Cell Biology of the Mitochondrion

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Caito, 2012, Genome-wide analyses of metal responsive genes in Caenorhabditis elegans., Front. Genet., 3, 52, 10.3389/fgene.2012.00052

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Chen, 2003, Production of reactive oxygen species by mitochondria: central role of complex III., J. Biol. Chem., 278, 36027, 10.1074/jbc.M304854200

Chen, 2011, Quality improvement of mitochondrial respiratory chain complex enzyme assays using Caenorhabditis elegans., Genet. Med., 13, 794, 10.1097/GIM.0b013e31821afca5

Clark, 1997, A dynamin GTPase mutation causes a rapid and reversible temperature-inducible locomotion defect in C. elegans., Proc. Natl. Acad. Sci. USA, 94, 10438, 10.1073/pnas.94.19.10438

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Dancy, 2015, Mitochondrial bioenergetics and disease in Caenorhabditis elegans., Front. Biosci. (Landmark Ed.), 20, 198, 10.2741/4305

Dancy, 2016, Glutathione S-transferase mediates an ageing response to mitochondrial dysfunction., Mech. Ageing Dev., 153, 14, 10.1016/j.mad.2015.12.001

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Deng, 2016, The mitokine quest(ion)., Cell Res., 26, 1265, 10.1038/cr.2016.138

Desjardins, 2017, Antioxidants reveal an inverted U-shaped dose-response relationship between reactive oxygen species levels and the rate of aging in Caenorhabditis elegans., Aging Cell, 16, 104, 10.1111/acel.12528

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Djeddi, 2015, Sperm-inherited organelle clearance in C. elegans relies on LC3-dependent autophagosome targeting to the pericentrosomal area., Development, 142, 1705, 10.1242/dev.117879

Durieux, 2011, The cell-non-autonomous nature of electron transport chain-mediated longevity., Cell, 144, 79, 10.1016/j.cell.2010.12.016

Egan, 2011, Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy., Science, 331, 456, 10.1126/science.1196371

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Falk, 2006, Mitochondrial complex I function modulates volatile anesthetic sensitivity in C. elegans., Curr. Biol., 16, 1641, 10.1016/j.cub.2006.06.072

Falk, 2008, Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans., Mol. Genet. Metab., 93, 388, 10.1016/j.ymgme.2007.11.007

Fang, 2017, Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway., Sci. Rep., 7, 46208, 10.1038/srep46208

Felkai, 1999, CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans., EMBO J., 18, 1783, 10.1093/emboj/18.7.1783

Feng, 2001, Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans., Dev. Cell, 1, 633, 10.1016/S1534-5807(01)00071-5

Fiorese, 2017, Integrating the UPRmt into the mitochondrial maintenance network., Crit. Rev. Biochem. Mol. Biol., 52, 304, 10.1080/10409238.2017.1291577

Fong, 2016, Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer disease model., Sci. Rep., 6, 33781, 10.1038/srep33781

Frey, 2002, Insight into mitochondrial structure and function from electron tomography., Biochim. Biophys. Acta, 1555, 196, 10.1016/S0005-2728(02)00278-5

Friedman, 2014, Mitochondrial form and function., Nature, 505, 335, 10.1038/nature12985

Ghose, 2013, Anoxia-reoxygenation regulates mitochondrial dynamics through the hypoxia response pathway, SKN-1/Nrf, and stomatin-like protein STL-1/SLP-2., PLoS Genet., 9, e1004063, 10.1371/journal.pgen.1004063

Gitschlag, 2016, Homeostatic responses regulate selfish mitochondrial genome dynamics in C. elegans., Cell Metab., 24, 91, 10.1016/j.cmet.2016.06.008

Gonzalez-Cabo, 2010, Flavin adenine dinucleotide rescues the phenotype of frataxin deficiency., PLoS One, 5, e8872, 10.1371/journal.pone.0008872

Gonzalez-Hunt, 2014, Exposure to mitochondrial genotoxins and dopaminergic neurodegeneration in Caenorhabditis elegans., PLoS One, 9, e114459, 10.1371/journal.pone.0114459

Grad, 2004, Mitochondrial complex I mutations in Caenorhabditis elegans produce cytochrome c oxidase deficiency, oxidative stress and vitamin-responsive lactic acidosis., Hum. Mol. Genet., 13, 303, 10.1093/hmg/ddh027

Grad, 2006, Riboflavin enhances the assembly of mitochondrial cytochrome c oxidase in C. elegans NADH-ubiquinone oxidoreductase mutants., Biochim. Biophys. Acta, 1757, 115, 10.1016/j.bbabio.2005.11.009

Grad, 2005, Introduction of an additional pathway for lactate oxidation in the treatment of lactic acidosis and mitochondrial dysfunction in Caenorhabditis elegans., Proc. Natl. Acad. Sci. USA, 102, 18367, 10.1073/pnas.0506939102

Guo, 2003, The ubiquinone-binding site of the Saccharomyces cerevisiae succinate-ubiquinone oxidoreductase is a source of superoxide., J. Biol. Chem., 278, 47629, 10.1074/jbc.M306312200

Hahn, 2016, Structure of a complete ATP synthase dimer reveals the molecular basis of inner mitochondrial membrane morphology., Mol. Cell, 63, 445, 10.1016/j.molcel.2016.05.037

Han, 2016, Mitochondria localize to injured axons to support regeneration., Neuron, 92, 1308, 10.1016/j.neuron.2016.11.025

Harbauer, 2014, The protein import machinery of mitochondria-a regulatory hub in metabolism, stress, and disease., Cell Metab., 19, 357, 10.1016/j.cmet.2014.01.010

Hartman, 2001, Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans., Mech. Ageing Dev., 122, 1187, 10.1016/S0047-6374(01)00259-7

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Haynes, 2010, The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans., Mol. Cell, 37, 529, 10.1016/j.molcel.2010.01.015

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Hekimi, 2016, Mitochondrial ROS and the effectors of the intrinsic apoptotic pathway in aging cells: the discerning killers!., Front. Genet., 7, 161, 10.3389/fgene.2016.00161

Herlan, 2004, Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor., J. Cell Biol., 165, 167, 10.1083/jcb.200403022

Hoogenraad, 2017, A brief history of the discovery of the mitochondrial unfolded protein response in mammalian cells., J. Bioenerg. Biomembr., 10.1007/s10863-017-9703-2

Hsieh, 2016, Functional impairment in miro degradation and mitophagy is a shared feature in familial and sporadic Parkinson’s disease., Cell Stem Cell, 19, 709, 10.1016/j.stem.2016.08.002

Huang, 2011, piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling., Dev. Cell, 20, 376, 10.1016/j.devcel.2011.01.004

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Ijomone, 2016, Null allele mutants of trt-1, the catalytic subunit of telomerase in Caenorhabditis elegans, are less sensitive to Mn-induced toxicity and DAergic degeneration., Neurotoxicology, 57, 54, 10.1016/j.neuro.2016.08.016

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Jafari, 2015, Tether mutations that restore function and suppress pleiotropic phenotypes of the C. elegans isp-1(qm150) Rieske iron-sulfur protein., Proc. Natl. Acad. Sci. USA, 112, E6148, 10.1073/pnas.1509416112

Jafari, 2016, New functional and biophysical insights into the mitochondrial Rieske iron-sulfur protein from genetic suppressor analysis in C. elegans., Worm, 5, e1174803, 10.1080/21624054.2016.1174803

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Kamal, 2016, Loss of hif-1 promotes resistance to the exogenous mitochondrial stressor ethidium bromide in Caenorhabditis elegans., BMC Cell Biol., 17, 34, 10.1186/s12860-016-0112-x

Kamp, 2010, Inhibition of mitochondrial fusion by alpha-synuclein is rescued by PINK1, Parkin and DJ-1., EMBO J., 29, 3571, 10.1038/emboj.2010.223

Kanazawa, 2008, The C. elegans Opa1 homologue EAT-3 is essential for resistance to free radicals., PLoS Genet., 4, e1000022, 10.1371/journal.pgen.1000022

Kaufman, 2015, Mitochondrial proteostatic collapse leads to hypoxic injury., Curr. Biol., 25, 2171, 10.1016/j.cub.2015.06.062

Kayser, 1999, GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in the nematode Caenorhabditis elegans., Anesthesiology, 90, 545, 10.1097/00000542-199902000-00031

Kayser, 2001, Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans., J. Biol. Chem., 276, 20551, 10.1074/jbc.M011066200

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