Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer

Oncotarget - Tập 7 Số 12 - Trang 13269-13284 - 2016
Raghavendra A. Shamanna1, Huiming Lu1, Deborah L. Croteau1, Arvind Arora2, Devika Agarwal3, Graham Ball3, Mohammed A. Aleskandarany2, Ian O. Ellis2, Yves Pommier4, Srinivasan Madhusudan2, Vilhelm A. Bohr1
1Laboratory of Molecular Gerontology, Biomedical Research Center, National Institute on Aging, NIH, Baltimore, Maryland, USA
2Academic Unit of Oncology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK
3School of Science and Technology, Nottingham Trent University, Clifton Campus, Nottingham NG11 8NS, UK
4Developmental Therapeutics Branch and Laboratory of Molecular Pharmacology, National Cancer Institute, Bethesda, Maryland, USA

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