Cellular molecular and proteomic profiling deciphers the SIRT1 controlled cell death pathways in esophageal adenocarcinoma cells

Cancer Treatment and Research Communications - Tập 26 - Trang 100271 - 2021
Huige Jiang1, Ketki Patil1, Aksal Vashi1, Yuyan Wang1, Emily Strickland1, S. Balakrishna Pai1
1Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA

Tài liệu tham khảo

Martincorena, 2018, Somatic mutant clones colonize the human esophagus with age, Science, 362, 911, 10.1126/science.aau3879 Parkin, 2001, Estimating the world cancer burden: globocan 2000, Int. J. Cancer, 94, 153, 10.1002/ijc.1440 www.cancer.org/cancer/esophagus-cancer/about/key-statistics.html. Koshy, 2004, Multiple management modalities in esophageal cancer: epidemiology, presentation and progression, work-up, and surgical approaches, Oncologist, 9, 137, 10.1634/theoncologist.9-2-137 Vaughan, 2015, Precision prevention of oesophageal adenocarcinoma, Nat. Rev. Gastroenterol. Hepatol., 12, 243, 10.1038/nrgastro.2015.24 Kuwano, 1996, Oesophageal cancer composed of mixed histological types, Eur. J. Surg. Oncol., 22, 225, 10.1016/S0748-7983(96)80007-2 Carafa, 2019, Dual tumor suppressor and tumor promoter action of sirtuins in determining malignant phenotype, Front. Pharmacol., 10, 38, 10.3389/fphar.2019.00038 Zhang, 2010, SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions, Biochim. Biophys. Acta, 1804, 1666, 10.1016/j.bbapap.2009.10.022 Deng, 2009, SIRT1, is it a tumor promoter or tumor suppressor?, Int. J. Biol. Sci., 5, 147, 10.7150/ijbs.5.147 Calvanese, 2010, Sirtuin 1 regulation of developmental genes during differentiation of stem cells, Proc. Natl. Acad. Sci. USA, 107, 13736, 10.1073/pnas.1001399107 Kojima, 2008, A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells, Biochem. Biophys. Res. Commun., 373, 423, 10.1016/j.bbrc.2008.06.045 Lin, 2013, The roles of SIRT1 in cancer, Genes Cancer, 4, 97, 10.1177/1947601912475079 Vaziri, 2001, hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase, Cell, 107, 149, 10.1016/S0092-8674(01)00527-X Kozako, 2014, Anticancer agents targeted to sirtuins, Molecules, 19, 20295, 10.3390/molecules191220295 Grozinger, 2001, Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening, J. Biol. Chem., 276, 38837, 10.1074/jbc.M106779200 Fong, 2014, The antiproliferative and apoptotic effects of sirtinol, a sirtuin inhibitor on human lung cancer cells by modulating Akt/beta-catenin-Foxo3a axis, ScientificWorldJournal, 2014, 10.1155/2014/937051 Wang, 2012, Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells, Int. J. Oncol., 41, 1101, 10.3892/ijo.2012.1534 Jung-Hynes, 2009, Role of sirtuin histone deacetylase SIRT1 in prostate cancer. A target for prostate cancer management via its inhibition, J. Biol. Chem., 284, 3823, 10.1074/jbc.M807869200 Eales, 2016, Hypoxia and metabolic adaptation of cancer cells, Oncogenesis, 5, e190, 10.1038/oncsis.2015.50 Strese, 2013, Effects of hypoxia on human cancer cell line chemosensitivity, BMC Cancer, 13, 331, 10.1186/1471-2407-13-331 Lodise, 2019, Inhibition of prostate cancer cells by 4,5-Dicaffeoylquinic acid through cell cycle arrest, Prostate Cancer, 2019, 10.1155/2019/4520645 Tonge, 2001, Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology, Proteomics, 1, 377, 10.1002/1615-9861(200103)1:3<377::AID-PROT377>3.0.CO;2-6 Qu, 2018, Small molecule promotes beta-catenin citrullination and inhibits Wnt signaling in cancer, Nat. Chem. Biol., 14, 94, 10.1038/nchembio.2510 Roth, 2014, Sorting out functions of sirtuins in cancer, Oncogene, 33, 1609, 10.1038/onc.2013.120 Yuan, 2013, The emerging and diverse roles of sirtuins in cancer: a clinical perspective, Onco. Targets Ther., 6, 1399 Lee, 2018, A facile in vitro platform to study cancer cell dormancy under hypoxic microenvironments using CoCl2, J. Biol. Eng., 12, 12, 10.1186/s13036-018-0106-7 Majeski, 2004, Mechanisms of chaperone-mediated autophagy, Int. J. Biochem. Cell. Biol., 36, 2435, 10.1016/j.biocel.2004.02.013 Moghanibashi, 2013, Esophageal cancer alters the expression of nuclear pore complex binding protein Hsc70 and eIF5A-1, Funct. Integr. Genomics., 13, 253, 10.1007/s10142-013-0320-9 Zhu, 2017, eEF2K promotes progression and radioresistance of esophageal squamous cell carcinoma, Radiother. Oncol., 124, 439, 10.1016/j.radonc.2017.04.001 Shi, 2018, Eukaryotic elongation factors 2 promotes tumor cell proliferation and correlates with poor prognosis in ovarian cancer, Tissue Cell, 53, 53, 10.1016/j.tice.2018.05.014 Ladner, 2000, dUTP nucleotidohydrolase isoform expression in normal and neoplastic tissues: association with survival and response to 5-fluorouracil in colorectal cancer, Cancer Res., 60, 3493 Mol, 1996, Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits, Structure, 4, 1077, 10.1016/S0969-2126(96)00114-1 Stoimenov, 2009, PCNA on the crossroad of cancer, Biochem. Soc. Trans., 37, 605, 10.1042/BST0370605 Wang, 2014, PCNA: a silent housekeeper or a potential therapeutic target?, Trends Pharmacol. Sci., 35, 178, 10.1016/j.tips.2014.02.004 Kimos, 2004, Esophagin and proliferating cell nuclear antigen (PCNA) are biomarkers of human esophageal neoplastic progression, Int. J. Cancer, 111, 415, 10.1002/ijc.20267 Yang, 2007, Inhibitors of ubiquitin-activating enzyme (E1), a new class of potential cancer therapeutics, Cancer Res., 67, 9472, 10.1158/0008-5472.CAN-07-0568 Peters, 1993, Glutathione S-transferases in esophageal cancer, Carcinogenesis, 14, 1377, 10.1093/carcin/14.7.1377 Townsend, 2003, The role of glutathione-S-transferase in anti-cancer drug resistance, Oncogene, 22, 7369, 10.1038/sj.onc.1206940 Turella, 2005, Proapoptotic activity of new glutathione S-transferase inhibitors, Cancer Res., 65, 3751, 10.1158/0008-5472.CAN-04-3903 Kusumawidjaja, 2007, Basic transcription factor 3 (BTF3) regulates transcription of tumor-associated genes in pancreatic cancer cells, Cancer Biol. Ther., 6, 367, 10.4161/cbt.6.3.3704 Li, 2019, Basic transcription factor 3 expression silencing attenuates colon cancer cell proliferation and migration in vitro, Oncol. Lett., 17, 113 Artero-Castro, 2011, Expression of the ribosomal proteins Rplp0, Rplp1, and Rplp2 in gynecologic tumors, Hum. Pathol., 42, 194, 10.1016/j.humpath.2010.04.020 Chen, 2007, Proteomic analysis of EZH2 downstream target proteins in hepatocellular carcinoma, Proteomics, 7, 3097, 10.1002/pmic.200700019 Endoh, 2004, Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro, Mol. Cell. Biol., 24, 3324, 10.1128/MCB.24.8.3324-3336.2004 Li, 2007, Human SSRP1 has Spt16-dependent and -independent roles in gene transcription, J. Biol. Chem., 282, 6936, 10.1074/jbc.M603822200 Ding, 2002, A misspliced form of the cholecystokinin-B/gastrin receptor in pancreatic carcinoma: role of reduced sellular U2AF35 and a suboptimal 3′-splicing site leading to retention of the fourth intron, Cancer Res., 62, 947 Bu, 2011, Role for transcription factor TFII-I in the suppression of SSeCKS/Gravin/Akap12 transcription by Src, Int. J. Cancer, 128, 1836, 10.1002/ijc.25524 Stasyk, 2005, Phosphoproteome profiling of transforming growth factor (TGF)-beta signaling: abrogation of TGFbeta1-dependent phosphorylation of transcription factor-II-I (TFII-I) enhances cooperation of TFII-I and Smad3 in transcription, Mol. Biol. Cell., 16, 4765, 10.1091/mbc.e05-03-0257 Hakimi, 2003, A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes, J. Biol. Chem., 278, 7234, 10.1074/jbc.M208992200 Heath-Engel, 2008, The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family, Oncogene, 27, 6419, 10.1038/onc.2008.309 Kawano, 2000, Identification of a new endoplasmic reticulum-resident protein recognized by HLA-A24-restricted tumor-infiltrating lymphocytes of lung cancer, Cancer Res., 60, 3550 Stengel, 2011, Cdc42 in oncogenic transformation, invasion, and tumorigenesis, Cell Signal, 23, 1415, 10.1016/j.cellsig.2011.04.001 Zins, 2013, Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity, J. Transl. Med., 11, 295, 10.1186/1479-5876-11-295 Eckschlager, 2017, Histone deacetylase inhibitors as anticancer drugs, Int. J. Mol. Sci., 18, 10.3390/ijms18071414 Groh, 2015, The synergistic effects of DNA-damaging drugs cisplatin and etoposide with a histone deacetylase inhibitor valproate in high-risk neuroblastoma cells, Int. J. Oncol., 47, 343, 10.3892/ijo.2015.2996