Cardioprotective effects of Amygdalin, a promising antioxidant, on acute myocardial infarction and underlying mechanisms

Journal of Functional Foods - Tập 107 - Trang 105684 - 2023
Yang Boshen1, Zhu Yuankang2,3, Zheng Xinjie4, Li Taixi1, Niu Kaifan1, Wang Zhixiang1, Duan Junli3, Shen Chengxing1
1Department of Cardiology, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China
2Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
3Department of Gerontology, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
4Department of Respiratory Medicine, The Fourth Affiliated Hospital, College of Medicine, Zhejiang University, Yiwu, China

Tài liệu tham khảo

Reed, 2017, Acute myocardial infarction, Lancet, 389, 197, 10.1016/S0140-6736(16)30677-8 Charlton, 2020, Oxidative Stress and Inflammation in Renal and Cardiovascular Complications of Diabetes, Biology (Basel), 10 Kurian, 2016, The Role of Oxidative Stress in Myocardial Ischemia and Reperfusion Injury and Remodeling, Revisited. Oxid Med Cell Longev, 2016 1656450 Chen, 2009, Prevention of ischemia/reperfusion-induced cardiac apoptosis and injury by melatonin is independent of glutathione peroxdiase 1, Journal of Pineal Research, 46, 235, 10.1111/j.1600-079X.2008.00654.x Rodrigo, 2013, Cardioprotection against ischaemia/reperfusion by vitamins C and E plus n-3 fatty acids: Molecular mechanisms and potential clinical applications, Clinical Science (London, England), 124, 10.1042/CS20110663 Guan, 1999, Time course of free radical production after primary coronary angioplasty for acute myocardial infarction and the effect of vitamin C, Japanese Circulation Journal, 63, 924, 10.1253/jcj.63.924 Ramos, 2017, Effects of a novel ascorbate-based protocol on infarct size and ventricle function in acute myocardial infarction patients undergoing percutaneous coronary angioplasty, Archives of Medical Science, 13, 558, 10.5114/aoms.2016.59713 Khan, 2020, Vitamin C for Cardiac Protection during Percutaneous Coronary Intervention: A Systematic Review of Randomized Controlled Trials, Nutrients, 12, 10.3390/nu12082199 Yao, 2022, Panaxatriol saponin ameliorates myocardial infarction-induced cardiac fibrosis by targeting Keap1/Nrf2 to regulate oxidative stress and inhibit cardiac-fibroblast activation and proliferation, Free Radical Biology & Medicine, 10.1016/j.freeradbiomed.2022.08.016 Lv, 2022, Role of puerarin in pathological cardiac remodeling: A review, Pharmacological Research, 178 106152 Erikel, 2020, Genotoxic and antigenotoxic potential of amygdalin on isolated human lymphocytes by the comet assay, Journal of Food Biochemistry, e13436 Moslehi, 2019, Antioxidant effects of amygdalin on tunicamycin-induced endoplasmic reticulum stress in the mice liver: Cross talk between endoplasmic reticulum stress and oxidative stress., 8, 298 Kung, 2021, Cardioprotective potential of amygdalin against angiotensin II induced cardiac hypertrophy, oxidative stress and inflammatory responses through modulation of Nrf2 and NF-κB activation, Environmental Toxicology, 36, 926, 10.1002/tox.23094 Lee, 2019, The Methodological Trends of Traditional Herbal Medicine Employing Network Pharmacology, Biomolecules, 9, 10.3390/biom9080362 Sun, 2022, Investigation on the mechanism of 2,3,4',5-Tetrahydroxystilbene 2-o-D-glucoside in the treatment of inflammation based on network pharmacology, Computers in Biology and Medicine, 145 105448 Saikia, 2019, Molecular Docking: Challenges, Advances and its Use in Drug Discovery Perspective, Current Drug Targets, 20, 501, 10.2174/1389450119666181022153016 Decherchi, 2020, Thermodynamics and Kinetics of Drug-Target Binding by Molecular Simulation, Chemical Reviews, 120, 12788, 10.1021/acs.chemrev.0c00534 Nickel J, Gohlke B-O, Erehman J, Banerjee P, Rong WW, Goede A, et al. SuperPred: update on drug classification and target prediction. Nucleic Acids Res 2014; 42 (Web Server issue): W26-W31. doi: 10.1093/nar/gku477. Liu X, Ouyang S, Yu B, Liu Y, Huang K, Gong J, et al. PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach. Nucleic Acids Res 2010; 38 (Web Server issue): W609-W614. doi: 10.1093/nar/gkq300. Wang, 2016, Enhancing the Enrichment of Pharmacophore-Based Target Prediction for the Polypharmacological Profiles of Drugs, Journal of Chemical Information and Modeling, 56, 1175, 10.1021/acs.jcim.5b00690 Wang, 2017, PharmMapper 2017 update: A web server for potential drug target identification with a comprehensive target pharmacophore database, Nucleic Acids Research, 45, W356, 10.1093/nar/gkx374 Piñero, 2020, The DisGeNET knowledge platform for disease genomics: 2019 update, Nucleic Acids Research, 48, D845 Stelzer, 2016, The GeneCards Suite: From Gene Data Mining to Disease Genome Sequence Analyses, Current Protocols in Bioinformatics, 54, 10.1002/cpbi.5 Sun, 2023, Anticancer Structure-activity Relationships and Potential Target Exploration of the Natural Product Gypsogenin., 8, e202300072 Lu, 2023, Targeting WWP1 ameliorates cardiac ischemic injury by suppressing KLF15-ubiquitination mediated myocardial inflammation, Theranostics, 13, 417, 10.7150/thno.77694 Lin, 2022, Amygdalin Induced Mitochondria-Mediated Apoptosis of Lung Cancer Cells via Regulating NF[Formula: See text]B-1/NF[Formula: See text]B Signaling Cascade in Vitro and in Vivo, The American Journal of Chinese Medicine, 50, 1361, 10.1142/S0192415X22500586 Khadri, 2021, Impact of Epithelial-Mesenchymal Transition on the Immune Landscape in Breast Cancer, Cancers (Basel), 13, 10.3390/cancers13205099 Rio, 2010, Purification of RNA using TRIzol (TRI reagent), Cold Spring Harbor protocols, 2010, 10.1101/pdb.prot5439 Rout, 2020, Targeted pharmacotherapy for ischemia reperfusion injury in acute myocardial infarction, Expert Opinion on Pharmacotherapy, 21, 1851, 10.1080/14656566.2020.1787987 Benjamin, 2019, Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association, Circulation, 139, 10.1161/CIR.0000000000000659 Zhao, 2021, Opportunities and Challenges in Myocardial Ischemia-Reperfusion Injury, Oxidative Medicine and Cellular Longevity, 2021 9929687 Hausenloy, 2013, Myocardial ischemia-reperfusion injury: A neglected therapeutic target, The Journal of Clinical Investigation, 123, 10.1172/JCI62874 Hausenloy, 2016, Ischaemic conditioning and targeting reperfusion injury: A 30 year voyage of discovery, Basic Research in Cardiology, 111, 70, 10.1007/s00395-016-0588-8 Choo, 2017, Infarcted Myocardium-Primed Dendritic Cells Improve Remodeling and Cardiac Function After Myocardial Infarction by Modulating the Regulatory T Cell and Macrophage Polarization, Circulation, 135, 1444, 10.1161/CIRCULATIONAHA.116.023106 Frangogiannis, 2014, The inflammatory response in myocardial injury, repair, and remodelling, Nature Reviews. Cardiology, 11, 255, 10.1038/nrcardio.2014.28 Ursini, 2016, Redox homeostasis: The Golden Mean of healthy living, Redox Biology, 8, 205, 10.1016/j.redox.2016.01.010 Wilmes, 2020, Increased inducible nitric oxide synthase (iNOS) expression in human myocardial infarction, International Journal of Legal Medicine, 134, 575, 10.1007/s00414-019-02051-y Li, 2014, Overexpression of inducible nitric oxide synthase impairs the survival of bone marrow stem cells transplanted into rat infarcted myocardium, Life Sciences, 106, 50, 10.1016/j.lfs.2014.04.020 Feng, 2001, Increased inducible nitric oxide synthase expression contributes to myocardial dysfunction and higher mortality after myocardial infarction in mice, Circulation, 104, 700, 10.1161/hc3201.092284 Zhu, 2019, Z-Ligustilide protects vascular endothelial cells from oxidative stress and rescues high fat diet-induced atherosclerosis by activating multiple NRF2 downstream genes, Atherosclerosis, 10.1016/j.atherosclerosis.2019.02.010 Tonelli, 2018, Transcriptional Regulation by Nrf2, Antioxidants & Redox Signaling, 29, 1727, 10.1089/ars.2017.7342 Torrente, 2022, Targeting NRF2 and Its Downstream Processes: Opportunities and Challenges, Annual Review of Pharmacology and Toxicology, 62, 279, 10.1146/annurev-pharmtox-052220-104025 Huang, 2020, Attenuation of Lipopolysaccharide-Induced Acute Lung Injury by Hispolon in Mice, Through Regulating the TLR4/PI3K/AKT/mTOR and Keap1/Nrf2/HO-1 Pathways, and Suppressing Oxidative Stress-Mediated ER Stress-Induced Apoptosis and Autophagy, Nutrients, 12, 10.3390/nu12061742 Jiang, 2021, CTRP13 Protects H9c2 Cells Against Hypoxia/Reoxygenation (H/R)-Induced Injury Via Regulating the AMPK/Nrf2/ARE Signaling Pathway, Cell Transplantation, 30 9636897211033275 Ashrafian, 2012, Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway, Cell Metabolism, 15, 361, 10.1016/j.cmet.2012.01.017 Cao, 2015, A novel mechanism for cytoprotection against hypoxic injury: δ-opioid receptor-mediated increase in Nrf2 translocation, British Journal of Pharmacology, 172, 1869, 10.1111/bph.13031 Abbate, 2006, Acute myocardial infarction and heart failure: Role of apoptosis, The International Journal of Biochemistry & Cell Biology, 38, 1834, 10.1016/j.biocel.2006.04.010 Sheida, 2022, Potential of natural products in the treatment of myocardial infarction: Focus on molecular mechanisms, Critical Reviews in Food Science and Nutrition Edlich, 2018, BCL-2 proteins and apoptosis: Recent insights and unknowns, Biochemical and Biophysical Research Communications, 500, 26, 10.1016/j.bbrc.2017.06.190 Peña-Blanco, 2018, Bax, Bak and beyond - mitochondrial performance in apoptosis, The FEBS Journal, 285, 416, 10.1111/febs.14186 Liu, 2022, Emodin protects against homocysteine-induced cardiac dysfunction by inhibiting oxidative stress via MAPK and AKT/eNOS/NO signaling pathways, European Journal of Pharmacology, 940 175452 Ma, 2023, Pine pollen extract alleviates ethanol-induced oxidative stress and apoptosis in HepG2 cells via MAPK signaling, Food and Chemical Toxicology, 171 113550 Trang, 2022, Effect on Osteoclast Differentiation and ER Stress Downregulation by Amygdalin and RANKL Binding Interaction, Biomolecules, 12, 10.3390/biom12020256 Wang, 2019, based on network pharmacology and molecular docking, Food & Nutrition Research, 2021, 65 Tan, 2011, Diabetic downregulation of Nrf2 activity via ERK contributes to oxidative stress-induced insulin resistance in cardiac cells in vitro and in vivo, Diabetes, 60, 625, 10.2337/db10-1164 Wang, 2019, Nrf2 signaling attenuates epithelial-to-mesenchymal transition and renal interstitial fibrosis via PI3K/AKT signaling pathways, Experimental and Molecular Pathology, 111 104296 Younis, 2021, Protective effects of myrrh essential oil on isoproterenol-induced myocardial infarction in rats through antioxidant, anti-inflammatory, Nrf2/HO-1 and apoptotic pathways, Journal of Ethnopharmacology, 270 113793 Chen, 2021, Amygdalin alleviates renal injury by suppressing inflammation, oxidative stress and fibrosis in streptozotocin-induced diabetic rats, Life Sciences, 265 118835 Gago-López, 2021, Topical application of an amygdalin analogue reduces inflammation and keratinocyte proliferation in a psoriasis mouse model, Experimental Dermatology, 30, 1662, 10.1111/exd.14390 Wang, 2020, Amygdalin Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and Bone Marrow-Derived Macrophages, Frontiers in Pharmacology, 11 590929 Wang, 2022, Amygdalin attenuates PM2.5-induced human umbilical vein endothelial cell injury via the TLR4/NF-κB and Bcl-2/Bax signaling pathways, Acta Biochimica et Biophysica Sinica (Shanghai), 54, 1476, 10.3724/abbs.2022136 Nair, 2016, A simple practice guide for dose conversion between animals and human, Journal Basic Clinical Pharmacy, 7, 27, 10.4103/0976-0105.177703 He, 2020, Amygdalin - A pharmacological and toxicological review, Journal of Ethnopharmacology, 254 112717 Prabhu, 2016, The Biological Basis for Cardiac Repair After Myocardial Infarction: From Inflammation to Fibrosis, Circulation Research, 119, 10.1161/CIRCRESAHA.116.303577 Zhang, 2022, Dioscin alleviates myocardial infarction injury via regulating BMP4/NOX1-mediated oxidative stress and inflammation, Phytomedicine, 103 154222 Zhu, 2022, Tetrahydrocurcumin improves lipopolysaccharide-induced myocardial dysfunction by inhibiting oxidative stress and inflammation via JNK/ERK signaling pathway regulation, Phytomedicine, 104 154283 Gao, 2022, Identification of antimalarial targets of chloroquine by a combined deconvolution strategy of ABPP and MS-CETSA, Military Medical Research, 9, 30, 10.1186/s40779-022-00390-3 Akyildiz, 2010, Cyanide poisoning caused by ingestion of apricot seeds, Annals of Tropical Paediatrics, 30, 39, 10.1179/146532810X12637745451951