, requiring a constant development and deepening of knowledge to enable the characterization of novel pollutants and a better understanding of the bioremediation strategies as well as their limiting factors. The success of bioremediation depends heavily on the survival and activities of indigenous microbial communities and their interaction with introduced microorganisms. The majority of natural microbiomes remain uncultivated; therefore, further investigations focusing on their intrinsic functions in ecosystems are needed. In this review, we aimed to provide (a) a comprehensive overview of the presence of viable but nonculturable bacteria and yet-to-be-cultivated cells in nature and their diverse awakening strategies in response to, among other factors, signalling extracellular metabolites (autoinducers, resuscitation promoting factors, and siderophores); (b) an outline of the trends in isolating unculturable bacteria; and (c) the potential applications of these hidden players in rehabilitation processes.

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