Carbonic anhydrase related protein 8 mutation results in aberrant synaptic morphology and excitatory synaptic function in the cerebellum

Apps, 2005, Anatomical and physiological foundations of cerebellar information processing, Nat. Rev. Neurosci., 6, 297, 10.1038/nrn1646 Araki, 1993, Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells, Biochem. Biophys. Res. Commun., 197, 1267, 10.1006/bbrc.1993.2614 Bravin, 1999, Control of spine formation by electrical activity in the adult rat cerebellum, Proc. Natl. Acad. Sci. U. S. A., 96, 1704, 10.1073/pnas.96.4.1704 Chen, 1997, The mechanism of cAMP-mediated enhancement at a cerebellar synapse, J. Neurosci., 17, 8687, 10.1523/JNEUROSCI.17-22-08687.1997 Dodgson, 1991 Fremeau, 2001, The expression of vesicular glutamate transporters defines two classes of excitatory synapse, Neuron, 31, 247, 10.1016/S0896-6273(01)00344-0 Hirai, 2005, Cbln1 is essential for synaptic integrity and plasticity in the cerebellum, Nat. Neurosci., 8, 1534, 10.1038/nn1576 Hirota, 2003, Carbonic anhydrase-related protein is a novel binding protein for inositol 1,4,5-trisphosphate receptor type 1, Biochem. J., 372, 435, 10.1042/bj20030110 Ichikawa, 2002, Distal extension of climbing fiber territory and multiple innervation caused by aberrant wiring to adjacent spiny branchlets in cerebellar Purkinje cells lacking glutamate receptor delta 2, J. Neurosci., 22, 8487, 10.1523/JNEUROSCI.22-19-08487.2002 Jiao, 2005, Carbonic anhydrase-related protein VIII deficiency is associated with a distinctive lifelong gait disorder in waddles mice, Genetics, 171, 1239, 10.1534/genetics.105.044487 Jun, 1999, Ablation of P/Q-type Ca(2+) channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the alpha(1A)-subunit, Proc. Natl. Acad. Sci. U. S. A., 96, 15245, 10.1073/pnas.96.26.15245 Kashiwabuchi, 1995, Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice, Cell, 81, 245, 10.1016/0092-8674(95)90334-8 Kato, 1990, Sequence of a novel carbonic anhydrase-related polypeptide and its exclusive presence in Purkinje cells, FEBS Lett., 271, 137, 10.1016/0014-5793(90)80390-5 Kim, 2002, Specific plasticity of parallel fiber/Purkinje cell spine synapses by motor skill learning, Neuroreport, 13, 1607, 10.1097/00001756-200209160-00007 Kishore, 2004, C1q and tumor necrosis factor superfamily: modularity and versatility, Trends Immunol., 25, 551, 10.1016/j.it.2004.08.006 Knopfel, 1991, Climbing fibre responses in olivo-cerebellar slice cultures: II. Dynamics of cytosolic calcium in Purkinje cells, Eur. J. Neurosci., 3, 343, 10.1111/j.1460-9568.1991.tb00821.x Konnerth, 1992, Brief dendritic calcium signals initiate long-lasting synaptic depression in cerebellar Purkinje cells, Proc. Natl. Acad. Sci. U. S. A., 89, 7051, 10.1073/pnas.89.15.7051 Kurihara, 1997, Impaired parallel fiber→Purkinje cell synapse stabilization during cerebellar development of mutant mice lacking the glutamate receptor delta2 subunit, J. Neurosci., 17, 9613, 10.1523/JNEUROSCI.17-24-09613.1997 Landsend, 1997, Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses, J. Neurosci., 17, 834, 10.1523/JNEUROSCI.17-02-00834.1997 Lomeli, 1993, The rat delta-1 and delta-2 subunits extend the excitatory amino acid receptor family, FEBS Lett., 315, 318, 10.1016/0014-5793(93)81186-4 Mayat, 1995, Immunoprecipitation, immunoblotting, and immunocytochemistry studies suggest that glutamate receptor delta subunits form novel postsynaptic receptor complexes, J. Neurosci., 15, 2533, 10.1523/JNEUROSCI.15-03-02533.1995 McKay, 2005, Physiological and morphological development of the rat cerebellar Purkinje cell, J. Physiology (Lond.), 567, 829, 10.1113/jphysiol.2005.089383 Miyakawa, 1992, Calcium transients evoked by climbing fiber and parallel fiber synaptic inputs in guinea pig cerebellar Purkinje neurons, J. Neurophysiol., 68, 1178, 10.1152/jn.1992.68.4.1178 Miyazaki, 2003, Subtype switching of vesicular glutamate transporters at parallel fibre-Purkinje cell synapses in developing mouse cerebellum, Eur. J. Neurosci., 17, 2563, 10.1046/j.1460-9568.2003.02698.x Miyazaki, 2004, P/Q-type Ca2+ channel alpha1A regulates synaptic competition on developing cerebellar Purkinje cells, J. Neurosci., 24, 1734, 10.1523/JNEUROSCI.4208-03.2004 Nikonenko, 2002, Activity-induced changes of spine morphology, Hippocampus, 12, 585, 10.1002/hipo.10095 Nogradi, 1997, Carbonic anhydrase II and carbonic anhydrase-related protein in the cerebellar cortex of normal and lurcher mice, Brain Res. Dev. Brain Res., 98, 91, 10.1016/S0165-3806(96)00177-0 Okubo, 2001, Visualization of IP(3) dynamics reveals a novel AMPA receptor-triggered IP(3) production pathway mediated by voltage-dependent Ca(2+) influx in Purkinje cells, Neuron, 32, 113, 10.1016/S0896-6273(01)00464-0 Prange, 2001, Modular transport of postsynaptic density-95 clusters and association with stable spine precursors during early development of cortical neurons, J. Neurosci., 21, 9325, 10.1523/JNEUROSCI.21-23-09325.2001 Rhyu, 1999, An ultrastructural study of granule cell/Purkinje cell synapses in tottering (tg/tg), leaner (tg(la)/tg(la)) and compound heterozygous tottering/leaner (tg/tg(la)) mice, Neuroscience, 90, 717, 10.1016/S0306-4522(98)00518-1 Rhyu, 1999, Morphologic investigation of rolling mouse Nagoya (tg(rol)/tg(rol)) cerebellar Purkinje cells: an ataxic mutant, revisited, Neurosci. Lett., 266, 49, 10.1016/S0304-3940(99)00254-2 Sjoblom, 1996, Two point mutations convert a catalytically inactive carbonic anhydrase-related protein (CARP) to an active enzyme, FEBS Lett., 398, 322, 10.1016/S0014-5793(96)01263-X Sotelo, 1975, Climbing fiber deafferentation: its action on Purkinje cell dendritic spines, Brain Res., 98, 574, 10.1016/0006-8993(75)90374-1 Takahashi, 2000, Cannabinoid receptor modulation of synapses received by cerebellar Purkinje cells, J. Neurophysiol., 83, 1167, 10.1152/jn.2000.83.3.1167 Takayama, 1995, Light- and electron-microscopic localization of the glutamate receptor channel delta 2 subunit in the mouse Purkinje cell, Neurosci. Lett., 188, 89, 10.1016/0304-3940(95)11403-J Takeuchi, 2005, Control of synaptic connection by glutamate receptor delta2 in the adult cerebellum, J. Neurosci., 25, 2146, 10.1523/JNEUROSCI.4740-04.2005 Westenbroek, 1995, Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channels, J. Neurosci., 15, 6403, 10.1523/JNEUROSCI.15-10-06403.1995 Xu-Friedman, 2001, Three-dimensional comparison of ultrastructural characteristics at depressing and facilitating synapses onto cerebellar Purkinje cells, J. Neurosci., 21, 6666, 10.1523/JNEUROSCI.21-17-06666.2001