Callus mineralization and maturation are delayed during fracture healing in interleukin-6 knockout mice

Bone - Tập 41 Số 6 - Trang 928-936 - 2007
Xu Yang1, Benjamin F. Ricciardi1, Alexia Hernandez-Soria1, Yuexian Shi1, Nancy P. Camacho1, Mathias P. Bostrom1
1The Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA

Tóm tắt

Từ khóa


Tài liệu tham khảo

Einhorn, 1995, The expression of cytokine activity by fracture callus, J Bone Miner Res, 10, 1272, 10.1002/jbmr.5650100818

Einhorn, 1998, The cell and molecular biology of fracture healing, Clin Orthop Relat Res, 355S, S7, 10.1097/00003086-199810001-00003

Andrew, 1995, Platelet-derived growth factor expression in normally healing human fractures, Bone, 16, 455

Gerstenfeld, 2001, Impaired intramembranous bone formation during bone repair in the absence of tumor necrosis factor-alpha signaling, Cells Tissues Organs, 169, 285, 10.1159/000047893

Lieberman, 2002, The role of growth factors in the repair of bone, J Bone Jt Surg, 84-A, 1032, 10.2106/00004623-200206000-00022

Wong, 2003, The role of the interleukin-6 family of cytokines in inflammatory arthritis and bone turnover, Arthritis Rheum, 48, 1177, 10.1002/art.10943

Littlewood, 1991, The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro, Endocrinology, 129, 1513, 10.1210/endo-129-3-1513

Haynes, 1997, Regulation of bone cells by particle-activated mononuclear phagocytes, J Bone Jt Surg [Br], 79-B, 988, 10.1302/0301-620X.79B6.7832

Heymann, 2000, Gp130 cytokine family and bone cells, Cytokine, 12, 1455, 10.1006/cyto.2000.0747

Kudo, 2003, Interleukin-6 and interleukin-11 support human osteoclast formation by a RANKL-independent mechanism, Bone, 32, 1, 10.1016/S8756-3282(02)00915-8

Adebanjo, 1998, Mode of action of interleukin-6 on mature osteoclasts. Novel interactions with extracellular Ca2+ sensing in the regulation of osteoclastic bone resorption, J Cell Biol, 142, 1347, 10.1083/jcb.142.5.1347

Palmqvist, 2002, IL-6, leukemia inhibitory factor, and oncostatin M stimulate bone resorption and regulate the expression of receptor activator of NF-kappa B ligand, osteoprotegerin, and receptor activator of NF-kappa B in mouse calvariae, J Immunol, 169, 3353, 10.4049/jimmunol.169.6.3353

Cohen, 1996, Interleukin 6 induces the expression of vascular endothelial growth factor, J Biol Chem, 271, 736, 10.1074/jbc.271.2.736

Gardner, 2006, In vivo cyclic axial compression affects bone healing in the mouse tibia, J Orthop Res, 24, 1679, 10.1002/jor.20230

Camacho, 2003, Fourier transform infrared imaging spectroscopy (FT-IRIS) of mineralization in bisphosphonate-treated oim/oim mice, Calcif Tissue Int, 72, 604, 10.1007/s00223-002-1038-1

Gadaleta, 1996, Fourier transform infrared spectroscopy of the solution-mediated conversion of amorphous calcium phosphate to hydroxyapatite: new correlations between X-ray diffraction and infrared data, Calcif Tissue Int, 58, 9, 10.1007/BF02509540

Goldner, 1938, A modification of the Masson trichrome technique for routine laboratory purposes, Am J Pathol, 14, 237

Motyckova, 2002, Pycnodysostosis: role and regulation of cathepsin K in osteoclast function and human disease, Curr Mol Med, 2, 407, 10.2174/1566524023362401

Takasaki, 1981, A nuclear antigen associated with cell proliferation and blast transformation, J Exp Med, 154, 1899, 10.1084/jem.154.6.1899

Kon, 2001, Expression of osteoprotegerin, receptor of activator of NF-kB ligand and related proinflammatory cytokines during fracture healing, J Bone Miner Res, 16, 1004, 10.1359/jbmr.2001.16.6.1004

Flick, 2003, Effects of receptor activator of NFkB (RANK) signaling blockade on fracture healing, J Orthop Res, 21, 676, 10.1016/S0736-0266(03)00011-1

Lehmann, 2005, Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing, Bone, 36, 300, 10.1016/j.bone.2004.10.010

Kloen, 2003, BMP signaling components are expressed in human fracture callus, Bone, 33, 362, 10.1016/S8756-3282(03)00191-1

Street, 2002, Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover, Proc Natl Acad Sci U S A, 99, 9656, 10.1073/pnas.152324099

Cho, 2002, Differential temporal expression of members of the transforming growth factor beta superfamily during murine fracture healing, J Bone Miner Res, 17, 513, 10.1359/jbmr.2002.17.3.513

Ling, 2005, DMP1 depletion decreases bone mineralization in vivo: an FTIR imaging analysis, J Bone Miner Res, 20, 2169, 10.1359/JBMR.050815

Boskey, 1998, Fourier transform infrared microspectroscopic analysis of bones of osteocalcin-deficient mice provides insight into the function of osteocalcin, Bone, 23, 187, 10.1016/S8756-3282(98)00092-1

Magne, 2003, Phosphate is a specific signal for ATDC5 chondrocyte maturation and apoptosis-associated mineralization: possible implication of apoptosis in the regulation of endochondral ossification, J Bone Miner Res, 18, 1430, 10.1359/jbmr.2003.18.8.1430

Matsushima, 1989, Age changes in the crystallinity of bone mineral and in the disorder of its crystal, Biochim Biophys Acta, 992, 155, 10.1016/0304-4165(89)90004-4

Poli, 1994, Interleukin-6 deficient mice are protected from bone loss caused by estrogen depletion, EMBO J, 13, 1189, 10.1002/j.1460-2075.1994.tb06368.x

Jikko, 1998, Effects of interleukin-6 on proliferation and proteoglycan metabolism in articular chondrocyte cultures, Cell Biol Int, 22, 615, 10.1006/cbir.1998.0304

Kitamura, 1995, Bone marrow neutrophilia and suppressed bone turnover in human interleukin-6 transgenic mice, Am J Pathol, 147, 1682

Solis-Herruzo, 1999, Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts, J Biol Chem, 274, 30919, 10.1074/jbc.274.43.30919

Franchimont, 1997, Interleukin-6 and its soluble receptor cause a marked induction of collagenase 3 expression in rat osteoblast cultures, J Biol Chem, 272, 12144, 10.1074/jbc.272.18.12144

Flannery, 2000, IL-6 and its soluble receptor augment aggrecanase-mediated proteoglycan catabolism in articular cartilage, Matrix Biol, 19, 549, 10.1016/S0945-053X(00)00111-6

Lin, 2003, Essential involvement of IL-6 in the skin wound-healing process as evidenced by delayed wound healing in IL-6-deficient mice, J Leukoc Biol, 73, 713, 10.1189/jlb.0802397

Neale, 1999, Macrophage colony-stimulating factor and interleukin-6 release by periprosthetic cells stimulates osteoclast formation and bone resorption, J Orthop Res, 17, 686, 10.1002/jor.1100170510

Tamura, 1993, Soluble interleukin-6 receptor triggers osteoclast formation by interleukin 6, Proc Natl Acad Aci U S A, 90, 11924, 10.1073/pnas.90.24.11924

Gorny, 2004, IL-6, LIF, and TNF-alpha regulation of GM-CSF inhibition of osteoclastogenesis in vitro, Exp Cell Res, 294, 149, 10.1016/j.yexcr.2003.11.009

Strecker, 1999, Early biochemical characterization of soft-tissue trauma and fracture trauma, J Trauma, 47, 358, 10.1097/00005373-199908000-00025

Gerstenfeld, 2003, Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption, J Bone Miner Res, 8, 1584, 10.1359/jbmr.2003.18.9.1584

Atti, 2002, Effects of transforming growth factor-beta deficiency on bone development: a Fourier transform-infrared imaging analysis, Bone, 31, 675, 10.1016/S8756-3282(02)00905-5

Boskey, 2003, Infrared analysis of the mineral and matrix in bones of osteonectin-null mice and their wildtype controls, J Bone Miner Res, 18, 1005, 10.1359/jbmr.2003.18.6.1005

Maes, 2006, Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair, J Clin Invest, 116, 1230, 10.1172/JCI26772

Kayal, 2007, Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity, J Bone Miner Res, 22, 560, 10.1359/jbmr.070115