Cadonilimab plus anlotinib effectively relieve rare cardiac angiosarcoma with multiple metastases: a case report and literature review

Clinical Research in Cardiology - Tập 113 - Trang 358-365 - 2023
Ziyue Zeng1, Zijie Mei2, Min Chen2, Hong Cao3, Qingming Xiang2, Huanhuan Cai1, Zhibing Lu1, Hui Qiu2
1Department of Cardiology, Zhongnan Hospital of Wuhan University, Wuhan, China
2Department of Gynecological Tumor Radiotherapy and Chemotherapy, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Zhongnan Hospital of Wuhan University, Wuhan, China
3Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China

Tài liệu tham khảo

Holzhauser L, Heymer J, Kasner M, Landmesser U, Skurk C (2015) Rare case of a multilocular primary cardiac intimal sarcoma presenting as left atrial mass with new onset atrial fibrillation. Eur Heart J 36(35):2402. https://doi.org/10.1093/eurheartj/ehv215 Campanile A, Tavazzi G, Alam MH et al (2016) An unexpected finding in an asymptomatic patient with atrial fibrillation: CA. Lancet 387(10036):e29. https://doi.org/10.1016/S0140-6736(16)00086-6 Igarashi Y, Sasada T (2020) Cancer vaccines: toward the next breakthrough in cancer immunotherapy. J Immunol Res 2020:5825401. https://doi.org/10.1155/2020/5825401 Urbini M, Astolfi A, Indio V et al (2020) Genetic aberrations and molecular biology of cardiac sarcoma. Ther Adv Med Oncol 12:1758835920918492. https://doi.org/10.1177/1758835920918492 Brennan MF, Antonescu CR, Moraco N, Singer S (2014) Lessons learned from the study of 10,000 patients with soft tissue sarcoma. Ann Surg 260(3):416–421. https://doi.org/10.1097/SLA.0000000000000869. (discussion 421–2) Siegel RL, Miller KD, Jemal A (2020) Cancer statistics, 2020. CA Cancer J Clin 70(1):7–30. https://doi.org/10.3322/caac.21590 Dajsakdipon T, Siripoon T, Ngamphaiboon N, Ativitavas T, Dejthevaporn T (2022) Immunotherapy and biomarkers in sarcoma. Curr Treat Options Oncol 23(3):415–438. https://doi.org/10.1007/s11864-022-00944-6 Antonescu C (2014) Malignant vascular tumors—an update. Mod Pathol 27(Suppl 1):S30–S38. https://doi.org/10.1038/modpathol Khan JA, Maki RG, Ravi V (2018) Pathologic angiogenesis of malignant vascular sarcomas: implications for treatment. J Clin Oncol 36(2):194–201. https://doi.org/10.1200/JCO.2017.74.9812 Nizam A, Paquette EL, Wang BG, Aragon-Ching JB (2018) Epithelioid angiosarcoma of the bladder: a case report and review of the literature. Clin Genitourin Cancer 16(6):e1091–e1095. https://doi.org/10.1016/j.clgc.2018.07.010 Florou V, Wilky BA (2021) Current management of angiosarcoma: recent advances and lessons from the past. Curr Treat Options Oncol 22(7):61. https://doi.org/10.1007/s11864-021-00858-9 Cao J, Wang J, He C, Fang M (2019) Angiosarcoma: a review of diagnosis and current treatment. Am J Cancer Res 9(11):2303–2313 O’Donovan C, Davern M, Donlon NE, Lysaght J, Conroy MJ (2021) Chemokine-targeted therapies: an opportunity to remodel immune profiles in gastro-oesophageal tumours. Cancer Lett 521:224–236. https://doi.org/10.1016/j.canlet.2021.09.005 Yao W, Du X, Wang J, Wang X, Zhang P, Niu X (2022) Long-term efficacy and safety of anlotinib as a monotherapy and combined therapy for advanced sarcoma. Onco Targets Ther 15:669–679. https://doi.org/10.2147/OTT.S365506 Ropp AM, Burke AP, Kligerman SJ, Leb JS, Frazier AA (2021) Intimal sarcoma of the great vessels. Radiographics 41(2):361–379. https://doi.org/10.1148/rg.2021200184 Zhu MMT, Shenasa E, Nielsen TO (2020) Sarcomas: immune biomarker expression and checkpoint inhibitor trials. Cancer Treat Rev 91:102115. https://doi.org/10.1016/j.ctrv.2020.102115 Hod N, Shalev A, Levin D, Anconina R, Ezroh Kazap D, Lantsberg S (2018) FDG PET/CT of CA with pulmonary metastases. Clin Nucl Med 43(10):744–746. https://doi.org/10.1097/RLU.0000000000002215 Naruse G, Kawasaki M, Yanase K, Tanaka T (2020) Primary angiosarcoma in the right atrium diagnosed by a cardiac tumor biopsy using intracardiac echocardiography. J Med Ultrasound 28(2):120–122. https://doi.org/10.4103/JMU.JMU_93_19 Hendriksen BS, Stahl KA, Hollenbeak CS et al (2019) Postoperative chemotherapy and radiation improve survival following cardiac sarcoma resection. J Thorac Cardiovasc Surg. https://doi.org/10.1016/j.jtcvs.2019.10.016 Li X, Lan L, Hu H (2022) Case report: primary CA with multiple metastases. Front Cardiovasc Med 28(9):941967. https://doi.org/10.3389/fcvm.2022.941967 Donmez AA, Cekmecelioglu D, Adademir T, Yilmaz E, Alp HM (2018) Primary CA with rare presenting feature and successful surgical treatment. Braz J Cardiovasc Surg 33(5):525–527. https://doi.org/10.21470/1678-9741-2017-0239 Berry MF, Williams M, Welsby I, Lin S (2010) CA presenting with right coronary artery pseudoaneurysm. J Cardiothorac Vasc Anesth 24(4):633–635. https://doi.org/10.1053/j.jvca.2009.04.002 Wang C, Shi M, Yang C, Ma T, Jiang J, Liu Y, Xi W, Zhu Z, Zhang J (2017) Comprehensive treatment of unresectable CA: a case report and review of literature. Mol Clin Oncol 7(5):859–863. https://doi.org/10.3892/mco.2017.1390 Mangla A, Gupta A, Mansur DB, Abboud S, Rothermel LD, Oliveira GH (2021) Right atrial CA treated with concurrent proton beam therapy and paclitaxel: a novel approach to a rare disease. Thorac Cancer 12(7):1131–1133. https://doi.org/10.1111/1759-7714.13895 Honda Y, Otsuka A, Ono S et al (2016) Infiltration of PD-1-positive cells in combination with tumor site PD-L1 expression is a positive prognostic factor in cutaneous angiosarcoma. Oncoimmunology 6(1):e1253657. https://doi.org/10.1080/2162402X.2016.1253657 Hofer S, Zeidler K, Schipf A, Kempf W, Zimmermann D, Aebi S (2018) Angiosarcoma of the scalp responding to nivolumab: a case report. Br J Dermatol 179(2):530–531. https://doi.org/10.1111/bjd.16698 Constantinidou A, Sauve N, Stacchiotti S et al (2020) Evaluation of the use and efficacy of (neo)adjuvant chemotherapy in angiosarcoma: a multicentre study. ESMO Open 5(4):e000787. https://doi.org/10.1136/esmoopen-2020-000787 D’Angelo SP, Mahoney MR, Van Tine BA et al (2018) Nivolumab with or without ipilimumab treatment for metastatic sarcoma (Alliance A091401): two open-label, non-comparative, randomised, phase 2 trials. Lancet Oncol 19(3):416–426. https://doi.org/10.1016/S1470-2045(18)30006-8 Sindhu S, Gimber LH, Cranmer L, McBride A, Kraft AS (2017) Angiosarcoma treated successfully with anti-PD-1 therapy—a case report. J Immunother Cancer 5(1):58. https://doi.org/10.1186/s40425-017-0263-0 Vasella M, Gousopoulos E, Guidi M et al (2022) Targeted therapies and checkpoint inhibitors in sarcoma. QJM 115(12):793–805. https://doi.org/10.1093/qjmed/hcab014 Kelly CM, Antonescu CR, Bowler T et al (2020) Objective response rate among patients with locally advanced or metastatic sarcoma treated with talimogene laherparepvec in combination with pembrolizumab: a phase 2 clinical trial. JAMA Oncol 6(3):402–408. https://doi.org/10.1001/jamaoncol.2019.6152 D’Angelo SP, Richards AL, Conley AP et al (2022) Pilot study of bempegaldesleukin in combination with nivolumab in patients with metastatic sarcoma. Nat Commun 13(1):3477. https://doi.org/10.1038/s41467-022-30874-8 Liu Z, Gao S, Zhu L et al (2021) Efficacy and safety of anlotinib in patients with unresectable or metastatic bone sarcoma: a retrospective multiple institution study. Cancer Med 10(21):7593–7600. https://doi.org/10.1002/cam4.4286 Mai H, Lin S, Chen D et al (2021) 436 A phase II study of AK104, a bispecific antibody targeting PD-1 and CTLA-4, in patients with metastatic nasopharyngeal carcinoma (NPC) who had progressed after two or more lines of chemotherapy. J ImmunoTherapy Cancer. https://doi.org/10.1136/jitc-2021-SITC2021.436 Li J, Cao P, Chen Y et al (2022) Anlotinib combined with the PD-L1 blockade exerts the potent anti-tumor immunity in renal cancer treatment. Exp Cell Res 417(1):113197. https://doi.org/10.1016/j.yexcr.2022.113197 Painter CA, Jain E, Tomson BN et al (2020) The Angiosarcoma Project: enabling genomic and clinical discoveries in a rare cancer through patient-partnered research. Nat Med 26(2):181–187. https://doi.org/10.1038/s41591-019-0749-z Mehnert JM, Panda A, Zhong H et al (2016) Immune activation and response to pembrolizumab in POLE-mutant endometrial cancer. J Clin Invest 126(6):2334–2340. https://doi.org/10.1172/JCI84940