Causal Role of the Sensorimotor Cortex in Action Simulation: Neuropsychological Evidence

Journal of Cognitive Neuroscience - Tập 23 Số 8 - Trang 2068-2078 - 2011
Barbara Tomasino1, Miran Škrap2, Raffaella I. Rumiati3
11IRCCS “E. Medea,” San Vito al Tagliamento (PN), Italy
22Unità Operativa di Neurochirurgia, Azienda Ospedaliera S. Maria della Misericordia, Udine, Italy
33Cognitive Neuroscience Sector, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Trieste, Italy

Tóm tắt

Abstract Interest in sensorimotor cortex involvement in higher cognitive functions has recently been revived, although whether the cortex actually contributes to the simulation of body part movements has not yet been established. Neurosurgical patients with selective lesions to the hand sensorimotor representation offer a unique opportunity to demonstrate that the sensorimotor cortex plays a causal role in hand action simulations. Patients with damage to hand representation showed a selective deficit in simulating hand movements compared with object movements (Experiment 1). This deficit extended to objects when the patients imagined moving them with their own hands while maintaining the ability to visualize them rotating in space (Experiment 2). The data provide conclusive evidence for a causal role of the sensorimotor cortex in the continuous update of sensorimotor representations while individuals mentally simulate motor acts.

Từ khóa


Tài liệu tham khảo

Barnes, 2000, Cortical activity during rotational and linear transformations., Neuropsychologia, 38, 1148, 10.1016/S0028-3932(00)00025-7

Binkofski, 2002, Neural activity in human primary motor cortex areas 4a and 4p is modulated differentially by attention to action., Journal of Neurophysiology, 88, 514, 10.1152/jn.2002.88.1.514

Bode, 2007, Different strategies do not moderate primary motor cortex involvement in mental rotation: A TMS study., Behavioral and Brain Functions, 3, 38, 10.1186/1744-9081-3-38

Brett, 2001, Spatial normalization of brain images with focal lesions using cost function masking., Neuroimage, 14, 486, 10.1006/nimg.2001.0845

Burnod, 1992, Visuomotor transformations underlying arm movements toward visual targets: A neural network model of cerebral cortical operations., Journal of Neuroscience, 12, 1435, 10.1523/JNEUROSCI.12-04-01435.1992

Carpenter, 1999, Graded functional activation in the visuospatial system with the amount of task demand., Journal of Cognitive Neuroscience, 11, 9, 10.1162/089892999563210

Cohen, 1996, Changes in cortical activity during mental rotation. A mapping study using functional MRI., Brain, 119, 89, 10.1093/brain/119.1.89

Corradi-Dell'Acqua, 2009, What is the position of an arm relative to the body? Neural correlates of body schema and body structural description., Journal of Neuroscience, 29, 4162, 10.1523/JNEUROSCI.4861-08.2009

de Lafuente, 2004, Language abilities of motor cortex., Neuron, 41, 178, 10.1016/S0896-6273(04)00004-2

de Lange, 2005, Neural topography and content of movement representations., Journal of Cognitive Neuroscience, 17, 97, 10.1162/0898929052880039

De Renzi, 1982, Modality-specific and supramodal mechanisms of apraxia., Brain, 105, 301, 10.1093/brain/105.2.301

De Renzi, 1980, Imitating gestures. A quantitative approach to ideomotor apraxia., Archives of Neurology, 37, 6, 10.1001/archneur.1980.00500500036003

Edgeworth, 1998, The balloons test.

Ehrsson, 2003, Imagery of voluntary movement of fingers, toes, and tongue activates corresponding body-part-specific motor representations., Journal of Neurophysiology, 90, 3304, 10.1152/jn.01113.2002

Eisenegger, 2007, The involvement of primary motor cortex in mental rotation revealed by transcranial magnetic stimulation., European Journal of Neuroscience, 25, 1240, 10.1111/j.1460-9568.2007.05354.x

Fadiga, 1999, Corticospinal excitability is specifically modulated by motor imagery: A magnetic stimulation study., Neuropsychologia, 37, 147, 10.1016/S0028-3932(98)00089-X

Fadiga, 2005, Human motor cortex excitability during the perception of others' action., Current Opinion in Neurobiology, 15, 213, 10.1016/j.conb.2005.03.013

Floel, 2003, Language perception activates the hand motor cortex: Implications for motor theories of speech perception., European Journal of Neuroscience, 18, 704, 10.1046/j.1460-9568.2003.02774.x

Ganis, 2000, Transcranial magnetic stimulation of primary motor cortex affects mental rotation., Cerebral Cortex, 10, 175, 10.1093/cercor/10.2.175

Georgopoulos, 2000, Neural aspects of cognitive motor control., Current Opinion in Neurobiology, 10, 238, 10.1016/S0959-4388(00)00072-6

Georgopoulos, 1989, Mental rotation of the neuronal population vector., Science, 243, 234, 10.1126/science.2911737

Goldenberg, 2008, Apraxia and the parietal lobes., Neuropsychologia, 47, 1449, 10.1016/j.neuropsychologia.2008.07.014

Harris, 2000, Selective right parietal lobe activation during mental rotation: A parametric PET study., Brain, 123, 65, 10.1093/brain/123.1.65

Jeannerod, 1999, Mental imaging of motor activity in humans., Current Opinion in Neurobiology, 9, 735, 10.1016/S0959-4388(99)00038-0

Johnson, 2000, Imagining the impossible: Intact motor representations in hemiplegics., NeuroReport, 11, 729, 10.1097/00001756-200003200-00015

Kasses, 2008, The suppressive influence of SMA on M1 in motor imagery revealed by fMRI and dynamic causal modeling., Neuroimage, 40, 828, 10.1016/j.neuroimage.2007.11.040

Kosslyn, 1998, Mental rotation of objects versus hands: Neural mechanisms revealed by positron emission tomography., Psychophysiology, 35, 151, 10.1111/1469-8986.3520151

Kosslyn, 2001, Imagining rotation by endogenous versus exogenous forces: Distinct neural mechanisms., NeuroReport, 12, 2519, 10.1097/00001756-200108080-00046

Luzzatti, 1996, Aachener Aphasie Test.

Masumoto, 2006, Reactivation of physical motor information in the memory of action events., Brain Research, 1101, 102, 10.1016/j.brainres.2006.05.033

Mutsaarts, 2007, Impaired motor imagery in right hemiparetic cerebral palsy., Neuropsychologia, 45, 853, 10.1016/j.neuropsychologia.2006.08.020

Oldfield, 1971, The assessment and analysis of handedness: The Edinburgh inventory., Neuropsychologia, 9, 97, 10.1016/0028-3932(71)90067-4

Parsons, 1987, Imagined spatial transformation of one's body., Journal of Experimental Psychology: General, 116, 172, 10.1037/0096-3445.116.2.172

Parsons, 1987, Imagined spatial transformations of one's hands and feet., Cognitive Psychology, 19, 178, 10.1016/0010-0285(87)90011-9

Parsons, 1994, Temporal and kinematic properties of motor behavior reflected in mentally simulated action., Journal of Experimental Psychology: Human Perception and Performance, 20, 709

Parsons, 1995, Use of implicit motor imagery for visual shape discrimination as revealed by PET., Nature, 375, 54, 10.1038/375054a0

Parsons, 1998, Cerebrally lateralized mental representations of hand shape and movement., Journal of Neuroscience, 18, 6539, 10.1523/JNEUROSCI.18-16-06539.1998

Porro, 2000, Ipsilateral involvement of primary motor cortex during motor imagery., European Journal of Neuroscience, 12, 3059, 10.1046/j.1460-9568.2000.00182.x

Porro, 1996, Primary motor and sensory cortex activation during motor performance and motor imagery: A functional magnetic resonance imaging study., Journal of Neuroscience, 16, 7688, 10.1523/JNEUROSCI.16-23-07688.1996

Ratcliff, 1979, Spatial thought, mental rotation and the right cerebral hemisphere., Neuropsychologia, 17, 49, 10.1016/0028-3932(79)90021-6

Richter, 2000, Motor area activity during mental rotation studied by time-resolved single-trial fMRI., Journal of Cognitive Neuroscience, 12, 310, 10.1162/089892900562129

Rorden, 2000, Stereotaxic display of brain lesions., Behavioural Neurology, 12, 191, 10.1155/2000/421719

Sauner, 2006, No evidence for a substantial involvement of primary motor hand area in handedness judgements: A transcranial magnetic stimulation study., European Journal of Neuroscience, 23, 2215, 10.1111/j.1460-9568.2006.04731.x

Sekiyama, 1982, Kinesthetic aspects of mental representations in the identification of left and right hands., Perceptual Psychophysics, 32, 89, 10.3758/BF03204268

Shepard, 1971, Mental rotation of three-dimensional objects., Science, 171, 701, 10.1126/science.171.3972.701

Sirigu, 1995, A selective impairment of hand posture for object utilization in apraxia., Cortex, 31, 41, 10.1016/S0010-9452(13)80104-9

Sirigu, 1995, Congruent unilateral impairments for real and imagined hand movements., NeuroReport, 6, 997, 10.1097/00001756-199505090-00012

Solodkin, 2004, Fine modulation in network activation during motor execution and motor imagery., Cerebral Cortex, 14, 1246, 10.1093/cercor/bhh086

Spinnler, 1987, Standardizzazione e taratura italiana di test neuropsicologici., Italian Journal of Neurological Sciences, 8(Suppl.), 1

Stippich, 2002, Somatotopic mapping of the human primary sensorimotor cortex during motor imagery and motor execution by functional magnetic resonance imaging., Neuroscience Letters, 331, 50, 10.1016/S0304-3940(02)00826-1

Tagaris, 1996, Quantitative relations between parietal activation and performance in mental rotation., NeuroReport, 7, 773, 10.1097/00001756-199602290-00022

Tomasino, 2005, The role of primary motor cortex in mental rotation: A TMS study., Cognitive Neuropsychology, 22, 348, 10.1080/02643290442000185

Tomasino, 2005, Mental rotation in a patient with an implanted electrode grid in the motor cortex., NeuroReport, 16, 1795, 10.1097/01.wnr.0000185957.65723.52

Tomasino, 2004, Effects of strategies on mental rotation and hemispheric lateralization: Neuropsychological evidence., Journal of Cognitive Neuroscience, 16, 878, 10.1162/089892904970753

Tzourio-Mazoyer, 2002, Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain., Neuroimage, 15, 273, 10.1006/nimg.2001.0978

Vingerhoets, 2001, Regional brain activity during different paradigms of mental rotation in healthy volunteers: A positron emission tomography study., Neuroimage, 13, 381, 10.1006/nimg.2000.0690

Warrington, 1991, VOSP: The visual object and space perception battery.

Wexler, 1998, Motor processes in mental rotation., Cognition, 68, 77, 10.1016/S0010-0277(98)00032-8

Wohlschläger, 2001, Mental object rotation and the planning of hand movements., Perception & Psychophysics, 63, 709, 10.3758/BF03194431

Wohlschläger, 1998, Mental and manual rotation., Journal of Experimental Psychology: Human Perception and Performance, 24, 397

Wraga, 2003, Implicit transfer of motor strategies in mental rotation., Brain and Cognition, 52, 135, 10.1016/S0278-2626(03)00033-2

Zacks, 2008, Neuroimaging studies of mental rotation: A meta-analysis and review., Journal of Cognitive Neuroscience, 20, 1, 10.1162/jocn.2008.20013

Zacks, 2003, Imagined viewer and object rotations dissociated with event-related FMRI., Journal of Cognitive Neuroscience, 15, 1002, 10.1162/089892903770007399

Thông tin
Thông tin xuất bản

Journal of Cognitive Neuroscience

Tập 23 Số 8

2068-2078

Thông tin tác giả