Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Nature - Tập 403 Số 6765 - Trang 98-103 - 2000
Toshiyuki Nakagawa1, Hong Zhu2, Nobuhiro Morishima3, En Li4, Jin Xu5, Bruce A. Yankner5, Junying Yuan2
1Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
2Department of Cell Biology, Harvard Medical School, Boston, USA
3Biodesign Research Group, RIKEN (the Institute of Physical and Chemical Research), Wako, Japan
4Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, USA
5Department of Neurology, Harvard Medical School and Children's Hospital, Enders 260, Boston, USA

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