Cardiac Society of Australia and New Zealand Position Statement: Coronary Artery Calcium Scoring

Stary, 1995, A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association, Circulation, 92, 1355, 10.1161/01.CIR.92.5.1355

Lenk, 1927, Röntgendiagnose der Koronarsklerose in vivo, Fortschr Geb Rontgenstrahlen, 35, 1265

Blankenhorn, 1959, Calcification of the coronary arteries, Am J Roentgenol Radium Ther Nucl Med, 81, 772

Margolis, 1980, The diagnostic and prognostic significance of coronary artery calcification. A report of 800 cases, Radiology, 137, 609, 10.1148/radiology.137.3.7444045

Reinmuller, 1987, Detection of coronary artery calcification by computed tomography, Dynamic Cardiovasc Imaging, 1, 139

Schmermund, 2014, The Agatston calcium score: a milestone in the history of cardiac CT, J Cardiovasc Comput Tomogr, 8, 414, 10.1016/j.jcct.2014.09.008

Agatston, 1990, Quantification of coronary artery calcium using ultrafast computed tomography, J Am Coll Cardiol, 15, 827, 10.1016/0735-1097(90)90282-T

Callister, 1998, Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method, Radiology, 208, 807, 10.1148/radiology.208.3.9722864

Callister, 2000, Sensitivity of two electron beam tomography protocols for the detection and quantification of coronary artery calcium, AJR Am J Roentgenol, 175, 1743, 10.2214/ajr.175.6.1751743

Moselewski, 2005, Calcium concentration of individual coronary calcified plaques as measured by multidetector row computed tomography, Circulation, 111, 3236, 10.1161/CIRCULATIONAHA.104.489781

Mahnken, 2002, Variation of the coronary calcium score depending on image reconstruction interval and scoring algorithm, Invest Radiol, 37, 496, 10.1097/00004424-200209000-00004

Becker, 2001, Coronary artery calcium measurement: agreement of multirow detector and electron beam CT, AJR Am J Roentgenol, 176, 1295, 10.2214/ajr.176.5.1761295

Detrano, 2005, Coronary calcium measurements: effect of CT scanner type and calcium measure on rescan reproducibility—MESA study, Radiology, 236, 477, 10.1148/radiol.2362040513

Morin, 2003, Radiation dose in computed tomography of the heart, Circulation, 107, 917, 10.1161/01.CIR.0000048965.56529.C2

Mahnken, 2003, Detection of coronary calcifications: feasibility of dose reduction with a body weight-adapted examination protocol, AJR Am J Roentgenol, 181, 533, 10.2214/ajr.181.2.1810533

Voros, 2011, Journal of Cardiovascular Computed Tomography, 5, 75, 10.1016/j.jcct.2011.01.003

Nakazato, 2009, Coronary artery calcium scoring using a reduced tube voltage and radiation dose protocol with dual-source computed tomography, J Cardiovasc Comput Tomogr, 3, 394, 10.1016/j.jcct.2009.10.002

Kirsch, 2012, Detection of coronary calcium during standard chest computed tomography correlates with multi-detector computed tomography coronary artery calcium score, Int J Cardiovasc Imaging, 28, 1249, 10.1007/s10554-011-9928-9

Otton, 2012, A method for coronary artery calcium scoring using contrast-enhanced computed tomography, Journal of Cardiovascular Computed Tomography, 6, 37, 10.1016/j.jcct.2011.11.004

Deprez, 2013, Controversies about effects of low-kilovoltage MDCT acquisition on Agatston calcium scoring, Journal of Cardiovascular Computed Tomography, 7, 58, 10.1016/j.jcct.2012.11.006

Greenland, 2010, 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, J Am Coll Cardiol, 56, e50, 10.1016/j.jacc.2010.09.001

Guidelines N, 2012

Detrano, 2008, Coronary calcium as a predictor of coronary events in four racial or ethnic groups, N Engl J Med, 358, 1336, 10.1056/NEJMoa072100

Wang, 2005, Is the Framingham coronary heart disease absolute risk function applicable to Aboriginal people?, The Medical Journal of Australia, 182, 66, 10.5694/j.1326-5377.2005.tb06577.x

Ellis, 2011, High calcium scores in patients with a low Framingham risk of cardiovascular (CVS) disease: implications for more accurate CVS risk assessment in New Zealand, N Z Med J, 124, 13

Greenland, 2004, Coronary artery calcium score combined with Framingham score for risk prediction in asymptomatic individuals, JAMA, 291, 210, 10.1001/jama.291.2.210

Budoff, 2007, Long-term prognosis associated with coronary calcification: observations from a registry of 25,253 patients, J Am Coll Cardiol, 49, 1860, 10.1016/j.jacc.2006.10.079

LaMonte, 2005, Coronary artery calcium score and coronary heart disease events in a large cohort of asymptomatic men and women, American Journal of Epidemiology, 162, 421, 10.1093/aje/kwi228

Shaw, 2015, Long-Term Prognosis After Coronary Artery Calcification Testing in Asymptomatic Patients: A Cohort Study, Ann Intern Med, 163, 14, 10.7326/M14-0612

Greenland, 2007, J Am Coll Cardiol, 49, 378, 10.1016/j.jacc.2006.10.001

Raggi, 2004, Prognostic value of coronary artery calcium screening in subjects with and without diabetes, J Am Coll Cardiol, 43, 1663, 10.1016/j.jacc.2003.09.068

Polonsky, 2010, Coronary artery calcium score and risk classification for coronary heart disease prediction, JAMA, 303, 1610, 10.1001/jama.2010.461

Yeboah, 2012, Comparison of novel risk markers for improvement in cardiovascular risk assessment in intermediate-risk individuals, JAMA, 308, 788, 10.1001/jama.2012.9624

Pencina, 2008, Evaluating the added predictive ability of a new marker: from area under the ROC curve to reclassification and beyond, Statistics in Medicine, 27, 157, 10.1002/sim.2929

Erbel, 2010, Coronary risk stratification, discrimination, and reclassification improvement based on quantification of subclinical coronary atherosclerosis: the Heinz Nixdorf Recall study, J Am Coll Cardiol, 56, 1397, 10.1016/j.jacc.2010.06.030

Elias-Smale, 2010, Coronary calcium score improves classification of coronary heart disease risk in the elderly: the Rotterdam study, J Am Coll Cardiol, 56, 1407, 10.1016/j.jacc.2010.06.029

Sarwar, 2009, Diagnostic and prognostic value of absence of coronary artery calcification, JACC Cardiovasc Imaging, 2, 675, 10.1016/j.jcmg.2008.12.031

Blaha, 2009, Absence of coronary artery calcification and all-cause mortality, JACC Cardiovasc Imaging, 2, 692, 10.1016/j.jcmg.2009.03.009

Shareghi, 2007, Prognostic significance of zero coronary calcium scores on cardiac computed tomography, J Cardiovasc Comput Tomogr, 1, 155, 10.1016/j.jcct.2007.10.001

Silverman, 2014, Impact of coronary artery calcium on coronary heart disease events in individuals at the extremes of traditional risk factor burden: the Multi-Ethnic Study of Atherosclerosis, European Heart Journal, 35, 2232, 10.1093/eurheartj/eht508

Valenti, 2015, A 15-Year Warranty Period for Asymptomatic Individuals Without Coronary Artery Calcium: A Prospective Follow-Up of 9,715 Individuals, JACC Cardiovasc Imaging, 10.1016/j.jcmg.2015.01.025

Hoff, 2001, Age and gender distributions of coronary artery calcium detected by electron beam tomography in 35,246 adults, Am J Cardiol, 87, 1335, 10.1016/S0002-9149(01)01548-X

McClelland, 2006, Distribution of coronary artery calcium by race, gender, and age: results from the Multi-Ethnic Study of Atherosclerosis (MESA), Circulation, 113, 30, 10.1161/CIRCULATIONAHA.105.580696

Hoffmann, 2008, Defining normal distributions of coronary artery calcium in women and men (from the Framingham Heart Study), Am J Cardiol, 102, 1136, 10.1016/j.amjcard.2008.06.038

Buse, 2007, Primary prevention of cardiovascular diseases in people with diabetes mellitus: a scientific statement from the American Heart Association and the American Diabetes Association, Circulation, 115, 114, 10.1161/CIRCULATIONAHA.106.179294

Michos, 2006, Framingham risk equation underestimates subclinical atherosclerosis risk in asymptomatic women, Atherosclerosis, 184, 201, 10.1016/j.atherosclerosis.2005.04.004

Lakoski, 2007, Coronary artery calcium scores and risk for cardiovascular events in women classified as “low risk” based on Framingham risk score: the multi-ethnic study of atherosclerosis (MESA), Arch Intern Med, 167, 2437, 10.1001/archinte.167.22.2437

Chao, 2010, The diagnostic accuracy of 256-row computed tomographic angiography compared with invasive coronary angiography in patients with suspected coronary artery disease, European Heart Journal, 31, 1916, 10.1093/eurheartj/ehq072

Gitsioudis, 2014, When do we really need coronary calcium scoring prior to contrast-enhanced coronary computed tomography angiography? Analysis by age, gender and coronary risk factors, PLoS One, 9, e92396, 10.1371/journal.pone.0092396

Hausleiter, 2010, Image quality and radiation exposure with a low tube voltage protocol for coronary CT angiography results of the PROTECTION II Trial, JACC Cardiovasc Imaging, 3, 1113, 10.1016/j.jcmg.2010.08.016

Hosch, 2012, Reduction of radiation exposure and improvement of image quality with BMI-adapted prospective cardiac computed tomography and iterative reconstruction, European Journal of Radiology, 81, 3568, 10.1016/j.ejrad.2011.06.055

Chang, 2009, The coronary artery calcium score and stress myocardial perfusion imaging provide independent and complementary prediction of cardiac risk, J Am Coll Cardiol, 54, 1872, 10.1016/j.jacc.2009.05.071

Knez, 2004, Relation of coronary calcium scores by electron beam tomography to obstructive disease in 2,115 symptomatic patients, Am J Cardiol, 93, 1150, 10.1016/j.amjcard.2004.01.044

Kwon, 2011, Coronary artery calcium scoring does not add prognostic value to standard 64-section CT angiography protocol in low-risk patients suspected of having coronary artery disease, Radiology, 259, 92, 10.1148/radiol.10100886

Pursnani, 2015, Use of coronary artery calcium scanning beyond coronary computed tomographic angiography in the emergency department evaluation for acute chest pain: the ROMICAT II trial, Circ Cardiovasc Imaging, 8, 10.1161/CIRCIMAGING.114.002225

Arad, 2005, Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St. Francis Heart Study randomized clinical trial, J Am Coll Cardiol, 46, 166, 10.1016/j.jacc.2005.02.089

He, 2000, Severity of coronary artery calcification by electron beam computed tomography predicts silent myocardial ischemia, Circulation, 101, 244, 10.1161/01.CIR.101.3.244

Moser, 2003, Coronary calcium screening in asymptomatic patients as a guide to risk factor modification and stress myocardial perfusion imaging, J Nucl Cardiol, 10, 590, 10.1016/S1071-3581(03)00653-6

Douglas, 2008, Circulation, 117, 1478, 10.1161/CIRCULATIONAHA.107.189097

Stone, 2014, 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines, J Am Coll Cardiol, 63, 2889, 10.1016/j.jacc.2013.11.002

Ridker, 2013, Statins: new American guidelines for prevention of cardiovascular disease, Lancet, 382, 1762, 10.1016/S0140-6736(13)62388-0

Blaha, 2011, Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study, Lancet, 378, 684, 10.1016/S0140-6736(11)60784-8

Ridker, 2008, Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein, N Engl J Med, 359, 2195, 10.1056/NEJMoa0807646

Blaha, 2014, Is there a role for coronary artery calcium scoring for management of asymptomatic patients at risk for coronary artery disease?: Clinical risk scores are not sufficient to define primary prevention treatment strategies among asymptomatic patients, Circ Cardiovasc Imaging, 7, 398, 10.1161/CIRCIMAGING.113.000341

Rozanski, 2011, Impact of coronary artery calcium scanning on coronary risk factors and downstream testing the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) prospective randomized trial, J Am Coll Cardiol, 57, 1622, 10.1016/j.jacc.2011.01.019

Nissen, 2006, Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial, JAMA, 295, 1556, 10.1001/jama.295.13.jpc60002

Nicholls, 2010, Intravascular ultrasound-derived measures of coronary atherosclerotic plaque burden and clinical outcome, J Am Coll Cardiol, 55, 2399, 10.1016/j.jacc.2010.02.026

Chow, 2015, Arteriosclerosis, Thrombosis, and Vascular Biology, 35, 981, 10.1161/ATVBAHA.114.304351

Cho, 2012, Circulation, 126, 304, 10.1161/CIRCULATIONAHA.111.081380

Martin, 2014, Dyslipidemia, coronary artery calcium, and incident atherosclerotic cardiovascular disease: implications for statin therapy from the multi-ethnic study of atherosclerosis, Circulation, 129, 77, 10.1161/CIRCULATIONAHA.113.003625

Pursnani, 2015, Guideline-Based Statin Eligibility, Coronary Artery Calcification, and Cardiovascular Events, JAMA, 314, 134, 10.1001/jama.2015.7515

Roberts, 2015, Cost-effectiveness of coronary artery calcium testing for coronary heart and cardiovascular disease risk prediction to guide statin allocation: the Multi-Ethnic Study of Atherosclerosis (MESA), PLoS One, 10, e0116377, 10.1371/journal.pone.0116377

Kalia, 2015, Motivational effects of coronary artery calcium scores on statin adherence and weight loss, Coron Artery Dis, 26, 225, 10.1097/MCA.0000000000000207

Antithrombotic Trialists C, 2009, Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials, Lancet, 373, 1849, 10.1016/S0140-6736(09)60503-1

Berger, 2006, Aspirin for the primary prevention of cardiovascular events in women and men: a sex-specific meta-analysis of randomized controlled trials, JAMA, 295, 306, 10.1001/jama.295.3.306

Seshasai, 2012, Effect of aspirin on vascular and nonvascular outcomes: meta-analysis of randomized controlled trials, Arch Intern Med, 172, 209, 10.1001/archinternmed.2011.628

Wolff, 2009, Aspirin for the primary prevention of cardiovascular events: an update of the evidence for the U.S. Preventive Services Task Force, Ann Intern Med, 150, 405, 10.7326/0003-4819-150-6-200903170-00009

Miedema, 2014, Use of coronary artery calcium testing to guide aspirin utilization for primary prevention: estimates from the multi-ethnic study of atherosclerosis, Circ Cardiovasc Qual Outcomes, 7, 453, 10.1161/CIRCOUTCOMES.113.000690

Paixao, 2015, Disagreement Between Different Definitions of Coronary Artery Calcium Progression, JACC Cardiovasc Imaging, 8, 743, 10.1016/j.jcmg.2014.07.019

Min, 2010, Determinants of coronary calcium conversion among patients with a normal coronary calcium scan: what is the “warranty period” for remaining normal?, J Am Coll Cardiol, 55, 1110, 10.1016/j.jacc.2009.08.088

Alluri, 2015, Distribution and burden of newly detected coronary artery calcium: Results from the Multi-Ethnic Study of Atherosclerosis, J Cardiovasc Comput Tomogr, 9, 337, 10.1016/j.jcct.2015.03.015

Raggi, 2004, Progression of coronary artery calcium and risk of first myocardial infarction in patients receiving cholesterol-lowering therapy, Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 1272, 10.1161/01.ATV.0000127024.40516.ef

Budoff, 2010, Progression of coronary artery calcium predicts all-cause mortality, JACC Cardiovasc Imaging, 3, 1229, 10.1016/j.jcmg.2010.08.018

Budoff, 2013, Progression of coronary calcium and incident coronary heart disease events: MESA (Multi-Ethnic Study of Atherosclerosis), J Am Coll Cardiol, 61, 1231, 10.1016/j.jacc.2012.12.035

Lee, 2009, Insulin resistance independently predicts the progression of coronary artery calcification, American Heart Journal, 157, 939, 10.1016/j.ahj.2009.02.006

Wong, 2004, Relation of coronary calcium progression and control of lipids according to National Cholesterol Education Program guidelines, Am J Cardiol, 94, 431, 10.1016/j.amjcard.2004.05.003

Raggi, 2005, Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES), Circulation, 112, 563, 10.1161/CIRCULATIONAHA.104.512681

Puri, 2015, Impact of statins on serial coronary calcification during atheroma progression and regression, J Am Coll Cardiol, 65, 1273, 10.1016/j.jacc.2015.01.036