Calcitonin: Effect on protein synthesis in different rat tissues
Tóm tắt
Protein synthesis was inhibited in the pancreas whereas it was enhanced in the kidney and intestine (jejunumileum) after a single injection of porcine calcitonin (20 MRC units/kg b.wt). The incorporation of [3H]leucine into total protein in the brain, heart, liver and stomach did not change after the hormone treatment.
Tài liệu tham khảo
A. M. Nakhla and A. P. N. Majumdar, Biochem. J.170, 445 (1978).
H. D. Becker, S. J. Konturek, D. D. Reeder and J. C. Thompson, Am. J. Physiol.225, 277 (1973).
J. Hotz, H. Goebell and R. Ziegler, Gut18, 615 (1977).
T. K. Gray, P. Brannan, D. Juan, S. G. Morawski and J. S. Fordtran, Gastroenterology71, 392 (1976).
M. W. Walling, T. A. Brasitus and D. V. Kimberg, Gastroenterology73 89 (1977).
G. L. Melson, L. R. Chase and G. D. Aurbach, Endocrinology86, 511 (1970).
A. M. Nakhla and A. Latif, Biochem. J.176, 339 (1978).
R. W. Wannemacher, Jr, W. L. Banks, Jr., and W. H. Wunner, Analyt. Biochem.11, 320 (1965).
A. P. N. Majumdar and A. M. Nakhla, Br. J. Pharmac., in press (1979).
O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. biol. Chem.193, 265 (1951).