Celastrol induces ferroptosis in activated HSCs to ameliorate hepatic fibrosis via targeting peroxiredoxins and HO-1
Tài liệu tham khảo
Lim, 2008, The global impact of hepatic fibrosis and end-stage liver disease, Clin Liver Dis, 12, 733, 10.1016/j.cld.2008.07.007
Xu, 2012, Liver fibrosis: mechanisms of immune-mediated liver injury, Cell Mol Immunol, 9, 296, 10.1038/cmi.2011.53
Ellis, 2012, Clinical evidence for the regression of liver fibrosis, J Hepatol, 56, 1171, 10.1016/j.jhep.2011.09.024
Bataller, 2005, Liver fibrosis, J Clin Invest, 115, 209, 10.1172/JCI24282
Trivedi, 2021, The power of plasticity-metabolic regulation of hepatic stellate cells, Cell Metab, 33, 242, 10.1016/j.cmet.2020.10.026
Friedman, 2004, Mechanisms of disease: mechanisms of hepatic fibrosis and therapeutic implications, Nat Clin Pract Gastroenterol Hepatol, 1, 98, 10.1038/ncpgasthep0055
Jia, 2018, Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells, Redox Biol, 19, 375, 10.1016/j.redox.2018.09.007
Zhang, 2017, Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis, Cell Death Dis, 8, 10.1038/cddis.2017.255
Dixon, 2012, Ferroptosis: an iron-dependent form of nonapoptotic cell death, Cell, 149, 1060, 10.1016/j.cell.2012.03.042
Stockwell, 2017, Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease, Cell, 171, 273, 10.1016/j.cell.2017.09.021
Han, 2020, Ferroptosis and its potential role in human diseases, Front Pharmacol, 11, 239, 10.3389/fphar.2020.00239
Chen, 2021, Broadening horizons: the role of ferroptosis in cancer, Nat Rev Clin Oncol, 18, 280, 10.1038/s41571-020-00462-0
Sun, 2016, Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis, Hepatology, 64, 488, 10.1002/hep.28574
Li, 2020, Iron regulatory protein 2 is required for artemether-mediated anti-hepatic fibrosis through ferroptosis pathway, Free Radic Biol Med, 160, 845, 10.1016/j.freeradbiomed.2020.09.008
Zhang, 2020, The BRD7–P53–SLC25A28 axis regulates ferroptosis in hepatic stellate cells, Redox Biol, 36, 101619, 10.1016/j.redox.2020.101619
Zhang, 2020, RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells, Autophagy, 16, 1482, 10.1080/15548627.2019.1687985
Tsurusaki, 2019, Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis, Cell Death Dis, 10, 449, 10.1038/s41419-019-1678-y
Zhang, 2018, Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells, Autophagy, 14, 2083, 10.1080/15548627.2018.1503146
Li, 2021, Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma, Acta Pharmacol Sin, 42, 301, 10.1038/s41401-020-0478-3
Kong, 2019, Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway, Biomed Pharmacother, 109, 2043, 10.1016/j.biopha.2018.11.030
Sui, 2018, Magnesium isoglycyrrhizinate ameliorates liver fibrosis and hepatic stellate cell activation by regulating ferroptosis signaling pathway, Biomed Pharmacother, 106, 125, 10.1016/j.biopha.2018.06.060
Kuo, 2020, Chrysophanol attenuates hepatitis B virus X protein-induced hepatic stellate cell fibrosis by regulating endoplasmic reticulum stress and ferroptosis, J Pharmacol Sci, 144, 172, 10.1016/j.jphs.2020.07.014
Hou, 2020, Celastrol: progresses in structure–modifications, structure–activity relationships, pharmacology and toxicology, Eur J Med Chem, 189, 112081, 10.1016/j.ejmech.2020.112081
Xu, 2021, Celastrol in metabolic diseases: progress and application prospects, Pharmacol Res, 167, 105572, 10.1016/j.phrs.2021.105572
Liu, 2015, Treatment of obesity with celastrol, Cell, 161, 999, 10.1016/j.cell.2015.05.011
Corson, 2007, Molecular understanding and modern application of traditional medicines: triumphs and trials, Cell, 130, 769, 10.1016/j.cell.2007.08.021
Zhao, 2019, Celastrol protects from cholestatic liver injury through modulation of SIRT1–FXR signaling, Mol Cell Proteomics, 18, 520, 10.1074/mcp.RA118.000817
Yan, 2021, Celastrol ameliorates propionibacterium acnes/LPS-induced liver damage and MSU-induced gouty arthritis via inhibiting K63 deubiquitination of NLRP3, Phytomedicine, 80, 153398, 10.1016/j.phymed.2020.153398
Zhao, 2020, Celastrol ameliorates acute liver injury through modulation of PPARα, Biochem Pharmacol, 178, 114058, 10.1016/j.bcp.2020.114058
Chang, 2016, Protective effects of celastrol on diethylnitrosamine-induced hepatocellular carcinoma in rats and its mechanisms, Eur J Pharmacol, 784, 173, 10.1016/j.ejphar.2016.04.045
Wang, 2020, Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK–SIRT3 signalling, J Cell Mol Med, 24, 941, 10.1111/jcmm.14805
Seki, 2009, CCR2 promotes hepatic fibrosis in mice, Hepatology, 50, 185, 10.1002/hep.22952
Liu, 2021, Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion, J Neuroinflammation, 18, 174, 10.1186/s12974-021-02216-w
Wang, 2015, Haem-activated promiscuous targeting of artemisinin in Plasmodium falciparum, Nat Commun, 6, 10111, 10.1038/ncomms10111
Wang, 2017, Drug target identification using an iTRAQ-based quantitative chemical proteomics approach-based on a target profiling study of andrographolide, Methods Enzymol, 586, 291, 10.1016/bs.mie.2016.09.049
Yu, 2012, clusterProfiler: an R package for comparing biological themes among gene clusters, OMICS, 16, 284, 10.1089/omi.2011.0118
Dai, 2018, Modulation of protein-interaction states through the cell cycle, Cell, 173, 1481, 10.1016/j.cell.2018.03.065
Jafari, 2014, The cellular thermal shift assay for evaluating drug target interactions in cells, Nat Protoc, 9, 2100, 10.1038/nprot.2014.138
Trott, 2010, AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading, J Comput Chem, 31, 455, 10.1002/jcc.21334
Liu, 2012, Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells, Nat Chem Biol, 8, 486, 10.1038/nchembio.935
Chen, 2020, Celastrol induces ROS-mediated apoptosis via directly targeting peroxiredoxin-2 in gastric cancer cells, Theranostics, 10, 10290, 10.7150/thno.46728
Mucha, 2019, Development and characterization of a new inhibitor of heme oxygenase activity for cancer treatment, Arch Biochem Biophys, 671, 130, 10.1016/j.abb.2019.07.002
Rhee, 2001, Peroxiredoxin, a novel family of peroxidases, IUBMB Life, 52, 35, 10.1080/15216540252774748
Rhee, 2005, Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling, Free Radic Biol Med, 38, 1543, 10.1016/j.freeradbiomed.2005.02.026
Lu, 2019, Identification of PRDX6 as a regulator of ferroptosis, Acta Pharmacol Sin, 40, 1334, 10.1038/s41401-019-0233-9
Abo, 2018, Isotopically-labeled iodoacetamide-alkyne probes for quantitative cysteine-reactivity profiling, Mol Pharm, 15, 743, 10.1021/acs.molpharmaceut.7b00832
Zhang, 2018, Celastrol binds to its target protein via specific noncovalent interactions and reversible covalent bonds, Chem Commun (Camb), 54, 12871, 10.1039/C8CC06140H
Pradhan-Sundd, 2018, Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis, Hepatology, 67, 2320, 10.1002/hep.29585
Garcia-Tsao, 2017, Portal hypertensive bleeding in cirrhosis: risk stratification, diagnosis, and management: 2016 practice guidance by the American Association for the study of liver diseases, Hepatology, 65, 310, 10.1002/hep.28906
Tomita, 2014, Free cholesterol accumulation in hepatic stellate cells: mechanism of liver fibrosis aggravation in nonalcoholic steatohepatitis in mice, Hepatology, 59, 154, 10.1002/hep.26604
Bian, 2017, Magnesium isoglycyrrhizinate promotes the activated hepatic stellate cells apoptosis via endoplasmic reticulum stress and ameliorates fibrogenesis in vitro and in vivo, Biofactors, 43, 836, 10.1002/biof.1390
Zhang, 2018, Artesunate-induced mitophagy alters cellular redox status, Redox Biol, 19, 263, 10.1016/j.redox.2018.07.025
Wang, 2016, In situ proteomic profiling of curcumin targets in HCT116 colon cancer cell line, Sci Rep, 6, 22146, 10.1038/srep22146
Wang, 2014, A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis, Mol Cell Proteomics, 13, 876, 10.1074/mcp.M113.029793
Lovatt, 2020, Peroxiredoxin-1 regulates lipid peroxidation in corneal endothelial cells, Redox Biol, 30, 101417, 10.1016/j.redox.2019.101417
Knaus, 2021, Oxidants in physiological processes, 27
Zhao, 2015, Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I, Chem Sci, 6, 4124, 10.1039/C5SC00633C
Wood, 2003, Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling, Science, 300, 650, 10.1126/science.1080405
Gozzelino, 2010, Mechanisms of cell protection by heme oxygenase-1, Annu Rev Pharmacol Toxicol, 50, 323, 10.1146/annurev.pharmtox.010909.105600
Chiang, 2018, A dual role of heme oxygenase-1 in cancer cells, Int J Mol Sci, 20, 39, 10.3390/ijms20010039
Yang, 2013, The many faces of HMGB1: molecular structure–functional activity in inflammation, apoptosis, and chemotaxis, J Leukoc Biol, 93, 865, 10.1189/jlb.1212662
Wu, 2021, HMGB1 regulates ferroptosis through Nrf2 pathway in mesangial cells in response to high glucose, Biosci Rep, 41, 10.1042/BSR20202924
Yagoda, 2007, RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels, Nature, 447, 864, 10.1038/nature05859
Yang, 2020, Nedd4 ubiquitylates VDAC2/3 to suppress erastin-induced ferroptosis in melanoma, Nat Commun, 11, 433, 10.1038/s41467-020-14324-x