Case-control study of vascular endothelial growth factor (VEGF) genetic variability in Alzheimer's disease

Awata, 2002, A common polymorphism in the 5′-untranslated region of the VEGF gene is associated with diabetic retinopathy in type 2 diabetes, Diabetes, 51, 1635, 10.2337/diabetes.51.5.1635 Awata, 2005, Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes, Biochem. Biophys. Res. Commun., 333, 679, 10.1016/j.bbrc.2005.05.167 Cao, 2004, VEGF links hippocampal activity with neurogenesis, learning and memory, Nat. Genet., 36, 827, 10.1038/ng1395 J. Chapuis, J. Tian, J. Shi, F. Bensemain, D. Cottel, C. Lendon, P. Amouyel, D. Mann, J.C. Lambert, Association study of the vascular endothelial growth factor gene with the risk of developing Alzheimer's disease, Neurobiol. Aging, in press. Del Bo, 2005, Vascular endothelial growth factor gene variability is associated with increased risk for AD, Ann. Neurol., 57, 373, 10.1002/ana.20390 Hofman, 1997, Atherosclerosis, apolipoprotein E, and prevalence of dementia and Alzheimer's disease in the Rotterdam Study, Lancet, 349, 151, 10.1016/S0140-6736(96)09328-2 Honig, 2005, Atherosclerosis and AD: analysis of data from the US National Alzheimer's Coordinating Center, Neurology, 64, 494, 10.1212/01.WNL.0000150886.50187.30 Howell, 2005, VEGF polymorphisms and severity of atherosclerosis, J. Med. Genet., 42, 485, 10.1136/jmg.2004.025734 Lambrechts, 2003, VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death, Nat. Genet., 34, 383, 10.1038/ng1211 McKhaan, 1984, Clinical diagnosis of Alzheimer's disease: report of the NINCDA-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, Neurology, 34, 934 Shahbazi, 2002, Vascular endothelial growth factor gene polymorphisms are associated with acute renal allograft rejection, J. Am. Soc. Nephrol., 13, 260, 10.1681/ASN.V131260 Solerte, 2005, Decreased release of the angiogenic peptide vascular endothelial growth factor in Alzheimer's disease: recovering effect with insulin and DHEA sulfate, Dement. Geriatr. Cogn. Disord., 19, 1, 10.1159/000080963 Sopher, 2004, Androgen receptor YAC transgenic mice recapitulate SBMA motor neuronopathy and implicate VEGF164 in the motor neuron degeneration, Neuron, 41, 687, 10.1016/S0896-6273(04)00082-0 Storkebaum, 2004, VEGF: a critical player in neurodegeneration, J. Clin. Invest., 113, 14, 10.1172/JCI20682 Yasuhara, 2004, Neuroprotective effects of vascular endothelial growth factor (VEGF) upon dopaminergic neurons in a rat model of Parkinson's disease, Eur. J. Neurosci., 19, 1494, 10.1111/j.1460-9568.2004.03254.x Zlokovic, 2005, Neurovascular mechanisms of Alzheimer's neurodegeneration, Trends Neurosci., 28, 202, 10.1016/j.tins.2005.02.001