Cellular targets for transformation by the adenovirus E1A proteins

Cell - Tập 56 - Trang 67-75 - 1989
Peter Whyte1, Nicola M. Williamson1, Ed Harlow1
1Cold Spring Harbor Laboratory Cold Spring Harbor, New York, 11724 USA

Tài liệu tham khảo

Benedict, 1987, Recessive human cancer susceptibility genes (Retinoblastoma and Wilm's loci), Adv. Virol. Oncol., 7, 19 Berk, 1986, Adenovirus promoters and E1A transactivation, Annu. Rev. Genet., 20, 45, 10.1146/annurev.ge.20.120186.000401 Berk, 1978, Structure of the adenovirus 2 early mRNAs, Cell, 14, 695, 10.1016/0092-8674(78)90252-0 Bonner, 1974, A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels, Eur. J. Biochem., 46, 83, 10.1111/j.1432-1033.1974.tb03599.x Borrelli, 1984, Adenovirus 2 E1A products repress enhancer-induced stimulation of transcription, Nature, 312, 608, 10.1038/312608a0 Braithwaite, 1983, Adenovirus-induced alteration of the cell growth cycle: a requirement for expression of E1A but not of E1B, J. Virol., 45, 192, 10.1128/JVI.45.1.192-199.1983 Carlock, 1981, Transformation-defective mutant of adenovirus type 5 containing a single altered E1A mRNA species, J. Virol., 40, 657, 10.1128/JVI.40.3.657-664.1981 DeCaprio, 1988, SV40 large T antigen forms a specific complex with the product of the retinoblastoma susceptibility gene, Cell, 54, 275, 10.1016/0092-8674(88)90559-4 Eliyahu, 1984, Participation of p53 cellular tumour antigen in transformation of normal embryonic cells, Nature, 312, 646, 10.1038/312646a0 Friend, 1987, Deletion of a DNA sequence in retinoblastomas and mesenchymal tumors: organization of the sequence and its encoded protein, 84, 9059 Gallimore, 1974, Viral DNA transformed cells. II. A study of the sequences of adenovirus 2 DNA in nine lines of transformed rat cells using specific fragments of the viral genome, J. Mol. Biol., 89, 49, 10.1016/0022-2836(74)90162-4 Graham, 1974, Size and location of the transforming region in human adenovirus type 5 DNA, Nature, 251, 687, 10.1038/251687a0 Haley, 1984, Transformation properties of type 5 adenovirus mutants that differentially express the E1A gene products, 81, 5734 Hansen, 1985, Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition, Proc. Natl. Acad. Sci. USA, 82, 6216, 10.1073/pnas.82.18.6216 Harbour, 1988, Abnormalities in structure and expression of the human retinoblastoma gene in SCLC, Science, 241, 353, 10.1126/science.2838909 Harlow, 1981, Monoclonal antibodies specific for simian virus 40 tumor antigens, J. Virol., 39, 861, 10.1128/JVI.39.3.861-869.1981 Harlow, 1985, Monoclonal antibodies specific for adenovirus early region 1A proteins: extensive heterogeneity in earlregion 1A products, J. Virol., 55, 533, 10.1128/JVI.55.3.533-546.1985 Harlow, 1986, Association of adenovirus early-region 1A proteins with cellular polypeptides, Mol. Cell. Biol., 6, 1579, 10.1128/MCB.6.5.1579 Hen, 1985, Repression of the immunoglobulin heavy chain enhancer by the adenovirus-2 E1A products, Science, 230, 1391, 10.1126/science.2999984 Houweling, 1980, Partial transformation of primary rat cells by the leftmost 4.5% fragment of adenovirus 5 DNA, Virology, 105, 537, 10.1016/0042-6822(80)90054-9 Jenkins, 1984, Cellular immortalization by a cDNA clone encoding the transformation-associated phosphoprotein p53, Nature, 312, 651, 10.1038/312651a0 Kaczmarek, 1986, Induction of cellular DNA synthesis by purified adenovirus E1A proteins, Virology, 152, 1, 10.1016/0042-6822(86)90366-1 Kalderon, 1984, In vitro mutagenesis of a putative DNA binding domain of SV40 large-T, Virology, 139, 109, 10.1016/0042-6822(84)90334-9 Kimchi, 1988, Absence of TGF-β receptors and growth inhibitory responses in retinoblastoma cells, Science, 240, 196, 10.1126/science.2895499 Kimmelman, 1985, E1A regions of the human adenoviruses and the highly oncogenic simian adenovirus 7 are closely related, J. Virol., 53, 399, 10.1128/JVI.53.2.399-409.1985 Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0 Land, 1983, Tumorigenic conversion of embryo fibroblasts requires at least two cooperating oncogenes, Nature, 304, 596, 10.1038/304596a0 Lee, 1988, Inactivation of the retinoblastoma susceptibility gene in human breast cancers, Science, 241, 218, 10.1126/science.3388033 Lee, 1984, Expression and amplification of the N-myc gene in primary retinoblastoma, Nature, 309, 458, 10.1038/309458a0 Lillie, 1986, An adenovirus E1a protein region required for transformation and transcriptional repression, Cell, 46, 1043, 10.1016/0092-8674(86)90704-X Lillie, 1987, Functional domains of adenovirus type 5 E1A proteins, Cell, 50, 1091, 10.1016/0092-8674(87)90175-9 Montell, 1982, Resolving the functions of overlapping viral genes by site-specific mutagenesis at an mRNA splice site, Nature, 295, 380, 10.1038/295380a0 Moran, 1988, Interactions between cell growth-regulating domains in the products of the adenovirus E1A oncogene, Mol. Cell. Biol., 8, 1756, 10.1128/MCB.8.4.1756 Moran, 1987, Multiple functional domains in the adenovirus E1A gene, Cell, 48, 177, 10.1016/0092-8674(87)90418-1 Moran, 1986, Identification of separate domains in the adenovirus E1A gene for immortalization activity and the activation of virus early genes, Mol. Cell. Biol., 6, 3470, 10.1128/MCB.6.10.3470 Parada, 1984, Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation, Nature, 312, 649, 10.1038/312649a0 Perricaudet, 1979, Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses, Nature, 218, 694, 10.1038/281694a0 Phelps, 1988, The human papillovirus type 16 E7 gene encodes transactivation and transformation functions similar to those of adenovirus E1A, Cell, 53, 539, 10.1016/0092-8674(88)90570-3 Quinlan, 1987, Growth factor(s) produced during infection with adenovirus variant stimulates proliferation of nonestablished epithelial cells, 84, 3283 Quinlan, 1988, Growth factor induction by the adenovirus type 5 E1A 12S protein is required for immortalization of primary epithelial cells, Mol. Cell. Biol., 8, 3191, 10.1128/MCB.8.8.3191 Ruley, 1983, Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture, Nature, 304, 602, 10.1038/304602a0 Schneider, 1987, Mutational analysis of the adenovirus E1A gene: the role of transcriptional regulation in transformation, EMBO J., 6, 2053, 10.1002/j.1460-2075.1987.tb02470.x Schwab, 1985, Human N-myc gene contributes to nepplastic transformation of mammalian cell in culture, Nature, 316, 160, 10.1038/316160a0 Squire, 1986, Tumour induction by the retinoblastoma mutation is independent of N-myc expression, Nature, 322, 555, 10.1038/322555a0 Stabel, 1985, The release of growth arrest by microinjection of adenovirus E1A DNA, EMBO J., 4, 2329, 10.1002/j.1460-2075.1985.tb03934.x Subramanian, 1988, An N-terminal region of adenovirus E1A essential for cell transformation and induction of an epithelial growth factor, Oncogene, 2, 105 van den Elsen, 1983, Expression of region E1B of human adenovirus in the absence of region E1A is not sufficient for complete transformation, Virology, 128, 377, 10.1016/0042-6822(83)90264-7 Velcich, 1985, Adenovirus E1A proteins repress transcription from the SV40 early promoter, Cell, 40, 705, 10.1016/0092-8674(85)90219-3 Velcich, 1988, Adenovirus E1A ras cooperation activity is separate from its positive and negative transcription regulatory functions, Mol. Cell. Biol., 8, 2177, 10.1128/MCB.8.5.2177 Whyte, 1988, Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product, Nature, 334, 124, 10.1038/334124a0 Whyte, 1988, Two regions of the adenovirus early region 1A proteins are required for transformation, J. Virol., 62, 257, 10.1128/JVI.62.1.257-265.1988 Yancopoulos, 1985, N-myc can cooperate with ras to transform normal cells in culture, 82, 5455 Yee, 1985, Detection of cellular proteins associated with human adenovirus type 5 early region 1A polypeptides, Virology, 147, 142, 10.1016/0042-6822(85)90234-X Zerler, 1986, Adenovirus E1A coding sequences that enable ras and pmt oncogenes to transform cultured primary cells, Mol. Cell. Biol., 6, 887, 10.1128/MCB.6.3.887