Cellular functions of TIP60

Akhtar, 2000, Chromodomains are protein–RNA interaction modules, Nature, 407, 405, 10.1038/35030169

Awasthi, 2005, A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactions, Mol. Cell. Biol., 25, 6178, 10.1128/MCB.25.14.6178-6198.2005

Baek, 2002, Exchange of N-CoR corepressor and TIP60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein, Cell, 110, 55, 10.1016/S0092-8674(02)00809-7

Barron, 2005, Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes, J. Biol. Chem., 280, 11816, 10.1074/jbc.M412408200

Berns, 2004, A large-scale RNAi screen in human cells identifies new components of the p53 pathway, Nature, 428, 431, 10.1038/nature02371

Bird, 2002, Acetylation of histone H4 by Esa1 is required for DNA double-strand break repair, Nature, 419, 411, 10.1038/nature01035

Brady, 1999, TIP60 is a nuclear hormone receptor coactivator, J. Biol. Chem., 274, 17599, 10.1074/jbc.274.25.17599

Cai, 2005, The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes, J. Biol. Chem., 280, 13665, 10.1074/jbc.M500001200

Cai, 2003, Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex, J. Biol. Chem., 278, 42733, 10.1074/jbc.C300389200

Cao, 2001, A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase TIP60, Science, 293, 115, 10.1126/science.1058783

Cao, 2004, Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation, J. Biol. Chem., 279, 24601, 10.1074/jbc.M402248200

Carrozza, 2003, The diverse functions of histone acetyltransferase complexes, Trends Genet., 19, 321, 10.1016/S0168-9525(03)00115-X

Ceol, 2004, A new class of C. elegans synMuv genes implicates a TIP60/NuA4-like HAT complex as a negative regulator of Ras signaling, Dev. Cell, 6, 563, 10.1016/S1534-5807(04)00065-6

Clarke, 1999, Esa1p is an essential histone acetyltransferase required for cell cycle progression, Mol. Cell. Biol., 19, 2515, 10.1128/MCB.19.4.2515

Col, 2005, HIV-1 Tat targets TIP60 to impair the apoptotic cell response to genotoxic stresses, EMBO J., 24, 2634, 10.1038/sj.emboj.7600734

Creaven, 1999, Control of the histone-acetyltransferase activity of TIP60 by the HIV-1 transactivator protein, Tat, Biochemistry, 38, 8826, 10.1021/bi9907274

Dechend, 1999, The Bcl-3 oncoprotein acts as a bridging factor between NF-kappaB/Rel and nuclear co-regulators, Oncogene, 18, 3316, 10.1038/sj.onc.1202717

Downs, 2004, Binding of chromatin-modifying activities to phosphorylated histone H2A at DNA damage sites, Mol. Cell., 16, 979, 10.1016/j.molcel.2004.12.003

Doyon, 2004, The highly conserved and multifunctional NuA4 HAT complex, Curr. Opin. Genet. Dev., 14, 147, 10.1016/j.gde.2004.02.009

Doyon, 2004, Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans, Mol. Cell. Biol., 24, 1884, 10.1128/MCB.24.5.1884-1896.2004

Feldman, 2001, The development of androgen-independent prostate cancer, Nat. Rev. Cancer, 1, 34, 10.1038/35094009

Frank, 2003, MYC recruits the TIP60 histone acetyltransferase complex to chromatin, EMBO Rep., 4, 575, 10.1038/sj.embor.embor861

Gaughan, 2001, TIP60 is a co-activator specific for class I nuclear hormone receptors, J. Biol. Chem., 276, 46841, 10.1074/jbc.M103710200

Gaughan, 2002, TIP60 and histone deacetylase 1 regulate androgen receptor activity through changes to the acetylation status of the receptor, J. Biol. Chem., 277, 25904, 10.1074/jbc.M203423200

Gavaravarapu, 2000, TIP60 inhibits activation of CREB protein by protein kinase A, Biochem. Biophys. Res. Commun., 269, 758, 10.1006/bbrc.2000.2358

Gupta, 2005, Involvement of human MOF in ATM function, Mol. Cell. Biol., 25, 5292, 10.1128/MCB.25.12.5292-5305.2005

Halkidou, 2003, Expression of TIP60, an androgen receptor coactivator, and its role in prostate cancer development, Oncogene, 22, 2466, 10.1038/sj.onc.1206342

Halkidou, 2004, Putative involvement of the histone acetyltransferase TIP60 in ribosomal gene transcription, Nucleic Acids Res., 32, 1654, 10.1093/nar/gkh296

Hlubek, 2001, TIP60 is a cell-type-specific transcriptional regulator, J. Biochem. (Tokyo), 129, 635, 10.1093/oxfordjournals.jbchem.a002901

Ikura, 2000, Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis, Cell, 102, 463, 10.1016/S0092-8674(00)00051-9

Jazayeri, 2004, Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair, Proc. Natl. Acad. Sci. U.S.A., 101, 1644, 10.1073/pnas.0304797101

Kamine, 1996, Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator, Virology, 216, 357, 10.1006/viro.1996.0071

Kim, 2005, Transcriptional regulation of a metastasis suppressor gene by TIP60 and beta-catenin complexes, Nature, 434, 921, 10.1038/nature03452

Kim, 2004, Inhibition of histone deacetylation enhances the neurotoxicity induced by the C-terminal fragments of amyloid precursor protein, J. Neurosci. Res., 75, 117, 10.1002/jnr.10845

Kimura, 1998, TIP60 acetylates six lysines of a specific class in core histones in vitro, Genes Cells, 3, 789, 10.1046/j.1365-2443.1998.00229.x

Kinoshita, 2003, The intracellular domain of the low density lipoprotein receptor-related protein modulates transactivation mediated by amyloid precursor protein and Fe65, J. Biol. Chem., 278, 41182, 10.1074/jbc.M306403200

Kinoshita, 2002, The gamma secretase-generated carboxyl-terminal domain of the amyloid precursor protein induces apoptosis via TIP60 in H4 cells, J. Biol. Chem., 277, 28530, 10.1074/jbc.M203372200

Kobor, 2004, A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin, PLoS Biol., 2, E131, 10.1371/journal.pbio.0020131

Kramps, 2004, E2F and Sp1/Sp3 Synergize but are not sufficient to activate the MYCN gene in neuroblastomas, J. Biol. Chem., 279, 5110, 10.1074/jbc.M304758200

Kusch, 2004, Acetylation by TIP60 is required for selective histone variant exchange at DNA lesions, Science, 306, 2084, 10.1126/science.1103455

Lang, 2003, The adenovirus E1A oncoprotein recruits the cellular TRRAP/GCN5 histone acetyltransferase complex, Oncogene, 22, 2836, 10.1038/sj.onc.1206376

Lee, 2001, TIP60 and HDAC7 interact with the endothelin receptor a and may be involved in downstream signaling, J. Biol. Chem., 276, 16597, 10.1074/jbc.C000909200

Legube, 2002, TIP60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation, EMBO J., 21, 1704, 10.1093/emboj/21.7.1704

Legube, 2004, Role of the histone acetyl transferase TIP60 in the p53 pathway, J. Biol. Chem., 279, 44825, 10.1074/jbc.M407478200

Legube, 2003, Identification of a larger form of the histone acetyl transferase TIP60, Gene, 310, 161, 10.1016/S0378-1119(03)00547-X

Lemercier, 2003, TIP60 acetyltransferase activity is controlled by phosphorylation, J. Biol. Chem., 278, 4713, 10.1074/jbc.M211811200

Leng, 2003, Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation, Cell, 112, 779, 10.1016/S0092-8674(03)00193-4

Li, 2004, HAT cofactor Trrap regulates the mitotic checkpoint by modulation of Mad1 and Mad2 expression, EMBO J., 23, 4824, 10.1038/sj.emboj.7600479

Li, 2004, Cleavage of amyloid-beta precursor protein and amyloid-beta precursor-like protein by BACE 1, J. Biol. Chem., 279, 10542, 10.1074/jbc.M310001200

Logan, 2004, Control of human PIRH2 protein stability: Involvement of TIP60 and the proteosome, J. Biol. Chem., 279, 11696, 10.1074/jbc.M312712200

Lough, 2002, Transient expression of TIP60 protein during early chick heart development, Dev. Dyn., 223, 419, 10.1002/dvdy.10058

McAllister, 2002, Characterization and expression of the mouse tat interactive protein 60kD (TIP60) gene, Gene, 289, 169, 10.1016/S0378-1119(02)00546-2

Mizuguchi, 2004, ATP-driven exchange of histone H2AZ variant catalyzed by SWR1 chromatin remodeling complex, Science, 303, 343, 10.1126/science.1090701

Murr, 2006, Histone acetylation by Trrap-TIP60 modulates loading of repair proteins and repair of DNA double-strand breaks, Nat. Cell. Biol., 8, 91, 10.1038/ncb1343

Nordentoft, 2003, The acetyltransferase 60kDa trans-acting regulatory protein of HIV type 1-interacting protein (TIP60) interacts with the translocation E26 transforming-specific leukaemia gene (TEL) and functions as a transcriptional co-repressor, Biochem. J., 374, 165, 10.1042/bj20030087

Nourani, 2001, Role of an ING1 growth regulator in transcriptional activation and targeted histone acetylation by the NuA4 complex, Mol. Cell. Biol., 21, 7629, 10.1128/MCB.21.22.7629-7640.2001

Panchenko, 2004, von Hippel-Lindau partner Jade-1 is a transcriptional co-activator associated with histone acetyltransferase activity, J. Biol. Chem., 279, 56032, 10.1074/jbc.M410487200

Patel, 2004, The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60, Mol. Cell. Biol., 24, 10826, 10.1128/MCB.24.24.10826-10834.2004

Polevoda, B., & Sherman, F. (2002). The diversity of acetylated proteins. Genome Biol., 3 [reviews].

Ran, 2000, Identification of an alternatively spliced form of the Tat interactive protein (TIP60), TIP60(beta), Gene, 258, 141, 10.1016/S0378-1119(00)00410-8

Sharma, 2000, Androgen receptor interacts with a novel MYST protein, HBO1, J. Biol. Chem., 275, 35200, 10.1074/jbc.M004838200

Sheridan, 2001, PLIP, a novel splice variant of TIP60, interacts with group IV cytosolic phospholipase A(2), induces apoptosis, and potentiates prostaglandin production, Mol. Cell. Biol., 21, 4470, 10.1128/MCB.21.14.4470-4481.2001

Sliva, 1999, TIP60 interacts with human interleukin-9 receptor alpha-chain, Biochem. Biophys. Res. Commun., 263, 149, 10.1006/bbrc.1999.1083

Strahl, 2000, The language of covalent histone modifications, Nature, 403, 41, 10.1038/47412

Sumioka, 2005, Role of 14-3-3gamma in FE65-dependent gene transactivation mediated by the amyloid beta-protein precursor cytoplasmic fragment, J. Biol. Chem., 280, 42364, 10.1074/jbc.M504278200

Sun, 2005, A role for the TIP60 histone acetyltransferase in the acetylation and activation of ATM, Proc. Natl. Acad. Sci. U.S.A., 102, 13182, 10.1073/pnas.0504211102

Tamburini, 2005, Localized histone acetylation and deacetylation triggered by the homologous recombination pathway of double-strand DNA repair, Mol. Cell. Biol., 25, 4903, 10.1128/MCB.25.12.4903-4913.2005

Taubert, 2004, E2F-dependent histone acetylation and recruitment of the TIP60 acetyltransferase complex to chromatin in late G1, Mol. Cell. Biol., 24, 4546, 10.1128/MCB.24.10.4546-4556.2004

Telese, 2005, Transcription regulation by the adaptor protein Fe65 and the nucleosome assembly factor SET, EMBO Rep., 6, 77, 10.1038/sj.embor.7400309

Turner, 2002, Cellular memory and the histone code, Cell, 111, 285, 10.1016/S0092-8674(02)01080-2

Utley, 2003, The MYST family of histone acetyltransferases, Curr. Top. Microbiol. Immunol., 274, 203

Utley, 2005, Regulation of NuA4 histone acetyltransferase activity in transcription and DNA repair by phosphorylation of histone H4, Mol. Cell. Biol., 25, 8179, 10.1128/MCB.25.18.8179-8190.2005

von Rotz, 2004, The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor, J. Cell. Sci., 117, 4435, 10.1242/jcs.01323

Xiao, 2003, TIP60 is a co-repressor for STAT3, J. Biol. Chem., 278, 11197, 10.1074/jbc.M210816200

Yamamoto, 1997, Novel substrate specificity of the histone acetyltransferase activity of HIV-1-Tat interactive protein TIP60, J. Biol. Chem., 272, 30595, 10.1074/jbc.272.49.30595

Yan, 2000, Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases, Mol. Cell., 6, 1195, 10.1016/S1097-2765(00)00116-7

Yan, 2002, The catalytic mechanism of the ESA1 histone acetyltransferase involves a self-acetylated intermediate, Nat. Struct. Biol., 9, 862

Yang, Z., Cool, B., Martin, G., & Hu, Q. (2006). A dominant role for FE65 (APBB1) in nuclear signaling. J. Biol. Chem. [Epub ahead of print].