Candida tropicalis induces NLRP3 inflammasome activation via glycogen metabolism-dependent glycolysis and JAK-STAT1 signaling pathway in myeloid-derived suppressor cells to promote colorectal carcinogenesis

International Immunopharmacology - Tập 113 - Trang 109430 - 2022
Zhiyong Zhang1,2, Ying Chen1,2, Yuxin Yin1,2, Yuxi Chen1,2, Qianyu Chen1,2, Ziqian Bing1,2, Yaojun Zheng1,2, Yayi Hou1,2, Sunan Shen1,2, Yitian Chen3, Tingting Wang1,2
1The State Key Laboratory of Pharmaceutical Biotechnology, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China
2Jiangsu Key Laboratory of Molecular Medicine, Division of Immunology, Medical School, Nanjing University, Nanjing 210093, China
3Department of Medical Oncology, School of Medicine, Jingling Hospital, Nanjing University, Nanjing, China

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