Capsaicin-induced transcriptional changes in hypothalamus and alterations in gut microbial count in high fat diet fed mice

The Journal of Nutritional Biochemistry - Tập 25 - Trang 893-902 - 2014
Ritesh K. Baboota1, Nida Murtaza1, Sneha Jagtap2, Dhirendra P. Singh1, Aniket Karmase2, Jaspreet Kaur3, Kamlesh K. Bhutani2, Ravneet K. Boparai4, Louis S. Premkumar5, Kanthi Kiran Kondepudi1, Mahendra Bishnoi1
1National Agri-Food Biotechnology Institute, SAS Nagar, Punjab, India 160071
2National Institute of Pharmaceutical Education and Research, SAS Nagar, Punjab, India 160062
3Department of Biotechnology, University Institute of Engineering and Technology, Panjab University, Chandigarh, India 160025
4Department of Biochemistry, Panjab University, Chandigarh, India 160014
5Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL 62702, USA

Tài liệu tham khảo

World Health Statistics 2012. Powell, 2011, New drug targets for the treatment of obesity, Clin Pharmacol Ther, 90, 40, 10.1038/clpt.2011.82 Meydani, 2010, Dietary polyphenols and obesity, Nutrients, 2, 737, 10.3390/nu2070737 Williams, 2013, Vegetables containing phytochemicals with potential anti-obesity properties: a review, Food Res Int, 52, 323, 10.1016/j.foodres.2013.03.015 Sharma, 2013, Mechanisms and clinical uses of capsaicin, Eur J Pharmacol, 720, 55, 10.1016/j.ejphar.2013.10.053 Liu, 2010, Capsaicinoids in the hottest pepper Bhut Jolokia and its antioxidant and anti inflammatory activities, Nat Prod Commun, 5, 91 Zhang, 2007, Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity, Circ Res, 100, 1063, 10.1161/01.RES.0000262653.84850.8b Kawabata, 2009, Non-pungent capsaicin analogs (capsinoids) increase metabolic rate and enhance thermogenesis via gastrointestinal TRPV1 in mice, Biosci Biotechnol Biochem, 73, 2690, 10.1271/bbb.90555 Luo, 2012, TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice, Cell Res, 22, 551, 10.1038/cr.2011.205 Westerterp-Plantenga, 2005, Sensory and gastrointestinal satiety effects of capsaicin on food intake, Int J Obes (Lond), 299, 682, 10.1038/sj.ijo.0802862 Clegg, 2012, Combined medium-chain triglyceride and chilli feeding increases diet-induced thermogenesis in normal weight humans, Eur J Nutr, 52, 1579, 10.1007/s00394-012-0463-9 Ludy, 2012, The effects of capsaicin and capsiate on energy balance: critical review and meta-analyses of studies in humans, Chem Senses, 37, 103, 10.1093/chemse/bjr100 Janssens, 2013, Acute effects of capsaicin on energy expenditure and fat oxidation in negative energy balance, PLoS One, 8, e67786, 10.1371/journal.pone.0067786 Hursel, 2010, Thermogenic ingredients and body weight regulation, Int J Obes (Lond), 34, 659, 10.1038/ijo.2009.299 Yoneshiro, 2012, Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans, Am J Clin Nutr, 95, 845, 10.3945/ajcn.111.018606 Dietrich, 2013, Hypothalamic control of energy balance: insights into the role of synaptic plasticity, Trends Neurosci, 36, 65, 10.1016/j.tins.2012.12.005 Menigoz, 2011, The expression pattern of TRPV1 in brain, J Neurosci, 31, 13025, 10.1523/JNEUROSCI.2589-11.2011 Bishnoi, 2011, Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats, J Pain, 12, 991, 10.1016/j.jpain.2011.03.005 Musso, 2010, Obesity, diabetes and gut microbiota, Diabetes Care, 33, 2277, 10.2337/dc10-0556 Cryan, 2012, Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour, Nat Rev Neurosci, 13, 701, 10.1038/nrn3346 Everard, 2013, Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity, Proc Natl Acad Sci U S A, 110, 9066, 10.1073/pnas.1219451110 Brown, 2012, Diet induced dysbiosis of the intestinal microbiota and the effects on immunity and disease, Nutrients, 4, 1095, 10.3390/nu4081095 Sharma, 2013, Capsicum annuum enhances l-lactate production by Lactobacillus acidophilus: implication in curd formation, J Dairy Sci, 96, 4142, 10.3168/jds.2012-6243 Singh, 2013, Verapamil augments the neuroprotectant action of berberine in rat model of transient global cerebral ischemia, Eur J Pharmacol, 720, 98, 10.1016/j.ejphar.2013.10.043 Ahern, 2013, Transient receptor potential channels and energy homeostasis, Trends Endocrinol Metab, 24, 554, 10.1016/j.tem.2013.06.005 Ludy, 2011, The effects of hedonically acceptable red pepper doses on thermogenesis and appetite, Physiol Behav, 102, 251, 10.1016/j.physbeh.2010.11.018 Kang, 2011, Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice, J Med Food, 14, 310, 10.1089/jmf.2010.1367 Lee, 2013, Topical application of capsaicin reduces visceral adipose fat by affecting adipokine levels in high-fat diet-induced obese mice, Obesity (Silver Spring), 21, 115, 10.1002/oby.20246 Kang, 2010, Dietary capsaicin reduces obesity-induced insulin resistance and hepatic steatosis in obese mice fed a high-fat diet, Obesity, 18, 780, 10.1038/oby.2009.301 Okumura, 2012, Effect of caffeine and capsaicin on the blood glucose levels of obese/diabetic KK-A(y) mice, J Oleo Sci, 61, 515, 10.5650/jos.61.515 Fekete, 2011, Systemic urocortin 2, but not urocortin 1 or stressin1-A, suppresses feeding cia CRF2 receptors without malaise and stress, Br J Pharmacol, 164, 1959, 10.1111/j.1476-5381.2011.01512.x Fekete, 2007, Review physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs, Front Neuroendocrinol, 28, 1, 10.1016/j.yfrne.2006.09.002 Wang, 2001, Peripheral urocortin inhibits gastric emptying and food intake in mice: differential role of CRF receptor 2, Am J Physiol Regul Integr Comp Physiol, 281, R1401, 10.1152/ajpregu.2001.281.5.R1401 Rios, 2013, BDNF and the central control of feeding: accidental bystander or essential player?, Trends Neurosci, 36, 83, 10.1016/j.tins.2012.12.009 Liao, 2012, Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin, Nat Med, 18, 564, 10.1038/nm.2687 Cao, 2011, White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis, Cell Metab, 14, 324, 10.1016/j.cmet.2011.06.020 Lee, 2004, Expressional changes of neuropeptide Y and cholecystokinin in the arcuate and paraventricular nuclei after capsaicin administration, J Nutr Sci Vitaminol (Tokyo), 50, 144, 10.3177/jnsv.50.144 Ono, 2011, Intragastric administration of capsiate, a transient receptor potential channel agonist, triggers thermogenic sympathetic responses, J Appl Physiol, 110, 789, 10.1152/japplphysiol.00128.2010 Fromme, 2011, Uncoupling protein 1 expression and high-fat diets, Am J Physiol Regul Integr Comp Physiol, 300, R1, 10.1152/ajpregu.00411.2010 Rippe, 2000, Effect of high-fat diet, surrounding temperature, and enterostatin on uncoupling protein gene expression, Am J Physiol Endocrinol Metab, 279, E293, 10.1152/ajpendo.2000.279.2.E293 Yoneshiro, 2013, Transient receptor potential activated brown fat thermogenesis as a target of food ingredients for obesity management, Curr Opin Clin Nutr Metab Care, 16, 625, 10.1097/MCO.0b013e3283653ee1 Yoneshiro, 2013, Recruited brown adipose tissue as an anti-obesity agent in humans, J Clin Investig, 123, 3404, 10.1172/JCI67803 Saito, 2013, Capsinoids and related food ingredients activating brown fat thermogenesis and reducing body fat in humans, Curr Opin Lipidol, 24, 71, 10.1097/MOL.0b013e32835a4f40 Birerdinc, 2013, Manipulating molecular switches in brown adipocytes and their precursors: a therapeutic potential, Prog Lipid Res, 52, 51, 10.1016/j.plipres.2012.08.001 Iwasaki, 2011, TRPV1 agonist monoacylglycerol increases UCP1 content in brown adipose tissue and suppresses accumulation of visceral fat in mice fed a high-fat and high-sucrose diet, Biosci Biotechnol Biochem, 75, 904, 10.1271/bbb.100850 Seale, 2011, Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice, J Clin Invest, 121, 96, 10.1172/JCI44271 Kajimura, 2014, A new era in brown adipose tissue biology: molecular control of brown fat development and energy homeostasis, Annu Rev Physiol, 76, 225, 10.1146/annurev-physiol-021113-170252 Delzenne, 2011, Modulation of the gut microbiota by nutrients with prebiotic properties: consequences for host health in the context of obesity and metabolic syndrome, Microb Cell Fact, 10, S10, 10.1186/1475-2859-10-S1-S10 Ley, 2006, Microbial ecology: human gut microbes associated with obesity, Nature, 444, 1022, 10.1038/4441022a Ley, 2005, Obesity alters gut microbial ecology, Proc Natl Acad Sci U S A, 102, 11070, 10.1073/pnas.0504978102 Ouchi, 2011, Adipokines in inflammation and metabolic disease, Nat Rev Immunol, 11, 85, 10.1038/nri2921 Santacruz, 2010, Gut microbiota composition is associated with body weight, weight gain and biochemical parameters in pregnant women, Br J Nutr, 104, 83, 10.1017/S0007114510000176 Hansen, 2012, Early life treatment with vancomycin propagates Akkermansia muciniphila and reduces diabetes incidence in the NOD mouse, Diabetologia, 55, 2285, 10.1007/s00125-012-2564-7 Derrien, 2004, Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium, Int J Syst Evol Microbiol, 54, 1469, 10.1099/ijs.0.02873-0 Everard, 2011, Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice, Diabetes, 60, 2775, 10.2337/db11-0227 Shin, 2014, An increase in the Akkermansia spp. population induced by metformin treatment improves glucose homeostasis in diet-induced obese mice, Gut, 63, 727, 10.1136/gutjnl-2012-303839 Baboota, 2013, Functional food ingredients for the management of obesity and associated co-morbidities — a review, J Funct Foods, 5, 997, 10.1016/j.jff.2013.04.014 Kim, 2012, High fat diet-induced gut microbiota exacerbates inflammation and obesity in mice via the TLR4 signaling pathway, PLoS One, 7, e47713, 10.1371/journal.pone.0047713