Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats

Journal of Biomedical Research - Tập 25 - Trang 280-286 - 2011
Ashish Kumar Sharma1, Kunal Kishore1, Divya Sharma1, B.P Srinivasan2, Shyam Sunder Agarwal2, Ashok Sharma1, Santosh Kumar Singh1, Samir Gaur1, Vijay Singh Jatav1
1Department of Pharmacology, Gyan Vihar School of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Jaipur (Rajasthan) 302025, India
2Delhi Institute of Pharmaceutical Sciences & Research, Department of Pharmacology, Pushpvihar, Sector-III. New Delhi 110017, India

Tài liệu tham khảo

Roden, 2006, Antiarrhythmie Drugs, 899 Thireau, 2011, New drugs vs. old concepts: A fresh look at antiarrhythmics, Pharmacol Ther, 10.1016/j.pharmthera.2011.03.003 Nadkarni AK. Tinospora cordifolia (Willd.) Miers. In: Indian meteria medica. 3rd Revised edition, Bombay, 1954:1221. Chopra, 1958, Tinospora cordifolia (Willd.) Hook. f. (Guduchi), 426 Atal, 1986, Immunomod-ulatory effects of NIM-76, a volatile fraction from Neem oil, J Ethnopharmacol, 18, 133, 10.1016/0378-8741(86)90025-5 Gupta, 1967, Anti-diabetic effects of Tinospora cordifolia-Part I. Effect on fasting blood sugar level, glucose tolerance and adrenaline induced hyper-glycaemia, Ind J Med Res, 55, 733 Singh, 2003, Chemistry and medicinal properties of Tino-spora cordifolia (guduchi), Ind J Pharmacol, 35, 83 Peer, 1989, Therapeutic evaluation of Tinospo-ra cordifolia in CCl4 induced hepatopathy in goats, Ind J Veterinary Med, 9, 154 Sarma, 1995, Al-teration of lethal effects of gamma rays in Swiss albino mice by Tinospora cordifolia, Phytother Res, 9, 589, 10.1002/ptr.2650090811 Prince, 1999, Hypolipidemic action of Tinospora cordifolia roots in alloxan diabetic rats, J Ethnopharmacol, 64, 53, 10.1016/S0378-8741(98)00106-8 Prince, 1999, Hypoglycaemic activity of Syzi-gium cumini seeds: Effect on lipid peroxidation in alloxan diabetic rats, J Ethnopharmacol, 65, 277 Rao, 2005, Car-dioprotective activity of alcoholic extract of Tinospora cordifolia in ischemia-reperfusion induced myocardial infarction in rats, Biol Pharm Bull, 28, 2319, 10.1248/bpb.28.2319 Prince, 2004, Restoration of antioxidant defence by ethanolic Tinospora cordifolia root extract in alloxan-induced diabetic liver and kidney, Phytother Res, 18, 785, 10.1002/ptr.1567 Sharma, 2009, Triple verses glimepiride plus metformin therapy on cardiovascular risk biomarkers and diabetic cardiomyopathy in insulin resistance type 2 diabetes mellitus rats, Eur J Pharm Sci, 38, 433, 10.1016/j.ejps.2009.09.004 Al-Obaid, 1998, Synthesis and biological evaluation of new cyclopenteno[b]-thiophene derivatives as local anesthetic and antiarrhythmic agents, Pharmazie, 53, 24 Francoise, 1986, Comparison of Verapamil and bepridil, two slow channel in-hibitors, in protection against calcium-induced arrhytha-mias. Naunyn-Schmiedeberg's, Arch Pharmacol, 334, 105, 10.1007/BF00498747 Vedavathy, 1991, Chemistry and medicinal properties of tinospora cordifolia (guduchi), J Ethnopharmacol, 33, 1 1975, 131 Friedman, 1955, The clinical significance of the magnesium: calcium ratio, Clin Chem, 1, 125, 10.1093/clinchem/1.2.125 Gross, 1903, Die Bedeutung der. Salze. L6sungffir das isolierte S/iugetierherz. Pfliigers, Arch Ges Physiol, 99, 264, 10.1007/BF01666806 Grumbach, 1954, Factors related to the initiation of ventricular fibrillation in the isolated heart: Effect of calcium and potassium, Circ Res, 2, 452, 10.1161/01.RES.2.5.452 Trautwein, 1963, Generation and conduction of impulses in the heart as affected by drugs, Pharmacol Rev, 15, 277 Temte, 1967, Effect of calcium concentration on the transmembrane potentials of Purkinje fibers, Circ Res, 20, 32, 10.1161/01.RES.20.1.32 Hoffman, 1960, Cardiac Arrhythmias, 263