Cardiovascular effects of dexmedetomidine, with or without MK-467, following intravenous administration in cats

Veterinary Anaesthesia and Analgesia - Tập 44 Số 1 - Trang 52-62 - 2017
Bruno H. Pypendop1, Juhana Honkavaara2, Jan E. Ilkiw1
1Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA, USA
2Department of Equine and Small Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland

Tóm tắt

Từ khóa


Tài liệu tham khảo

Abbott, 2005, Heart rate and heart rate variability of healthy cats in home and hospital environments, J Feline Med Surg, 7, 195, 10.1016/j.jfms.2004.12.003

Clineschmidt, 1988, A peripherally acting alpha-2 adrenoceptor antagonist: L- 659,066, J Pharmacol Exp Ther, 245, 32

Granholm, 2006, Evaluation of the clinical efficacy and safety of dexmedetomidine or medetomidine in cats and their reversal with atipamezole, Vet Anaesth Analg, 33, 214, 10.1111/j.1467-2995.2005.00259.x

Honkavaara, 2011, The effects of increasing doses of MK-467, a peripheral alpha(2)-adrenergic receptor antagonist, on the cardiopulmonary effects of intravenous dexmedetomidine in conscious dogs, J Vet Pharmacol Ther, 34, 332, 10.1111/j.1365-2885.2010.01242.x

Honkavaara, 2017, The effect of MK-467, a peripheral α2-adrenoceptor antagonist, on dexmedetomidine-induced sedation and bradycardia after intravenous administration in conscious cats, Vet Anaesth Analg, 44, 42, 10.1111/vaa.12385

Lamont, 2001, Cardiopulmonary evaluation of the use of medetomidine hydrochloride in cats, Am J Vet Res, 62, 1745, 10.2460/ajvr.2001.62.1745

Mahoney, 1991, Changes in oxygen measurements when whole blood is stored in iced plastic or glass syringes, Clin Chem, 37, 1244, 10.1093/clinchem/37.7.1244

McSweeney, 2012, Clinical efficacy and safety of dexmedetomidine used as a preanesthetic prior to general anesthesia in cats, J Am Vet Med Assoc, 240, 404, 10.2460/javma.240.4.404

Murrell, 2005, Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog, Vet Anaesth Analg, 32, 117, 10.1111/j.1467-2995.2005.00233.x

Pypendop, 1998, Hemodynamic effects of medetomidine in the dog: a dose titration study, Vet Surg, 27, 612, 10.1111/j.1532-950X.1998.tb00539.x

Pypendop, 2011, Hemodynamic effects of dexmedetomidine in isoflurane-anesthetized cats, Vet Anaesth Analg, 38, 555, 10.1111/j.1467-2995.2011.00663.x

Raekallio, 2010, The effects of L-659,066, a peripheral α2-adrenoceptor antagonist, and verapamil on the cardiovascular influences of dexmedetomidine in conscious sheep, J Vet Pharmacol Ther, 33, 434, 10.1111/j.1365-2885.2009.01156.x

Rolfe, 2012, Cardiopulmonary and sedative effects of the peripheral α2-adrenoceptor antagonist MK 0467 administered intravenously or intramuscularly concurrently with medetomidine in dogs, Am J Vet Res, 73, 587, 10.2460/ajvr.73.5.587

Selmi, 2003, Evaluation of the sedative and cardiorespiratory effects of dexmedetomidine, dexmedetomidine-butorphanol, and dexmedetomidine-ketamine in cats, J Am Vet Med Assoc, 222, 37, 10.2460/javma.2003.222.37

Siggaard-Andersen, 1988, Measured and derived quantities with modern pH and blood gas equipment: calculation algorithms with 54 equations, Scand J Clin Lab Invest Suppl, 189, 7, 10.1080/00365518809168181