Carcinoma cuniculatum of the larynx: a rare clinicopathological entity

Journal of Laryngology and Otology - Tập 122 Số 10 - Trang 1118-1123 - 2008
Roberto Puxeddu1, Daniele Cocco2, Giuseppina Parodo3, G. Mallarini4, M.P. Medda2, Peter A. Brennan5
1Department of Otorhinolaryngology, Queen Alexandra Hospital, Portsmouth, UK
2Department of Surgical Sciences and Organ Transplantations, University of Cagliari, Cagliari, Italy
3Department of Cytomorphology, University of Cagliari, Cagliari, Italy
4Department of Imaging, Policlinico Universitario, Cagliari, Italy
5Department of Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK

Tóm tắt

AbstractObjective:

Carcinoma cuniculatum is a rare variant of low-grade squamous cell carcinoma. We report the second case of carcinoma cuniculatum of the larynx in the literature.

Method:

Case report and review of the world literature concerning carcinoma cuniculatum of the larynx and upper aerodigestive tract.

Results:

A histologically proven carcinoma cuniculatum of the larynx is reported in a 72-year-old man. The patient underwent a supracricoid laryngectomy with crico-hyoidopexy, and was free of disease at 70 months after surgery. We emphasise the clinical presentation, histology and therapeutic approach of this rare tumour.

Conclusion:

To our knowledge this is the second report in the world literature of carcinoma cuniculatum of the larynx. Carcinoma cuniculatum of the larynx must be considered as a distinct ‘clinicopathological entity’ and close cooperation between the clinician and the pathologist is essential for the correct diagnosis of these tumour as regards to the correct classification and therapy.

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