Cdh1-mediated Skp2 degradation by dioscin reprogrammes aerobic glycolysis and inhibits colorectal cancer cells growth
Li Zhou1, Xinfang Yu2, Ming Li3,4, Guanghui Gong1, Wenbin Liu5, Tian Li6, Huilan Zuo6, Wei Li7, Feng Gao6, Haidan Liu8,9
1Department of Pathology, Xiangya Hospital of Central South University, Changsha, Hunan 410008, PR China
2Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA
3Changsha Stomatological Hospital, Changsha, Hunan 410004, PR China
4School of Stomatology, Hunan University of Chinese Medicine, Changsha, Hunan 410208, PR China
5Department of Pathology, Hunan Cancer Hospital, Changsha, Hunan 410013, PR China
6Department of Ultrasonography, The Third Xiangya Hospital of Central South University, Changsha, Hunan, 410013, PR China
7Department of Radiology, The Third Xiangya Hospital of Central South University, Changsha, Hunan, 410013, PR China
8Department of Cardiovascular Surgery, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China
9Clinical Center for Gene Diagnosis and Therapy, The Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, PR China