Cardiac alpha- and beta-adrenergic receptor alterations in diabetic cardiomyopathy

Fein, F. S., L. B. Kornstein, J. E. Strobeck, J. M. Capasso, E. H. Sonnenblick: Altered myocardial mechanics in diabetic rats. Circulat. Res.47, 922–933 (1980).

Penpargkul, S., T. Schaible, T. Yipintsoi, J. Scheuer: The effect of diabetes on performance and metabolism of rat hearts. Circulat. Res.47, 911–921 (1980).

Senges, J., J. Brachmann, D. Pelzer, C. Hasslacher, E. Weihe, W. Kubler: Altered cardiac automaticity and conduction in experimental diabetes mellitus. J. Mol. Cell. Cardiol.12, 1341–1351 (1980).

Tarach, J. S.: Histomorphological and ultrastructural studies of a rat myocardium in experimental conditions. Z. mikr.-anat. Forsch.90, 1145–1157 (1976).

Penpargkul, S., F. Fein, E. H. Sonnenblick, J. Scheuer: Depressed cardiac sarcoplasmic reticular function from diabetic rats. J. Mol. Cell. Cardiol.13, 303–309 (1981).

Pierce, G. N., N. S. Dhalla: Cardiac myofibrillar ATPase activity in diabetic rats. J. Mol. Cell. Cardiol.13, 1063–1069 (1981).

Puckett, S. W., W. J. Reddy: A decrease in the malate-aspartate shuttle and glutamate translocase activity in heart mitochondria from alloxan-diabetic rats. J. Mol. Cell. Cardiol.11, 173–187 (1979).

Ingebretsen, C. G., P. Moreau, C. Hawelu-Johnson, W. R. Ingebretsen: Performance of diabetic rat hearts: effects of anoxia and increased work. Amer. J. Physiol.239, H614-H620 (1980).

Ingebretsen, W. R., C. Peralta, M. Monsher, L. K. Wagner, C. G. Ingebretsen: Diabetes alters the myocardial cAMP-protein kinase cascade system. Amer. J. Physiol.240, H375-H382 (1981).

Savarese, J. J., B. A. Berkowitz: β-adrenergic receptor decrease in diabetic rat hearts. Life Sci.25, 2075–2078 (1979).

Singal, P. K., K. Prasad: Extracellular calcium and positive inotropy of ionophore (X537-A) in cardiac muscle. Japan. J. Physiol.26, 529–535 (1976).

Williams, R. S., R. J. Lefkowitz: Thyroid hormone regulation of alpha-adrenergic receptors: Studies in rat myocardium. J. Cardiovasc. Pharmacol.1, 181–189 (1979).

Lowry, O. H., N. J. Rosebrough, A. L. Farr, A. J. Randall: Protein measurement with the Folin Phenol reagent. J. Biol. Chem.193, 265–275 (1951).

Nakashima, M., H. Tsuru, T. Shigei: Stimulant action of methoxamine in the isolated atria of normal and 6-propyl-2-thiouracil-fed rats. Japan. J. Pharmacol.23, 307–317 (1973).

Lee, J. C., R. R. Fripp, S. E. Downing: Supersensitivity of diabetic hearts to alpha adrenoreceptor stimulation with methoxamine. Fed. Proc.40, 605 (1981).

Rerup, C. C.: Drugs producing diabetes through damage of the insulin secreting cells. Pharmacol. Rev.22, 485–518 (1970).

Limas, C. J.: Increased number of β-adrenergic receptors in the hypertrophied myocardium. Biochim. Biophys. Acta588, 174–178 (1979).

Karliner, J. S., P. Barnes, M. Brown, C. Dollery: Chronic heart failure in the guinea pig increases cardiac α1 and β-adrenoreceptors. Europ. J. Pharmacol.67, 115–118 (1980).

Bobik, A., P. Korner, V. Carson, J. R. Oliver: Cardiac β-adrenoreceptors and adenyl cyclase activity in rabbit heart during conditions of altered sympathetic activity. Circulat. Res.46 (Suppl. I), 43—44 (1980).

Christensen, N. J.: Plasma norepinephrine and epinephrine in untreated diabetics, during fasting and after insulin administration. Diabetes23, 1–8 (1974).

Paulson, D. J., D. Shetlar, K. E. Light: Catecholamine levels in the heart, serum and adrenals of experimental diabetic rats. Fed. Proc.39, 637 (1980).

Mickey, J., R. Tate, R. J. Lefkowitz: Subsensitivity of adenylate cyclase and decreased β-adrenergic receptor binding after chronic exposure to (−) isoproterenol in vitro. J. Biol. Chem.250, 5727–5729 (1975).

Fein, F., J. E. Strobeck, A. Malhotra, J. Scheuer, E. H. Sonnenblick: Reversibility of diabetic cardiomyopathy with insulin in rats. Circulat. Res.49, 1251–1261 (1981).

Ciaraldi, T. P., G. V. Marinetti: Thyroxine and propylthiouracil effects in vivo on alpha and beta-adrenergic receptors in rat heart. Biochem. Biophys. Res. Commun.78, 984–991 (1977).

Sharma, V. K., S. P. Banerjee: Alpha-adrenergic receptors in rat heart: Effects of thyroidectomy. J. Biol. Chem.253, 5277–5279 (1978).

McConnaughey, M. M., L. R. Jones, A. M. Watanabe, H. R. Besch, L. T. Williams, R. J. Lefkowitz: Thyroxine and propylthiouracil effects on alpha- and beta-adrenergic receptor number, ATPase activities, and sialic acid content of rat cardiac membrane vesicles. J. Cardiovas. Pharmacol.1, 609–623 (1979).

Wince, L. C., C. O. Rutledge: The effect of dietary lipid on the binding of [3H] dihydroalprenolol and adenylate cyclase activity in rat atria. J. Pharmacol. Exp. Ther.219, 625–631 (1981).